FIH-1: a novel protein that interacts with HIF-1α and VHL to mediate repression of HIF-1 transcriptional activity

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Items 301–400 of 1,002

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    Albanese, Adam, Daly, Leonard A., Mennerich, Daniela, Kietzmann, Thomas, Sée, Violaine · 2020 · International Journal of Molecular Sciences
  3. Recent developments in the regulation of the angiogenic switch by cellular stress factors in tumors
    Sophie North, Michel Moenner, Andréas Bikfalvi · 2004 · Cancer Letters
  4. HIF-1 mediates pathogenic inflammatory responses to intestinal ischemia-reperfusion injury
    Rena Feinman, Edwin A. Deitch, Anthony C. Watkins, Billy Abungu, Iriana Colorado, Kolenkode B. Kannan, Sharvil U. Sheth, Francis J. Caputo, Qi Lu, Madhuri Ramanathan et al. · 2010 · American Journal of Physiology-Gastrointestinal and Liver Physiology
  5. Transcriptional Response to Hypoxia: The Role of HIF-1-Associated Co-Regulators
    Angelos Yfantis, Ilias Mylonis, Georgia Chachami, Marios Nikolaidis, Grigoris D. Amoutzias, Efrosyni Paraskeva, George Simos · 2023 · Cells
  6. Regulation of Hypoxia‐Inducible Factors During Inflammation
    Stilla Frede, Utta Berchner‐Pfannschmidt, Joachim Fandrey · 2007 · Methods in enzymology on CD-ROM/Methods in enzymology
  7. Ancient Atmospheres and the Evolution of Oxygen Sensing Via the Hypoxia-Inducible Factor in Metazoans
    Taylor, Cormac T., McElwain, Jennifer C. · 2010 · Physiology
  8. Hypoxia-Inducible Factor-1: A Critical Player in the Survival Strategy of Stressed Cells
    Shuyang Chen, Nianli Sang · 2015 · Journal of Cellular Biochemistry
  9. The Genomics and Genetics of Oxygen Homeostasis
    Gregg L. Semenza · 2020 · Annual Review of Genomics and Human Genetics
  10. HIF-1
    Patrick Henry Maxwell · 2003 · Journal of the American Society of Nephrology
  11. Circulating tumour cells demonstrate an altered response to hypoxia and an aggressive phenotype
    Kurosh Ameri, Richard H. Luong, Haiyu Zhang, Ashley A. Powell, Kelli D. Montgomery, Íñigo Espinosa, Donna M. Bouley, Adrian Llewellyn Harris, Stefanie S. Jeffrey · 2010 · British Journal of Cancer
  12. Lack of oxygen in articular cartilage: consequences for chondrocyte biology
    Jérôme E. Lafont · 2010 · International Journal of Experimental Pathology
  13. Role of reactive oxygen species in the regulation of HIF-1 by prolyl hydroxylase 2 under mild hypoxia
    Niecknig, Helene, Tug, Suzan, Reyes, Buena Delos, Kirsch, Michael, Fandrey, Joachim, Berchner-Pfannschmidt, Utta · 2012 · Free Radical Research
  14. Mitochondrial regulation of oxygen sensing
    Bell, Eric L., Emerling, Brooke M., Chandel, Navdeep S. · 2005 · Mitochondrion
  15. HIF2α signaling inhibits adherens junctional disruption in acute lung injury
    Haixia Gong, Jalees Rehman, Haiyang Tang, Kishore K. Wary, Manish Mittal, Pallavi Chatturvedi, You‐Yang Zhao, Yulia A. Komorova, Stephen M. Vogel, Asrar B. Malik · 2015 · Journal of Clinical Investigation
  16. Strange Bedfellows: Nuclear Factor, Erythroid 2-Like 2 (Nrf2) and Hypoxia-Inducible Factor 1 (HIF-1) in Tumor Hypoxia
    Rachel K. Toth, Noel A. Warfel · 2017 · Antioxidants
  17. Transcriptional responses to intermittent hypoxia
    Jayasri Nanduri, Guoxiang Yuan, Ganesh K Kumar, Gregg L. Semenza, Nanduri R. Prabhakar · 2008 · Respiratory Physiology & Neurobiology
  18. Inhibition of mitochondrial respiration elevates oxygen concentration but leaves regulation of hypoxia-inducible factor (HIF) intact
