Definition And Clinical Importance Of Haplotypes.

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Variation is the spice of life

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Haplotype Variation and Linkage Disequilibrium in 313 Human Genes

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dbSNP—Database for Single Nucleotide Polymorphisms and Other Classes of Minor Genetic VariationPreprint

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Intensely punctate meiotic recombination in the class II region of the major histocompatibility complex

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Haplotype blocks and linkage disequilibrium in the human genome

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An intronic SNP in a RUNX1 binding site of SLC22A4, encoding an organic cation transporter, is associated with rheumatoid arthritis

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The T309G MDM2 Gene Polymorphism Is a Novel Risk Factor for Proliferative Vitreoretinopathy

Pastor‐Idoate, S., Rodríguez‐Hernández, I., Rojas, J., Fernández, I., García-Gutiérrez, M. T., Ruiz‐Moreno, J. M., Rocha‐Sousa, A., Ramkissoon, Y., Harsum, S., MacLaren, R. E., et al. (2013) · PLoS ONE · doi:10.1371/journal.pone.0082283 · Cited by 41 · see citing works

IL23R haplotypes provide a large population attributable risk for Crohnʼs disease

Taylor, K. D., Targan, S. R., Mei, L., Ippoliti, A., McGovern, D. P. B., Mengesha, E., King, L. M., & Rotter, J. I. (2008) · Inflammatory Bowel Diseases · doi:10.1002/ibd.20478 · Cited by 40 · see citing works

Association of the T‐786C, G894T and 4a/4b polymorphisms of the endothelial nitric oxide synthase gene with vasculogenic erectile dysfunction in Iranian subjects

Safarinejad, M. R., Khoshdel, A., Shekarchi, B., Taghva, A., & Safarinejad, S. (2010) · British Journal of Urology · doi:10.1111/j.1464-410x.2010.09755.x · Cited by 39 · see citing works

Endothelial nitric oxide synthase genotype and haplotype are not associated with diabetic retinopathy in diabetes type 2 patients

de Syllos, R. W. C., Sandrim, V. C., Lisboa, H. R. K., Tres, G. S., & Tanus-Santos, J. E. (2006) · Nitric Oxide · doi:10.1016/j.niox.2006.02.002 · Cited by 39 · see citing works

Matrix metalloproteinase (MMP)-2 gene polymorphisms affect circulating MMP-2 levels in patients with migraine with aura

Gonçalves, F. M., Martins-Oliveira, A., Lacchini, R., Belo, V. D. A., Speciali, J. G., Dach, F., & Tanus-Santos, J. E. (2012) · Gene · doi:10.1016/j.gene.2012.09.109 · Cited by 38 · see citing works

Interaction between FKBP5 gene and childhood trauma on psychosis, depression and anxiety symptoms in a non-clinical sample

de Castro-Català, M., Peña, E., Kwapil, T. R., Papiol, S., Sheinbaum, T., Cristóbal-Narváez, P., Ballespí, S., Barrantes‐Vidal, N., & Rosa, A. (2017) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2017.08.024 · Cited by 38 · see citing works

Acute lung injury and the coagulation pathway: potential role of gene polymorphisms in the protein C and fibrinolytic pathways

Sapru, A., Wiemels, J. L., Witte, J. S., Ware, L. B., & Matthay, M. A. (2006) · Intensive Care Medicine · doi:10.1007/s00134-006-0223-5 · Cited by 38 · see citing works

Endothelial Nitric Oxide Synthase Haplotypes Associated with Aura in Patients with Migraine

Gonçalves, F. M., Martins-Oliveira, A., Speciali, J. G., Luizon, M. R., Izidoro‐Toledo, T. C., Silva, P. S., Dach, F., & Tanus-Santos, J. E. (2011) · DNA and Cell Biology · doi:10.1089/dna.2010.1152 · Cited by 37 · see citing works

Interaction among nitric oxide (NO)-related genes in migraine susceptibility

Gonçalves, F. M., Luizon, M. R., Speciali, J. G., Martins-Oliveira, A., Dach, F., & Tanus-Santos, J. E. (2012) · Molecular and Cellular Biochemistry · doi:10.1007/s11010-012-1409-5 · Cited by 37 · see citing works

Pattern-Recognition Techniques with Haplotype Analysis in Pharmacogenomics

Lin, E., Hwang, Y., Liang, K., & Chen, E. Y. (2006) · Pharmacogenomics · doi:10.2217/14622416.8.1.75 · Cited by 37 · see citing works

Association of RGS2 variants with panic disorder in a Japanese population

Otowa, T., Shimada, T., Kawamura, Y., Sugaya, N., Yoshida, E., Inoue, K., Yasuda, S., Liu, X., Minato, T., Tochigi, M., et al. (2011) · American Journal of Medical Genetics Part B Neuropsychiatric Genetics · doi:10.1002/ajmg.b.31178 · Cited by 36 · see citing works

Vascular Endothelial Growth Factor Genetic Polymorphisms and Haplotypes in Women with Migraine

