FIH-1: a novel protein that interacts with HIF-1α and VHL to mediate repression of HIF-1 transcriptional activity

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2. Transcriptional Regulation of Serine/Threonine Kinase-15 (STK15) Expression by Hypoxia and HIF-1
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3. Genetic causes of erythrocytosis and the oxygen-sensing pathway
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4. Mutual Regulation between Redox and Hypoxia-Inducible Factors in Cardiovascular and Renal Complications of Diabetes
   Carla Iacobini, Martina Vitale, Jonida Haxhi, Carlo M. Pesce, Giuseppe Pugliese, Stefano Menini · 2022 · Antioxidants
5. The role of miRNAs in stress-responsive hepatic stellate cells during liver fibrosis
   Joeri Lambrecht, Inge Mannaerts, Leo A. van Grunsven · 2015 · Frontiers in Physiology
6. Involvement of Hypoxia-Inducible Factors in the Dysregulation of Oxygen Homeostasis in Sepsis
   Kiichi Hirota · 2015 · Cardiovascular & Haematological Disorders - Drug Targets
7. Regulation of hypoxia-inducible factor functions in the nucleus by sphingosine-1-phosphate
   Hait, Nitai C., Maiti, Aparna, Xu, Pan, Qi, Qianya, Kawaguchi, Tsutomu, Okano, Maiko, Takabe, Kazuaki, Yan, Li, Luo, Cheng · 2020 · The FASEB Journal
8. Gene expression profiling of human primary astrocytes exposed to manganese chloride indicates selective effects on several functions of the cells
   Amitabha Sengupta, Sarah M. Mense, Changgui Lan, Mei Zhou, Rory E. Mauro, Lisa Kellerman, Galina Bentsman, David J. Volsky, Elan D. Louis, Joseph H. Graziano et al. · 2006 · NeuroToxicology
9. Normoxic Activation of Hypoxia-Inducible Factors in Photoreceptors Provides Transient Protection against Light-Induced Retinal Degeneration
   Christina Lange, Severin Reinhard Heynen, Naoyuki Tanimoto, Markus Thiersch, Yun-Zheng Le, Isabelle Meneau, Mathias W. Seeliger, Marijana Samardzija, Christian Caprara, Christian Grimm · 2011 · Investigative Ophthalmology & Visual Science
10. Molecular characterization and mRNA expression of hypoxia inducible factor-1 and cognate inhibiting factor in Macrobrachium nipponense in response to hypoxia
    Shengming Sun, Fujun Xuan, Hongtuo Fu, Xianping Ge, Jian Xin Zhu, Hui Qiao, Shubo Jin, Wenyi Zhang · 2016 · Comparative Biochemistry and Physiology Part B Biochemistry and Molecular Biology
11. Promoting vascularization for tissue engineering constructs: current strategies focusing on HIF-regulating scaffolds
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12. Metabolic, Anti-apoptotic and Immune Evasion Strategies of Primary Human Myeloma Cells Indicate Adaptations to Hypoxia*
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13. Hypoxia-Inducible Factor (HIF): Fuel for Cancer Progression
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14. RNA Interference in Aquaculture: A Small Tool for Big Potential
    Haitham G. Abo‐Al‐Ela · 2021 · Journal of Agricultural and Food Chemistry
15. Targeting glycolysis by 3-bromopyruvate improves tamoxifen cytotoxicity of breast cancer cell lines
    Yasmin M. Attia, Hanan Salah El-Abhar, Mahmoud M. Al Marzabani, Samia A. Shouman · 2015 · BMC Cancer
16. Regulation of myogenesis by environmental hypoxia
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17. Nitric oxide signalling and cellular adaptations to changes in oxygenation
    Lynne-Marie M Postovit, Richard Sullivan, Michael A. Adams, Charles H. Graham · 2004 · Toxicology
18. The Normobaric Oxygen Paradox—Hyperoxic Hypoxic Paradox: A Novel Expedient Strategy in Hematopoiesis Clinical Issues
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19. Factor inhibiting HIF1α (FIH-1) functions as a tumor suppressor in human colorectal cancer by repressing HIF1α pathway
    Tao Chen, Zhong Ren, Lechi Ye, Ping‐Hong Zhou, Jianmin Xu, Qiang Shi, Li-Qing Yao, Yunshi Zhong · 2015 · Cancer Biology & Therapy
20. The asparaginyl hydroxylase factor-inhibiting HIF is essential for tumor growth through suppression of the p53–p21 axis