    Doege, Kathrin, Heine, Sandra, Jensen, Inga, Jelkmann, Wolfgang, Metzen, Eric · 2005 · Blood
  19. Renal erythropoietin-producing cells in health and disease
    Tomokazu Souma, Norio Suzuki, Masayuki P. Yamamoto · 2015 · Frontiers in Physiology
  20. HIF-1 in Cell Cycle Regulation, Apoptosis, and Tumor Progression
    Nobuhito Goda, Sara J. Dozier, Randall S. Johnson · 2003 · Antioxidants and Redox Signaling
  21. Dynamic HIF1A Regulation During Human Placental Development1
    Ietta, Francesca, Wu, Yuanhong, Winter, Jennifer, Xu, Jing, Wang, Jinxia, Post, Martin, Caniggia, Isabella · 2006 · Biology of Reproduction
  22. Methylation of hypoxia-inducible factor (HIF)-1α by G9a/GLP inhibits HIF-1 transcriptional activity and cell migration
    Lei Bao, Yan Chen, Hsien‐Tsung Lai, Shwu-Yuan Wu, Jennifer E. Wang, Kimmo J. Hatanpaa, Jack M. Raisanen, Miles R. Fontenot, Bradley Charles Lega, Cheng‐Ming Chiang et al. · 2018 · Nucleic Acids Research
  23. Identification of genes induced by BRCA1 in breast cancer cells
    Arzu Atalay, Tim J. Crook, Mehmet Öztürk, Işık G. Yuluğ · 2002 · Biochemical and Biophysical Research Communications
  24. Hypoxia‐inducible factor 1: a new hope to counteract neurodegeneration?
    Sónia C. Correia, Paula Isabel Moreira · 2009 · Journal of Neurochemistry
  25. Development of mi RNA ‐based therapeutic approaches for cancer patients
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  26. A Critical Evaluation of DNA Adducts as Biological Markers for Human Exposure to Polycyclic Aromatic Compounds
    Roger Godschalk, Frederik‐Jan van Schooten, Helmut Bartsch · 2003 · BMB Reports
  27. Human Placental Hypoxia-Inducible Factor-1α Expression Correlates with Clinical Outcomes in Chronic Hypoxia in Vivo
    Zamudio, Stacy, Wu, Yuanhong, Ietta, Francesca, Rolfo, Alessandro, Cross, Ashley, Wheeler, Timothy, Post, Martin, Illsley, Nicholas P., Caniggia, Isabella · 2007 · The American Journal of Pathology
  28. Hypoxia inducible factor in hepatocellular carcinoma: A therapeutic target
    Daniel Lin · 2015 · World Journal of Gastroenterology
  29. Activation of hypoxia-inducible factor 1 during macrophage differentiation
    Tomoyuki Oda, Kiichi Hirota, Kenichiro Nishi, Satoshi Takabuchi, Seiko Oda, Hiroko Yamada, Toshiyuki Arai, Kazuhiko Fukuda, Toru Kita, Takehiko Adachi et al. · 2006 · American Journal of Physiology-Cell Physiology
  30. Erythropoietin regulation of red blood cell production: from bench to bedside and back
    Senthil Velan Bhoopalan, Lily Jun-shen Huang, Mitchell J. Weiss · 2020 · F1000Research
  31. The role of hypoxia-inducible factor-2 in digestive system cancers
    Zhao, J, Du, F, Shen, G, Zheng, F, Xu, B · 2015 · Cell Death & Disease
  32. AMPK-HDAC5 pathway facilitates nuclear accumulation of HIF-1α and functional activation of HIF-1 by deacetylating Hsp70 in the cytosol
    Shuyang Chen, Chengqian Yin, Taotao Lao, Dongming Liang, Dan He, Chenguang Wang, Nianli Sang · 2015 · Cell Cycle
  33. HIF at the crossroads between ischemia and carcinogenesis
    Stefan Paul, Jonathan W. Simons, Nicola J. Mabjeesh · 2004 · Journal of Cellular Physiology
  34. Role of hypoxia-inducible factor-1α as a cancer therapy target
    Shalini Patiar, Adrian Llewellyn Harris · 2006 · Endocrine Related Cancer
  35. Structure of Human FIH-1 Reveals a Unique Active Site Pocket and Interaction Sites for HIF-1 and von Hippel-Lindau
    Cheolju Lee, Seung Jun Kim, Dae Gwin Jeong, Soon Mi Lee, Seong Eon Ryu · 2003 · Journal of Biological Chemistry
  36. Transcriptional control of adenosine signaling by hypoxia-inducible transcription factors during ischemic or inflammatory disease
