The New Genomics: Global Views of Biology

Quantitative Monitoring of Gene Expression Patterns with a Complementary DNA Microarray

Schena, M., Shalon, D., Davis, R. W., & Brown, P. O. (1995) · Science · doi:10.1126/science.270.5235.467 · Cited by 9,609 · see citing works

Genetic Dissection of Complex Traits

Lander, E. S., & Schork, N. J. (1994) · Science · doi:10.1126/science.8091226 · Cited by 3,425 · see citing works

Mapping the Protein Universe

Holm, L., & Sander, C. (1996) · Science · doi:10.1126/science.273.5275.595 · Cited by 1,504 · see citing works

Accessing Genetic Information with High-Density DNA Arrays

Chee, M. S., Robert Che-An, Y. A. N. G., Hubbell, E. A., Berno, A. J., Huang, X. C., Stern, D. T., Winkler, J., Lockhart, D. J., Morris, M. S., & Fodor, S. P. A. (1996) · Science · doi:10.1126/science.274.5287.610 · Cited by 1,493 · see citing works

Gene duplications and the origins of vertebrate development

Holland, P. W. H., García‐Fernàndez, J., Williams, N. A., & Sidow, A. (1994) · Development · doi:10.1242/dev.1994.supplement.125 · Cited by 951 · see citing works

An STS-Based Map of the Human Genome

Hudson, T. J., Stein, L. D., Gerety, S. S., Ma, J., Castle, A. B., Silva, J., Slonim, D. K., Baptista, R., Kruglyak, L., Xu, S., et al. (1995) · Science · doi:10.1126/science.270.5244.1945 · Cited by 773 · see citing works

Circuit Simulation of Genetic Networks

McAdams, H. H., & Shapiro, L. (1995) · Science · doi:10.1126/science.7624793 · Cited by 519 · see citing works

A protein linkage map of Escherichia coli bacteriophage T7

Bartel, P. L., Roecklein, J. A., SenGupta, D., & Fields, S. (1996) · Nature Genetics · doi:10.1038/ng0196-72 · Cited by 333 · see citing works

Initial sequencing and analysis of the human genome

International Human Genome Sequencing Consortium, Whitehead Institute for Biomedical Research, C. F. G. R., Lander, E. S., Linton, L. M., Birren, B., Nusbaum, C., Zody, M. C., Baldwin, J., Devon, K., Dewar, K., et al. (2001) · Nature · doi:10.1038/35057062 · Cited by 24,216 · see citing works

Molecular classification of cancer: class discovery and class prediction by gene expression monitoring

Golub, T. R., Slonim, D. K., Tamayo, P., Huard, C., Gaasenbeek, M., Mesirov, J. P., Coller, H., Loh, M. L., Downing, J. R., Caligiuri, M. A., et al. (1999) · Science · doi:10.1126/science.286.5439.531 · Cited by 11,516 · see citing works

The Structure of Haplotype Blocks in the Human Genome

Gabriel, S. B., Schaffner, S. F., Nguyen, H., Moore, J. M., Roy, J., Blumenstiel, B., Higgins, J., DeFelice, M., Lochner, A., Faggart, M., et al. (2002) · Science · doi:10.1126/science.1069424 · Cited by 5,863 · see citing works

A map of human genome sequence variation containing 1.42 million single nucleotide polymorphisms

The International SNP Map Working Group, Laboratories:, C. S. H., Sachidanandam, R., Weissman, D., Schmidt, S. C., Kakol, J. M., Stein, L. D., National Center for Biotechnology Information:, Marth, G., Sherry, S., et al. (2001) · Nature · doi:10.1038/35057149 · Cited by 2,977 · see citing works

The human cell atlas

Regev, A., Teichmann, S. A., Lander, E. S., Amit, I., Benoist, C., Birney, E., Bodenmiller, B., Campbell, P., Carninci, P., Clatworthy, M., et al. (2017) · eLife · doi:10.7554/elife.27041 · Cited by 2,232 · see citing works

Five Years of GWAS Discovery

Visscher, P. M., Brown, M. A., McCarthy, M. I., & Yang, J. (2012) · The American Journal of Human Genetics · doi:10.1016/j.ajhg.2011.11.029 · Cited by 2,425 · see citing works

A N <scp>EW</scp> A <scp>PPROACH TO</scp> D <scp>ECODING</scp> L <scp>IFE</scp> : Systems Biology

Ideker, T., Galitski, T., & Hood, L. (2001) · Annual Review of Genomics and Human Genetics · doi:10.1146/annurev.genom.2.1.343 · Cited by 1,664 · see citing works

Characterization of single-nucleotide polymorphisms in coding regions of human genes

