The DOI matches its Crossref record; 4 of the 4 references it cites were found in a registry or an index.
Spidey: A Tool for mRNA-to-Genomic Alignments
Open accessAbstract
We have developed a computer program that aligns spliced sequences to genomic sequences, using local alignment algorithms and heuristics to put together a global spliced alignment. Spidey can produce reliable alignments quickly, even when confronted with noise from alternative splicing, polymorphisms, sequencing errors, or evolutionary divergence. We show how Spidey was used to align reference sequences to known genomic sequences and then to the draft human genome, to align mRNAs to gene clusters, and to align mouse mRNAs to human genomic sequence. We compared Spidey to two other spliced alignment programs; Spidey generally performed quite well in a very reasonable amount of time.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Initial sequencing and analysis of the human genome
International Human Genome Sequencing Consortium, Whitehead Institute for Biomedical Research, C. F. G. R., Lander, E. S., Linton, L. M., Birren, B., Nusbaum, C., Zody, M. C., Baldwin, J., Devon, K., Dewar, K., et al. (2001) · Nature · doi:10.1038/35057062 · Cited by 24,216
Self-citationA Computer Program for Aligning a cDNA Sequence with a Genomic DNA Sequence
Florea, L., Hartzell, G., Zhang, Z., Rubin, G. M., & Miller, W. (1998) · Genome Research · doi:10.1101/gr.8.9.967 · Cited by 729
EST_GENOME: a program to align spliced DNA sequences to unspliced genomic DNA
Mott, R. (1997) · Bioinformatics · doi:10.1093/bioinformatics/13.4.477 · Cited by 276
Introducing RefSeq and LocusLink: curated human genome resources at the NCBI
Pruitt, K. D., Katz, K. S., Sicotte, H., & Maglott, D. R. (2000) · Trends in Genetics · doi:10.1016/s0168-9525(99)01882-x · Cited by 241
Cited by
GMAP: A genomic mapping and alignment program for mRNA and EST sequences
Wu, T. D., & Watanabe, C. K. (2005) · Bioinformatics · doi:10.1093/bioinformatics/bti310 · Cited by 2,354
Improving the Arabidopsis genome annotation using maximal transcript alignment assemblies
Haas, B. J. (2003) · Nucleic Acids Research · doi:10.1093/nar/gkg770 · Cited by 2,296
PerlPrimer: cross-platform, graphical primer design for standard, bisulphite and real-time PCR
Marshall, O. J. (2004) · Bioinformatics · doi:10.1093/bioinformatics/bth254 · Cited by 677
A beginner’s guide to eukaryotic genome annotation
Yandell, M., & Ence, D. (2012) · Nature Reviews Genetics · doi:10.1038/nrg3174 · Cited by 588
The DNA sequence of human chromosome 7
Hillier, L. W., Fulton, R. S., Fulton, L. A., Graves, T. A., Pepin, K. H., Wagner-McPherson, C., Layman, D., Maas, J., Jaeger, S., Walker, R., et al. (2003) · Nature · doi:10.1038/nature01782 · Cited by 285
Metadata
- Authors
- Wheelan, S. J., Church, D. M., & Ostell, J. M.
- Venue
- Genome Research
- Publisher
- Cold Spring Harbor Laboratory
- Published
- 2001-10-15
- Volume
- 11
- Issue
- 11
- Pages
- 1952-1957
- ISSN
- 1088-9051 (ISSN-L)
- 1549-5469
- OpenAlex
- W1749816123
- Cited by
- 302
- References
- 4
- Type
- posted content
- Language
- en
- Open access
- bronze
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Spidey: A Tool for mRNA-to-Genomic Alignments. https://app.cochat.ai/papers/10.1101/gr.195301
- The paper
- Wheelan, S. J., Church, D. M., & Ostell, J. M. (2001). Spidey: A Tool for mRNA-to-Genomic Alignments. Genome Research. https://doi.org/10.1101/gr.195301
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.