The DOI matches its Crossref record; 9 of the 9 references it cites were found in a registry or an index.
Emerging technologies in DNA sequencing
Open accessAbstract
Demand for DNA sequence information has never been greater, yet current Sanger technology is too costly, time consuming, and labor intensive to meet this ongoing demand. Applications span numerous research interests, including sequence variation studies, comparative genomics and evolution, forensics, and diagnostic and applied therapeutics. Several emerging technologies show promise of delivering next-generation solutions for fast and affordable genome sequencing. In this review article, the DNA polymerase-dependent strategies of Sanger sequencing, single nucleotide addition, and cyclic reversible termination are discussed to highlight recent advances and potential challenges these technologies face in their development for ultrafast DNA sequencing.
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Cites
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Cited by
Velvet: Algorithms for de novo short read assembly using de Bruijn graphs
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Sequencing technologies – the next generation
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Self-citationReal-Time DNA Sequencing from Single Polymerase Molecules
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Prescribing Personalized Nutrition for Cardiovascular Health: Are We Ready?
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The Diploid Genome Sequence of an Individual Human
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Metadata
- Authors
- Metzker, M. L.
- Venue
- Genome Research
- Publisher
- Cold Spring Harbor Laboratory
- Published
- 2005-12
- Volume
- 15
- Issue
- 12
- Pages
- 1767-1776
- ISSN
- 1088-9051 (ISSN-L)
- OpenAlex
- W2140897574
- Cited by
- 491
- References
- 9
- Type
- posted content
- Language
- en
- Open access
- bronze
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