    Jens Martin Poth, Kelley S. Brodsky, Heidi Ehrentraut, Almut Grenz, Holger K. Eltzschig · 2012 · Journal of Molecular Medicine
  37. MicroRNA as Therapeutic Targets for Chronic Wound Healing
    Eoghan J. Mulholland, Nicholas Dunne, Helen O. McCarthy · 2017 · Molecular Therapy — Nucleic Acids
  38. Modulation of gene expression by hypoxia in human umbilical cord vein endothelial cells: A transcriptomic and proteomic study
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  39. Development of novel therapeutic strategies that target HIF-1
    Gregg L. Semenza · 2006 · Expert Opinion on Therapeutic Targets
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  41. The TNF-α/ROS/HIF-1-induced Upregulation of FoxMI Expression Promotes HCC Proliferation and Resistance to Apoptosis
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  42. Hypoxia inducible factor-1: a novel target for cancer therapy
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  43. Hypoxia inducible factor-2α: a critical mediator of aggressive tumor phenotypes
    Guoliang Qing, Marie Celeste Simon · 2009 · Current Opinion in Genetics & Development
  44. Regulation of Hypoxia-Inducible Factor (HIF)-1 Activity and Expression of HIF Hydroxylases in Response to Insulin-Like Growth Factor I
    Caroline Treins, Sophie Giorgetti‐Peraldi, Joseph Murdaca, Marie-Noëlle Monthouel, Emmanuel VAN OBBERGHEN · 2005 · Molecular Endocrinology
  45. The gut in iron homeostasis: role of HIF-2 under normal and pathological conditions
    Mastrogiannaki, Maria, Matak, Pavle, Peyssonnaux, Carole · 2013 · Blood
  46. Regulated oxygen sensing by protein hydroxylation in renal erythropoietin-producing cells
    Roland H. Wenger, David Hoogewijs · 2010 · American Journal of Physiology-Renal Physiology
  47. Hypoxia-induced angiogenesis in human hepatocellular carcinoma
    Kwang-Rok Kim, Hyo-Eun Moon, Kyu‐Won Kim · 2002 · Journal of Molecular Medicine
  48. microRNA-31/factor-inhibiting hypoxia-inducible factor 1 nexus regulates keratinocyte differentiation
    Han Peng, Nihal Kaplan, Robert B. Hamanaka, Julia Katsnelson, Hanz B. Blatt, Wending Yang, Liangliang Hao, Paul J. Bryar, Randall S. Johnson, Spiro Getsios et al. · 2012 · Proceedings of the National Academy of Sciences
  49. Hypoxia, HIF, and Associated Signaling Networks in Chronic Kidney Disease
    Jing Liu, Qingqing Wei, Chunyuan Guo, Guie Dong, Yu Liu, Chengyuan Tang, Zheng Dong · 2017 · International Journal of Molecular Sciences
  50. Micromanaging aerobic respiration and glycolysis in cancer cells
    Ayla Orang, Janni Petersen, Ross Allan McKinnon, Michael Michael · 2019 · Molecular Metabolism
  51. Hypoxia inducible factor-1α: Its role in colorectal carcinogenesis and metastasis
    Ganji Purnachandra Nagaraju, Pallaval Veera Bramhachari, Godi Raghu, Bassel F. El‐Rayes · 2015 · Cancer Letters
  52. Hypoxia-inducible factor 1–mediated characteristic features of cancer cells for tumor radioresistance
    Hiroshi Harada · 2016 · Journal of Radiation Research
  53. A compendium of proteins that interact with HIF-1α
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  54. Hypoxia-inducible factor 1 signalling, metabolism and its therapeutic potential in cardiovascular disease
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  55. Tumor Dormancy and Interplay with Hypoxic Tumor Microenvironment
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  56. Repair of Critical-Sized Rat Calvarial Defects Using Genetically Engineered Bone Marrow-Derived Mesenchymal Stem Cells Overexpressing Hypoxia-Inducible Factor-1α