Gonçalves, F. M., Martins-Oliveira, A., Speciali, J. G., Izidoro‐Toledo, T. C., Luizon, M. R., Dach, F., & Tanus-Santos, J. E. (2010) · DNA and Cell Biology · doi:10.1089/dna.2010.1025 · Cited by 34 · see citing works

The role of stress‐regulation genes in moderating the association of stress and daily‐life psychotic experiences

Cristóbal-Narváez, P., Sheinbaum, T., Myin‐Germeys, I., Kwapil, T. R., de Castro-Català, M., Domínguez‐Martínez, T., Racioppi, A., Monsonet, M., Hinojosa‐Marqués, L., van Winkel, R., et al. (2017) · Acta Psychiatrica Scandinavica · doi:10.1111/acps.12789 · Cited by 34 · see citing works

eNOS haplotype associated with hypertension in obese children and adolescents

Souza-Costa, D. C., Belo, V. D. A., Silva, P. S., Metzger, I. F., Lanna, C. M. M., Machado, M. A., & Tanus-Santos, J. E. (2010) · International Journal of Obesity · doi:10.1038/ijo.2010.146 · Cited by 34 · see citing works

Promoter region of the bovine growth hormone receptor gene: Single nucleotide polymorphism discovery in cattle and association with performance in Brangus bulls1

Garrett, A. J., Rincón, G., Medrano, J. F. F., Elzo, M. A., Silver, G. A., & Thomas, M. G. (2008) · Journal of Animal Science · doi:10.2527/jas.2008-0990 · Cited by 34 · see citing works

Levels of human platelet-derived soluble CD40 ligand depend on haplotypes of CD40LG-CD40-ITGA2

Aloui, C., Prigent, A., Tariket, S., Sut, C., Fagan, J., Cognasse, F., Chakroun, T., Garraud, O., & Laradi, S. (2016) · Scientific Reports · doi:10.1038/srep24715 · Cited by 33 · see citing works

Variation in oxytocin receptor gene (OXTR) polymorphisms is associated with emotional and behavioral reactions to betrayal

Tabak, B. A., McCullough, M. E., Carver, C. S., Pedersen, E. J., & Cuccaro, M. L. (2013) · Social Cognitive and Affective Neuroscience · doi:10.1093/scan/nst042 · Cited by 33 · see citing works

The Interaction between Childhood Bullying and the FKBP5 Gene on Psychotic-Like Experiences and Stress Reactivity in Real Life

Cristóbal-Narváez, P., Sheinbaum, T., Rosa, A., Ballespí, S., de Castro-Català, M., Peña, E., Kwapil, T. R., & Barrantes‐Vidal, N. (2016) · PLoS ONE · doi:10.1371/journal.pone.0158809 · Cited by 32 · see citing works

On the origin and structure of haplotype blocks

Shipilina, D., Pal, A., Stankowski, S., Chan, Y. F., & Barton, N. (2022) · Molecular Ecology · doi:10.1111/mec.16793 · Cited by 31 · see citing works

Genotype and haplotype analysis of TP53 gene and the risk of pancreatic cancer: an association study in the Czech Republic

Naccarati, A., Pardini, B., Vymetalkova, V. P., Šmerhovský, Z., Vodičková, Ľ., Souček, P., Vrána, D., Holcátová, I., Ryska, M., & Vodička, P. (2010) · Carcinogenesis · doi:10.1093/carcin/bgq032 · Cited by 32 · see citing works

Matrix metalloproteinase-9 genotypes and haplotypes are associated with multiple sclerosis and with the degree of disability of the disease

Fernandes, K., Brum, D. G., Sandrim, V. C., Guerreiro, C. T., Barreira, A. A., & Tanus-Santos, J. E. (2009) · Journal of Neuroimmunology · doi:10.1016/j.jneuroim.2009.07.004 · Cited by 31 · see citing works

Estimating Haplotype Frequency and Coverage of Databases

Egeland, T., & Salas, A. (2008) · PLoS ONE · doi:10.1371/journal.pone.0003988 · Cited by 31 · see citing works

Endothelial nitric oxide synthase tagSNPs influence the effects of enalapril in essential hypertension

Oliveira‐Paula, G. H., Lacchini, R., Luizon, M. R., Fontana, V., Silva, P. S., Biagi, C., & Tanus-Santos, J. E. (2016) · Nitric Oxide · doi:10.1016/j.niox.2016.03.006 · Cited by 31 · see citing works

Diet-Gene Interactions Underlie Metabolic Individuality and Influence Brain Development: Implications for Clinical Practice Derived from Studies on Choline Metabolism

Zeisel, S. H. (2012) · Annals of Nutrition and Metabolism · doi:10.1159/000337310 · Cited by 30 · see citing works

Analysis of the Role of Interleukin 6 Receptor Haplotypes in the Regulation of Circulating Levels of Inflammatory Biomarkers and Risk of Coronary Heart Disease

Gigante, B., Strawbridge, R. J., Velásquez, I. M., Golabkesh, Z., Silveira, A. M. V., Goel, A., Baldassarre, D., Veglia, F., Tremoli, E., Clarke, R., et al. (2015) · PLoS ONE · doi:10.1371/journal.pone.0119980 · Cited by 30 · see citing works