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21. PRDX2 and PRDX4 are negative regulators of hypoxia-inducible factors under conditions of prolonged hypoxia
    Weibo Luo, Ivan Chen, Yan Chen, Duah Alkam, Yingfei Wang, Gregg L. Semenza · 2016 · Oncotarget
22. Coordinate regulation of stress signaling and epigenetic events by Acss2 and HIF-2 in cancer cells
    Rui Chen, Min Xu, Jason S. Nagati, Joseph A. Garcia · 2017 · PLoS ONE
23. Nuclear FGFR2 negatively regulates hypoxia-induced cell invasion in prostate cancer by interacting with HIF-1 and HIF-2
    Jae Eun Lee, Seung-Hyun Shin, Hyun‐Woo Shin, Yang‐Sook Chun, Jong‐Wan Park · 2019 · Scientific Reports
24. Activin-A limits Th17 pathogenicity and autoimmune neuroinflammation via CD39 and CD73 ectonucleotidases and Hif1-α–dependent pathways
    Ioannis Morianos, Aikaterini I. Trochoutsou, Gina Papadopoulou, Maria Semitekolou, Aggelos Banos, Dimitris Konstantopoulos, Antigoni Manousopoulou, Μαρία Καπασά, Ping Yen Wei, Brett Lomenick et al. · 2020 · Proceedings of the National Academy of Sciences
25. Cannabidiol Suppresses Angiogenesis and Stemness of Breast Cancer Cells by Downregulation of Hypoxia-Inducible Factors-1α
    Min Jee Jo, Bu Gyeom Kim, Woo Young Kim, Dae-Hee Lee, Hye Kyeong Yun, Soyeon Jeong, Seong Hye Park, Bo Ram Kim, Jung Lim Kim, Dae Yeong Kim et al. · 2021 · Cancers
26. Elucidating the role of hypoxia-inducible factor in rheumatoid arthritis
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27. Hypoxia-inducible factors: roles in cardiovascular disease progression, prevention, and treatment
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28. Cooperativity of Stress-Responsive Transcription Factors in Core Hypoxia-Inducible Factor Binding Regions
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29. Lipopolysaccharide and Hypoxia‐Induced HIF‐1 Activation in Human Gingival Fibroblasts
    Jingping Li, Francois Y.L. Li, Aimin Xu, Bin Cheng, Sai Wah Tsao, Man‐Lung Fung, Wai Keung Leung · 2011 · Journal of Periodontology
30. Physiology meets biophysics: Visualizing the interaction of hypoxia-inducible factor 1α with p300 and CBP
    Gregg L. Semenza · 2002 · Proceedings of the National Academy of Sciences
31. Hypoxia-inducible factor-1α polymorphisms and TSC1/2 mutations are complementary in head and neck cancers
    CARLA A. HEBERT, Kathleen Norris, Pallavi Parashar, Robert Andrew Ord, Nikolaos G. Nikitakis, John J. Sauk · 2006 · Molecular Cancer
32. Regulation of P-Glycoprotein during Oxidative Stress
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33. Epigenetic regulation of hypoxia inducible factor in diseases and therapeutics
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34. Factor inhibiting HIF limits the expression of hypoxia-inducible genes in podocytes and distal tubular cells
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35. Tumor Hypoxia: Causative Mechanisms, Microregional Heterogeneities, and the Role of Tissue-Based Hypoxia Markers
    Peter W. Vaupel, Arnulf Mayer · 2016 · Advances in experimental medicine and biology
36. Investigational hypoxia-inducible factor prolyl hydroxylase inhibitors (HIF-PHI) for the treatment of anemia associated with chronic kidney disease
    Lucia Del Vecchio, Francesco Locatelli · 2018 · Expert Opinion on Investigational Drugs
37. Spectroscopic and Electronic Structure Study of ETHE1: Elucidating the Factors Influencing Sulfur Oxidation and Oxygenation in Mononuclear Nonheme Iron Enzymes
    Serra Goudarzi, Jeffrey Thomas Babicz, Ömer Kabil, Ruma V. Banerjee, Edward I. Solomon · 2018 · Journal of the American Chemical Society
38. Interaction of the Ankyrin H Core Effector of Legionella with the Host LARP7 Component of the 7SK snRNP Complex
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39. Oxygen-dependent hydroxylation by Factor Inhibiting HIF (FIH) regulates the TRPV3 ion channel
