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The Chromosome of Escherichia coli
Abstract
Autoradiography of Escherichia coli, labeled with tritiated thymidine and lysed with duponol, has shown that the bacterial chromosome comprises a single piece of DNA which is probably duplicated at a single growing point (Cairns, 1963). Further, it seemed likely from the variety of structures seen that this DNA is in the form of a circle while it is being replicated, even though no intact replicating circles had, at that time, been found.
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Citations
Cited by
The Determination of Molecular Weight of Bacterial Genome DNA from Renaturation Rates
Gillis, M., Ley, J. D., & Cleene, M. D. (1970) · European Journal of Biochemistry · doi:10.1111/j.1432-1033.1970.tb00831.x · Cited by 431
Visualization of Bacterial Genes in Action
Miller, O. L., Hamkalo, B. A., & Thomas, C. A. (1970) · Science · doi:10.1126/science.169.3943.392 · Cited by 375
Bridges, B. A., & Mottershead, R. (1971) · Mutation Research · doi:10.1016/0027-5107(71)90120-5 · Cited by 67
(1967) · doi:10.1016/s0079-6603(08)60951-4 · Cited by 48
Kidoaki, S., & Yoshikawa, K. (1999) · Biophysical Chemistry · doi:10.1016/s0301-4622(98)00231-2 · Cited by 33
Metadata
- Authors
- Cairns, J.
- Venue
- Cold Spring Harbor Symposia on Quantitative Biology
- Publisher
- Cold Spring Harbor Laboratory
- Published
- 1963-01-01
- Volume
- 28
- Issue
- 0
- Pages
- 43-46
- ISSN
- 0091-7451 (ISSN-L)
- 1943-4456
- OpenAlex
- W2324550162
- Cited by
- 409
- References
- 0
- Type
- posted content
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: The Chromosome of Escherichia coli. https://app.cochat.ai/papers/10.1101/sqb.1963.028.01.011
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- Cairns, J. (1963). The Chromosome of Escherichia coli. Cold Spring Harbor Symposia on Quantitative Biology. https://doi.org/10.1101/sqb.1963.028.01.011
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
