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Generating samples under a Wright–Fisher neutral model of genetic variation
Open accessAbstract
Summary: A Monte Carlo computer program is available to generate samples drawn from a population evolving according to a Wright–Fisher neutral model. The program assumes an infinite-sites model of mutation, and allows recombination, gene conversion, symmetric migration among subpopulations, and a variety of demographic histories. The samples produced can be used to investigate the sampling properties of any sample statistic under these neutral models. Availability: The source code for the program (in the language C) is available at http://home.uchicago.edu/~rhudson1/source/mksamples.html. Contact: rr-hudson@uchicago.edu
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Cited by
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“In our applications, we estimate variances using simulations from the coalescent simulator ms [35].”
MethodInfluential
Metadata
- Authors
- Hudson, R. R.
- Venue
- Bioinformatics
- Publisher
- Oxford University Press (OUP)
- Published
- 2002-02-01
- Volume
- 18
- Issue
- 2
- Pages
- 337-338
- ISSN
- 1367-4803 (ISSN-L)
- 1367-4811
- OpenAlex
- W2134599124
- Cited by
- 2,364
- References
- 0
- FWCI
- 25.68
- Type
- journal article
- Language
- en
- Open access
- bronze
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