    Sarah Karttunen, Michael D. Duffield, Nathan Robert Scrimgeour, Lauren Squires, Wai Li Lim, Mark L. Dallas, Jason L. Scragg, Johana Chicher, Keyur A. Dave, Murray L. Whitelaw et al. · 2014 · Journal of Cell Science
40. Inhibition of Hypoxia-inducible Factor-targeting Prolyl Hydroxylase Domain-containing Protein 2 (PHD2) Enhances Matrix Synthesis by Human Chondrocytes
    Brendan L. Thoms, Christopher L. Murphy · 2010 · Journal of Biological Chemistry
41. Auto-hydroxylation of FIH-1: an Fe(ii), α-ketoglutarate-dependent human hypoxia sensor
    Yuan-Han Chen, Lindsay M. Comeaux, Stephen J. Eyles, Michael J. Knapp · 2008 · Chemical Communications
42. Emerging evidence of the physiological role of hypoxia in mammary development and lactation
    Yong Shao, Feng‐Qi Zhao · 2014 · Journal of Animal Science and Biotechnology/Journal of animal science and biotechnology
43. Oxygen-Dependent Modulation of Insulin-Like Growth Factor Binding Protein Biosynthesis in Primary Cultures of Rat Hepatocytes
    Jens‐Gerd Scharf, Terry G. Unterman, Thomas Kietzmann · 2005 · Endocrinology
44. Conditional hypoxia inducible factor-1α induction in embryonic pulmonary epithelium impairs maturation and augments lymphangiogenesis
    James P. Bridges, Sui Lin, Machiko Ikegami, John M. Shannon · 2011 · Developmental Biology
45. Association between the polymorphisms in exon 12 of hypoxia-inducible factor-1α and the clinicopathological features of oral squamous cell carcinoma
    Tzong‐Ming Shieh, Kuo‐Wei Chang, Hsi‐Feng Tu, Yin-Hua Shih, Shun-Yao Ko, Yuan-Chien Chen, Chung‐Ji Liu · 2010 · Oral Oncology
46. The chromatin remodeler ISWI regulates the cellular response to hypoxia: role of FIH
    Andrew Melvin, Sharon Mudie, Sónia Rocha · 2011 · Molecular Biology of the Cell
47. The Impact of Hypoxia and Mesenchymal Transition on Glioblastoma Pathogenesis and Cancer Stem Cells Regulation
    Michael J. Karsy, Jian Guan, Randy L. Jensen, Eric L. Huang, Howard Colman · 2015 · World Neurosurgery
48. Hypoxia-induced Downregulation of SRC-3 Suppresses Trophoblastic Invasion and Migration Through Inhibition of the AKT/mTOR Pathway: Implications for the Pathogenesis of Preeclampsia
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49. ERK signaling controls productive HIF‐1 binding to chromatin and cancer cell adaptation to hypoxia through HIF‐1α interaction with NPM1
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50. 2-Oxoglutarate derivatives can selectively enhance or inhibit the activity of human oxygenases
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51. Abundance of aspargynyl-hydroxylase FIH is regulated by Siah-1 under normoxic conditions
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52. Leu-574 of HIF-1α Is Essential for the von Hippel-Lindau (VHL)-mediated Degradation Pathway
    Eric L. Huang, Erin A. Pete, Maureen Schau, Justine Milligan, Jie Gu · 2002 · Journal of Biological Chemistry
53. Inhibitor of nuclear factor‐kappaB alpha derepresses hypoxia‐inducible factor‐1 during moderate hypoxia by sequestering factor inhibiting hypoxia‐inducible factor from hypoxia‐inducible factor 1α
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54. Written asthma action plans
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55. Role of the HIF oxygen sensing pathway in cell defense and proliferation through the control of amino acid metabolism
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56. Endothelial oxygen sensors regulate tumor vessel abnormalization by instructing phalanx endothelial cells
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57. Regulated Function of the Prolyl-4-Hydroxylase Domain (PHD) Oxygen Sensor Proteins
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58. When hypoxia signalling meets the ubiquitin-proteasomal pathway, new targets for cancer therapy
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59. Current Understanding of HIF in Renal Disease
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60. Mitochondria: Oxygen sinks rather than sensors?