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  57. A dynamic model of the hypoxia-inducible factor 1-alpha (HIF-1α) network
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  58. HIF-α Prolyl Hydroxylase Inhibitors and Their Implications for Biomedicine: A Comprehensive Review
    Kiichi Hirota · 2021 · Biomedicines
  59. HIFs, Hypoxia, and Vascular Development
    Kelly L. Covello, Marie Celeste Simon · 2004 · Current topics in developmental biology/Current Topics in Developmental Biology
  60. Abnormalities in Oxygen Sensing Define Early and Late Onset Preeclampsia as Distinct Pathologies
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  62. Physiologic responses to hypoxia and implications for hypoxia‐inducible factors in the pathogenesis of rheumatoid arthritis
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    Jorge Lira Ruas, Lorenz Poellinger, Teresa Pereira · 2002 · Journal of Biological Chemistry
  64. Hypoxia-inducible factor prolyl hydroxylase 2 has a high affinity for ferrous iron and 2-oxoglutarate
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  65. miR-135a contributes to paclitaxel resistance in tumor cells both in vitro and in vivo
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  68. Suppression of microRNA-31 increases sensitivity to 5-FU at an early stage, and affects cell migration and invasion in HCT-116 colon cancer cells
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  69. Malignant Glioma Physiology: Cellular Response to Hypoxia and Its Role in Tumor Progression
    Daniel Jay Brat, Timothy B. Mapstone · 2003 · Annals of Internal Medicine
  70. PCAF is an HIF-1α cofactor that regulates p53 transcriptional activity in hypoxia
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  71. Exosomes secreted from mutant‐HIF‐1α‐modified bone‐marrow‐derived mesenchymal stem cells attenuate early steroid‐induced avascular necrosis of femoral head in rabbit
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  72. Hypoxia: molecular pathophysiological mechanisms in human diseases
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  73. Proteasomal Inhibition Attenuates Transcriptional Activity of Hypoxia-Inducible Factor 1 (HIF-1) via Specific Effect on the HIF-1α C-Terminal Activation Domain
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  74. Interaction of the TAZ1 Domain of the CREB-Binding Protein with the Activation Domain of CITED2
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  75. Histone Deacetylase Inhibitors Repress the Transactivation Potential of Hypoxia-inducible Factors Independently of Direct Acetylation of HIF-α
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  80. Impaired Oxygen-dependent Reduction of HIF-1α and -2α Proteins in Pre-eclamptic Placentae
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  81. An intimate crosstalk between iron homeostasis and oxygen metabolism regulated by the hypoxia-inducible factors (HIFs)
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  82. VHL Gene Mutations and Their Effects on Hypoxia Inducible Factor HIFα: Identification of Potential Driver and Passenger Mutations
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  83. Hypoxia Inducible Factor (HIF) Hydroxylases as Regulators of Intestinal Epithelial Barrier Function
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  84. Suppression of Hypoxia-inducible Factor 1α (HIF-1α) Transcriptional Activity by the HIF Prolyl Hydroxylase EGLN1
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