Cargill, M., Altshuler, D., Ireland, J., Sklar, P., Ardlie, K., Patil, N., Lane, C. R., Lim, E. P., Kalyanaraman, N., Nemesh, J., et al. (1999) · Nature Genetics · doi:10.1038/10290 · Cited by 1,547 · see citing works

Discovering genotypes underlying human phenotypes: past successes for mendelian disease, future approaches for complex disease

Botstein, D., & Risch, N. (2003) · Nature Genetics · doi:10.1038/ng1090 · Cited by 1,503 · see citing works

Genetic Mapping in Human Disease

Altshuler, D., Daly, M. J., & Lander, E. S. (2008) · Science · doi:10.1126/science.1156409 · Cited by 1,452 · see citing works

Prospects for whole-genome linkage disequilibrium mapping of common disease genes

Kruglyak, L. (1999) · Nature Genetics · doi:10.1038/9642 · Cited by 1,416 · see citing works

Gene expression analysis by massively parallel signature sequencing (MPSS) on microbead arrays.

Brenner, S., Johnson, M., Bridgham, J., Golda, G., Lloyd, D. H., Johnson, D., Luo, S., McCurdy, S., Foy, M., Ewan, M., et al. (2000) · Nature Biotechnology · doi:10.1038/76469 · Cited by 1,360 · see citing works

Rare and common variants: twenty arguments

Gibson, G. (2012) · Nature Reviews Genetics · doi:10.1038/nrg3118 · Cited by 1,278 · see citing works

On the allelic spectrum of human disease

Reich, D. E., & Lander, E. S. (2001) · Trends in Genetics · doi:10.1016/s0168-9525(01)02410-6 · Cited by 1,185 · see citing works

Blocks of Limited Haplotype Diversity Revealed by High-Resolution Scanning of Human Chromosome 21

Patil, N., Berno, A. J., Hinds, D. A., Barrett, W. A., Doshi, J. M., Hacker, C. R., Kautzer, C. R., Lee, D. H., Marjoribanks, C., McDonough, D. P., et al. (2001) · Science · doi:10.1126/science.1065573 · Cited by 1,145 · see citing works

Human genetic variation and its contribution to complex traits

Frazer, K. A., Murray, S. S., Schork, N. J., & Topol, E. J. (2009) · Nature Reviews Genetics · doi:10.1038/nrg2554 · Cited by 1,073 · see citing works

Initial impact of the sequencing of the human genome

Lander, E. S. (2011) · Nature · doi:10.1038/nature09792 · Cited by 1,044 · see citing works

A HapMap harvest of insights into the genetics of common disease

Manolio, T. A., Brooks, L. D., & Collins, F. S. (2008) · Journal of Clinical Investigation · doi:10.1172/jci34772 · Cited by 889 · see citing works

Association mapping: critical considerations shift from genotyping to experimental design

Myles, S., Peiffer, J., Brown, P. J., Ersoz, E. S., Zhang, Z., Costich, D. E., & Buckler, E. S. (2009) · The Plant Cell · doi:10.1105/tpc.109.068437 · Cited by 857 · see citing works

The allelic architecture of human disease genes: common disease-common variant... or not?

Pritchard, J. K. (2002) · Human Molecular Genetics · doi:10.1093/hmg/11.20.2417 · Cited by 711 · see citing works

The genetics of asthma and allergic disease: a 21st century perspective

Ober, C., & Yao, T. (2011) · Immunological Reviews · doi:10.1111/j.1600-065x.2011.01029.x · Cited by 698 · see citing works

The genetic epidemiology of neurodegenerative disease

Bertram, L. (2005) · Journal of Clinical Investigation · doi:10.1172/jci24761 · Cited by 680 · see citing works

Genomewide Association Studies: History, Rationale, and Prospects for Psychiatric Disorders

Psychiatric GWAS Consortium Coordinating Committee (2009) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2008.08091354 · Cited by 450 · see citing works

Definition And Clinical Importance Of Haplotypes.

Crawford, D. C., & Nickerson, D. A. (2005) · Annual Review of Medicine · doi:10.1146/annurev.med.56.082103.104540 · Cited by 344 · see citing works

Association of a glutamate (NMDA) subunit receptor gene (GRIN2B) with obsessive-compulsive disorder: a preliminary study

Arnold, P., Rosenberg, D., Mundo, E., Tharmalingam, S., Kennedy, J., & Richter, M. (2004) · Psychopharmacology · doi:10.1007/s00213-004-1847-1 · Cited by 202 · see citing works

Screening a large reference sample to identify very low frequency sequence variants: comparisons between two genes

Glatt, C. E., DeYoung, J. A., Delgado, S., Service, S. K., Giacomini, K. M., Edwards, R. H., Risch, N., & Freimer, N. B. (2001) · Nature Genetics · doi:10.1038/86948 · Cited by 154 · see citing works

