The DOI matches its Crossref record; 34 of the 34 references it cites were found in a registry or an index.
Fast and flexible simulation of DNA sequence data
Open accessAbstract
Simulation of genomic sequences under the coalescent with recombination has conventionally been impractical for regions beyond tens of megabases. This work presents an algorithm, implemented as the program MaCS (Ma rkovian C oalescent S imulator), that can efficiently simulate haplotypes under any arbitrary model of population history. We present several metrics comparing the performance of MaCS with other available simulation programs. Practical usage of MaCS is demonstrated through a comparison of measures of linkage disequilibrium between generated program output and real genotype data from populations considered to be structured.
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Cites
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A second generation human haplotype map of over 3.1 million SNPs
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On the number of segregating sites in genetical models without recombination
Watterson, G. A. (1975) · Theoretical Population Biology · doi:10.1016/0040-5809(75)90020-9 · Cited by 3,915
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A Map of Recent Positive Selection in the Human Genome
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Generating samples under a Wright–Fisher neutral model of genetic variation
Hudson, R. R. (2002) · Bioinformatics · doi:10.1093/bioinformatics/18.2.337 · Cited by 2,364
Variant of transcription factor 7-like 2 (TCF7L2) gene confers risk of type 2 diabetes
Grant, S. F. A., Thorleifsson, G., Reynisdottir, I., Benediktsson, R., Manolescu, A., Sainz, J., Helgason, A., Stefansson, H., Emilsson, V., Helgadottir, A., et al. (2006) · Nature Genetics · doi:10.1038/ng1732 · Cited by 2,287
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Cited by
Ancient Admixture in Human History
Patterson, N., Moorjani, P., Luo, Y., Mallick, S., Rohland, N., Zhan, Y., Genschoreck, T., Webster, T., & Reich, D. (2012) · Genetics · doi:10.1534/genetics.112.145037 · Cited by 2,848
Approximate Bayesian Computation (ABC) in practice
Csilléry, K., Blum, M. G. B., Gaggiotti, O. E., & François, O. (2010) · Trends in Ecology & Evolution · doi:10.1016/j.tree.2010.04.001 · Cited by 1,302
Inferring human population size and separation history from multiple genome sequences
Schiffels, S., & Durbin, R. (2014) · Nature Genetics · doi:10.1038/ng.3015 · Cited by 1,073
A genetic atlas of human admixture history
Hellenthal, G., Busby, G. B. J., Band, G., Wilson, J. F., Capelli, C., Falush, D., & Myers, S. (2014) · Science · doi:10.1126/science.1243518 · Cited by 798
Reconstructing routes of invasion using genetic data: why, how and so what?
ESTOUP, A., & GUILLEMAUD, T. (2010) · Molecular Ecology · doi:10.1111/j.1365-294x.2010.04773.x · Cited by 649
Metadata
- Authors
- Chen, G. K., Marjoram, P., & Wall, J. D.
- Venue
- Genome Research
- Publisher
- Cold Spring Harbor Laboratory
- Published
- 2008-11-24
- Volume
- 19
- Issue
- 1
- Pages
- 136-142
- ISSN
- 1088-9051 (ISSN-L)
- OpenAlex
- W2165141658
- Cited by
- 406
- References
- 34
- Type
- posted content
- Language
- en
- Open access
- bronze
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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