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61. The hypoxic response and aging
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62. The role of HIF in angiogenesis, lymphangiogenesis, and tumor microenvironment in urological cancers
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63. Hypoxia Inducible Factor 3α Plays a Critical Role in Alveolarization and Distal Epithelial Cell Differentiation during Mouse Lung Development
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64. Current views on cell metabolism in SDHx-related pheochromocytoma and paraganglioma
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65. Hypoxia-Inducible Factors: Post-translational Crosstalk of Signaling Pathways
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66. MicroRNAs regulate survival in oxygen-deprived environments
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67. Breakthrough science: hypoxia-inducible factors, oxygen sensing, and disorders of hematopoiesis
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68. Role of abnormal energy metabolism in the progression of chronic kidney disease and drug intervention
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69. Hypoxia as a target for drug combination therapy of liver cancer
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70. Overexpression of factor inhibiting HIF‐1 enhances vessel maturation and tumor growth via platelet‐derived growth factor‐C
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71. HIF-1α protects osteoblasts from ROS-induced apoptosis
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72. OTUB1 augments hypoxia signaling via its non-canonical ubiquitination inhibition of HIF-1α during hypoxia adaptation
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73. Hypoxia-Inducible Factor-Dependent and Independent Mechanisms Underlying Chemoresistance of Hypoxic Cancer Cells
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74. Romance of the three kingdoms in hypoxia: HIFs, epigenetic regulators, and chromatin reprogramming
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75. Vegfa promoter gene hypermethylation at HIF1α binding site is an early contributor to CKD progression after renal ischemia
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76. Down-Regulation of the Expression of the FIH-1 and ARD-1 Genes at the Transcriptional Level by Nickel and Cobalt in the Human Lung Adenocarcinoma A549 Cell Line
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77. Integration of hypoxic HIF-α signaling in blood cancers
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78. POU6F1 cooperates with RORA to suppress the proliferation of lung adenocarcinoma by downregulating HIF1A signaling pathway
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79. Precision Mechanics with Multifunctional Tools: How HnRNP K and HnRNPs E1/E2 Contribute to Post-Transcriptional Control of Gene Expression in Hematopoiesis
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80. New Classes of Mind Bomb-Interacting Proteins Identified from Yeast Two-Hybrid Screens
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81. Role Of Hif2α Oxygen Sensing Pathway In Bronchial Epithelial Club Cell Proliferation
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83. ARDent about acetylation and deacetylation in hypoxia signalling
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84. Modulation of vascular gene expression by hypoxia
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87. Periostin inhibits hypoxia-induced apoptosis in human periodontal ligament cells via TGF-β signaling
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91. Biochemistry of the hypoxia-inducible factor hydroxylases
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92. Retinal neuroprotection by hypoxic preconditioning is independent of hypoxia‐inducible factor‐1α expression in photoreceptors
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96. Molecular Biology of Renal Cortical Tumors
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97. Retinoblastoma susceptibility gene product pRB activates hypoxia-inducible factor-1 (HIF-1)
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