Evidence-based psychiatric genetics, AKA the false dichotomy between common and rare variant hypotheses

Visscher, P. M., Goddard, M. E., Derks, E. M., & Wray, N. R. (2012) · Molecular Psychiatry · doi:10.1038/mp.2011.65 · Cited by 138 · see citing works

Schizophrenia susceptibility alleles are enriched for alleles that affect gene expression in adult human brain

Richards, A. L., Jones, L., Moskvina, V, Kirov, G., Gejman, P. V., Levinson, D. F., Sanders, A. R., Molecular Genetics of Schizophrenia Collaboration (MGS), International Schizophrenia Consortium (ISC), Purcell, S., et al. (2012) · Molecular Psychiatry · doi:10.1038/mp.2011.11 · Cited by 123 · see citing works

Apolipoprotein B levels, APOB alleles, and risk of ischemic cardiovascular disease in the general population, a review

Benn, M. (2009) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2009.01.004 · Cited by 119 · see citing works

Meta-analysis of genetic association studies: methodologies, between-study heterogeneity and winner's curse

Nakaoka, H., & Inoue, I. (2009) · Journal of Human Genetics · doi:10.1038/jhg.2009.95 · Cited by 111 · see citing works

Genetic variation in the ABCA1 gene, HDL cholesterol, and risk of ischemic heart disease in the general population

Frikke-Schmidt, R. (2010) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2009.06.005 · Cited by 94 · see citing works

Genome‐wide association studies of multiple sclerosis

Cotsapas, C., & Mitrovic, M. (2018) · Clinical &amp; Translational Immunology · doi:10.1002/cti2.1018 · Cited by 89 · see citing works

Genome-wide association studies and the genetic dissection of complex traits

Sebastiani, P., Timofeev, N., Dworkis, D. A., Perls, T. T., & Steinberg, M. H. (2009) · American Journal of Hematology · doi:10.1002/ajh.21440 · Cited by 67 · see citing works

Implications of multilocus inheritance for gene-disease association studies

Risch, N. (2001) · Theoretical Population Biology · doi:10.1006/tpbi.2001.1538 · Cited by 52 · see citing works

Overview of Marker-assisted Selection in Animal Breeding

Sharma, P., Doultani, S., Hadiya, K. K., George, L., & Highland, H. (2024) · Journal of Advances in Biology &amp; Biotechnology · doi:10.9734/jabb/2024/v27i5790 · Cited by 39 · see citing works

Inflammation as a risk factor for myocardial infarction

Tanaka, T., & Ozaki, K. (2006) · Journal of Human Genetics · doi:10.1007/s10038-006-0411-8 · Cited by 33 · see citing works

Genetic Analysis of Multiple Sclerosis in Europeans

Barcellos, L. F., & Thomson, G. (2003) · Journal of Neuroimmunology · doi:10.1016/j.jneuroim.2003.08.004 · Cited by 25 · see citing works

AlphaFold Database Structure Extractor: a web server and API to download AlphaFold structures using common protein accessions

Saraf, N., Karthik, V., & Sharma, G. (2025) · BMC Bioinformatics · doi:10.1186/s12859-025-06303-0 · Cited by 4 · see citing works

Genomic relationships of N-genome Triticum species

Yen, Y., & KIMBER, G. (1992) · Genome · doi:10.1139/g92-147 · Cited by 17 · see citing works

Identification of signals required for the insertion of heterologous genome segments into the reovirus genome.

Roner, M. R., Lin, P. N., Nepluev, I. V., et al. (1995) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.92.26.12362 · Cited by 21 · see citing works

Estimating the size of the bacterial pan-genome

Lapierre, P., & Gogarten, J. P. (2009) · Trends in Genetics · doi:10.1016/j.tig.2008.12.004 · Cited by 354 · see citing works

Differentiation and inter-genomic relationships among C, E and D genomes in the Oryzaofficinalis complex (Poaceae) as revealed by multicolor genomic in situ hybridization

Li, C., Zhang, D.-M., Ge, S., et al. (2001) · Theoretical and Applied Genetics · doi:10.1007/s001220100562 · Cited by 39 · see citing works

Identification of a unique library of complex, but ordered, arrays of repetitive elements in the human genome and implication of their potential involvement in pathobiology

Lee, K.-H., Lee, Y.-K., Kwon, D.-N., Chiu, S., Chew, V. W., Rah, H., Kujawski, G., Melhem, R., Hsu, K. J., Chung, C. J., et al. (2011) · Experimental and Molecular Pathology · doi:10.1016/j.yexmp.2011.02.007 · Cited by 5 · see citing works