RecA+-dependent mutagenesis occurring before DNA replication in UV- and -γ irradiated Escherichia coli
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Closely opposing lesions may contribute to explaining that in wild-type yeast and bacteria most UV-induced mutagenesis depends on functional NER and occurs in G1, while without NER mutagenesis is S-phase specific.
“These particular lesions may also contribute to explain the observation that both in wild-type yeast and bacteria cells most of the UV-induced mutagenesis depends upon a functional NER and takes place in G1 cells, while in the absence of NER the mutagenesis is S-phase specific [80,81].”
From Mind the gap: keeping UV lesions in check (2011) · cites this paper as [81]
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- Authors
- Bridges, B. A., & Mottershead, R.
- Affiliations
- University of Sussex (GB)
- Venue
- Mutation Research
- Publisher
- Elsevier BV
- Published
- 1971-09
- Volume
- 13
- Issue
- 1
- Pages
- 1-8
- ISSN
- 0027-5107 (ISSN-L)
- OpenAlex
- W2056393864
- Cited by
- 67
- References
- 25
- Citations by year
- 2021: 1 · 2017: 1 · 2015: 2 · 2014: 1
- FWCI
- 1.17
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Mutation research. Fundamental and molecular mechanisms of mutagenesis (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › DNA Repair Mechanisms
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Bacterial Genetics and Biotechnology
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Cancer Research › Carcinogens and Genotoxicity Assessment
- Keywords
- UV mutagenesis, gamma-ray mutagenesis, Escherichia coli, uvrA, photoreversibility, streptomycin resistance, DNA excision, homologous recombination, DNA replication
- MeSH terms
- Cell Count, Cell Survival, DNA Replication, DNA, Bacterial, Drug Resistance, Microbial, Escherichia coli, Genetics, Microbial, Light, Mutation, Radiation Genetics, Recombination, Genetic, Streptomycin, Time Factors, Ultraviolet Rays
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