Aldehyde dehydrogenase 2 genetic variations may increase susceptibility to Parkinson's disease in Han Chinese population

Zhang, X., Ye, Y.-L., Wang, Y.-N., Liu, F., Liu, X., Hu, B., Zou, M., & Zhu, J. (2015) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2015.06.001 · Cited by 29 · see citing works

Endothelial Nitric Oxide Synthase Haplotypes Associated with Hypertension Do Not Predispose to Cardiac Hypertrophy

Vasconcellos, V. B., Lacchini, R., Jacob‐Ferreira, A. L., Sales, M. L., Ferreira-Sae, M. C., Schreiber, R., Nadruz, W., & Tanus-Santos, J. E. (2010) · DNA and Cell Biology · doi:10.1089/dna.2009.0955 · Cited by 29 · see citing works

SLC30A8 (ZnT8) variations and type 2 diabetes in the Chinese Han population

Xu, J., Wang, J., & Chen, B. (2012) · Genetics and Molecular Research · doi:10.4238/2012.may.24.1 · Cited by 29 · see citing works

Identification of Base Pairs in Single-Nucleotide Polymorphisms by MutS Protein-Mediated Capillary Electrophoresis

Drabovich, A. P., & Krylov, S. N. (2006) · Analytical Chemistry · doi:10.1021/ac0520386 · Cited by 28 · see citing works

Single nucleotide polymorphism in the MMP-9 gene is associated with susceptibility to develop multiple sclerosis in an Italian case-control study

Russa, A. L., Cittadella, R., Marco, E. V. D., Valentino, P., Andreoli, V., Trecroci, F., Latorre, V., Gambardella, A., & Quattrone, A. (2010) · Journal of Neuroimmunology · doi:10.1016/j.jneuroim.2010.04.016 · Cited by 28 · see citing works

Association of Endothelial Nitric Oxide Synthase Gene Polymorphisms (894G/T, −786T/C, G10T) and Clinical Findings in Patients with Migraine

Eröz, R., Bahadir, A., Dikici, S., & Taşdemir, Ş. (2014) · Neuromolecular medicine · doi:10.1007/s12017-014-8311-0 · Cited by 29 · see citing works

Involvement of genetic factors and lifestyle on the occurrence of colorectal and gastric cancer

Baroudi, O., & Elgaaïed, A. B. A. (2016) · Critical Reviews in Oncology/Hematology · doi:10.1016/j.critrevonc.2016.08.014 · Cited by 28 · see citing works

Gene–Gene Interactions Among PRKCA, NOS3 and BDKRB2 Polymorphisms Affect the Antihypertensive Effects of Enalapril

Oliveira‐Paula, G. H., Luizon, M. R., Lacchini, R., Fontana, V., Silva, P. S., Biagi, C., & Tanus-Santos, J. E. (2016) · Basic & Clinical Pharmacology & Toxicology · doi:10.1111/bcpt.12682 · Cited by 28 · see citing works

Association of haplotypes in the IL8 gene with susceptibility to chronic periodontitis in a Brazilian population

Kim, Y. J., Viana, A. C., Curtis, K. M. C., Orrico, S. R. P., Cirelli, J. A., Mendes‐Junior, C. T., & Scarel‐Caminaga, R. M. (2010) · Clinica Chimica Acta · doi:10.1016/j.cca.2010.05.014 · Cited by 27 · see citing works

Homogeneous and one-step fluorescent allele-specific PCR for SNP genotyping assays using conjugated polyelectrolytes

Duan, X., Liu, L., & Wang, S. (2008) · Biosensors and Bioelectronics · doi:10.1016/j.bios.2008.10.027 · Cited by 26 · see citing works

Summer Term

Satya, R. V., Professor, M., Mukherjee, A., & Satya, C. R. V. (2015)

Latest HapMap Update Aims to Direct Researchers to Genetic Basis of Disease

Schmidt, C. (2005) · JNCI Journal of the National Cancer Institute · doi:10.1093/jnci/dji420 · Cited by 4 · see citing works

Genotype and Epigenotype by Single Nucleotide Polymorphism (SNP) Analysis

Gunderson, K. L., Barker, D. L. A., Bibikova, M. V., & Fan, J. (2007) · Elsevier eBooks · doi:10.1016/b978-012370465-8/50012-0 · Cited by 2 · see citing works

Am. J. Hum. Genet. 77:988–998, 2005 The Effect of Single-Nucleotide Polymorphism Marker Selection on Patterns of Haplotype Blocks and Haplotype Frequency Estimates

Nothnagel, M., & Rohde, K. (2013)

The Structure of Haplotype Blocks in the Human Genome

Gabriel, S. B., Schaffner, S. F., Nguyen, H., Moore, J. M., Roy, J., Blumenstiel, B., Higgins, J., DeFelice, M., Lochner, A., Faggart, M., et al. (2002) · Science · doi:10.1126/science.1069424 · Cited by 5,863 · see citing works