Molecular Biology of Neuronal Geometry: Expression of Neurofilament Genes Influences Axonal Diameter

Local modulation of neurofilament phosphorylation, axonal caliber, and slow axonal transport by myelinating Schwann cells

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Neurofilament gene expression: a major determinant of axonal caliber.

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Neurofilaments as biomarkers in neurological disorders — towards clinical application

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Intermediate filaments mediate cytoskeletal crosstalk

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Kinesin mutations cause motor neuron disease phenotypes by disrupting fast axonal transport in Drosophila

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Immunocytochemical localization of tubulin and microtubule-associated protein 2 during the development of hippocampal neurons in culture

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Neurofilament-deficient axons and perikaryal aggregates in viable transgenic mice expressing a neurofilament-β-galactosidase fusion protein

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Phosphorylation on carboxyl terminus domains of neurofilament proteins in retinal ganglion cell neurons in vivo: influences on regional neurofilament accumulation, interneurofilament spacing, and axon caliber.

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Presence or absence of TrKA protein distinguishes subsets of small sensory neurons with unique cytochemical characteristics and dorsal horn projections

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Axotomy-induced alterations in the electrophysiological characteristics of neurons

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Alpha-internexin, a novel neuronal intermediate filament protein, precedes the low molecular weight neurofilament protein (NF-L) in the developing rat brain

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Multiple fates of newly synthesized neurofilament proteins: evidence for a stationary neurofilament network distributed nonuniformly along axons of retinal ganglion cell neurons.

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Myelination Is Altered in Insulin-Like Growth Factor-I Null Mutant Mice

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Neurofilament deficiency in quail caused by nonsense mutation in neurofilament-L gene.

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Protein synthesis in axons and terminals: significance for maintenance, plasticity and regulation of phenotype

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Absence of the Mid-sized Neurofilament Subunit Decreases Axonal Calibers, Levels of Light Neurofilament (NF-L), and Neurofilament Content

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Functions of intermediate filaments

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The cellular neurobiology of neuronal development: The cerebellar granule cell

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The Molecular Biology of Intermediate Filament Proteins

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Single-cell analysis of sodium channel expression in dorsal root ganglion neurons

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Altered slow axonal transport and regeneration in a myelin-deficient mutant mouse: the trembler as an in vivo model for Schwann cell-axon interactions

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Axotomy-induced changes in the expression of a type III neuronal intermediate filament gene

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Axotomy-induced alterations in the synthesis and transport of neurofilaments and microtubules in dorsal root ganglion cells

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Role of insulin-like growth factors in peripheral nerve regeneration

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Cytotypic differences in the protein composition of the axonally transported cytoskeleton in mammalian neurons

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Structure and evolutionary origin of the gene encoding mouse NF-M, the middle-molecular-mass neurofilament protein

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Effects of advancing age on peripheral nerve regeneration

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Differential regulation of peripherin and neurofilament gene expression in regenerating rat DRG neurons

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Axonal cytoskeletal changes after non-disruptive axonal injury

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Retardation in the slow axonal transport of cytoskeletal elements during maturation and aging

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Two distinct functions of the carboxyl-terminal tail domain of NF-M upon neurofilament assembly: cross-bridge formation and longitudinal elongation of filaments.

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Differential turnover of phosphate groups on neurofilament subunits in mammalian neurons in vivo.

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A Role for Intermediate Filaments in Determining and Maintaining the Shape of Nerve Cells

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Modulation of axon diameter and neurofilaments by hypomyelinating Schwann cells in transgenic mice

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In Vivo Phosphorylation of Distinct Domains of the 70-Kilodalton Neurofilament Subunit Involves Different Protein Kinases

Sihag, R. K., & Nixon, R. A. (1989) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(17)31280-2 · Cited by 109 · see citing works

Function and Evolution of Neurofilament Proteinsa

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A comparison of peripheral and central axotomy effects on neurofilament and tubulin gene expression in rat dorsal root ganglion neurons

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Neurofilament antibodies and spiral ganglion neurons of the mammalian cochlea

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The complete amino acid sequence of the major mammalian neurofilament protein (NF‐L)

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Effects of insulin and insulin-like growth factors on neurofilament mRNA and tubulin mRNA content in human neuroblastoma SH-SY5Y cells

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Some neural intermediate filaments contain both peripherin and the neurofilament proteins

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Slow axonal transport mechanisms move neurofilaments relentlessly in mouse optic axons.

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Age-Related Atrophy of Motor Axons in Mice Deficient in the Mid-Sized Neurofilament Subunit

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Properties of highly viscous gels formed by neurofilaments in vitro. A possible consequence of a specific inter-filament cross-bridging

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Changes in neurofilament gene expression occur after axotomy of dorsal root ganglion neurons: Anin situ hybridization study

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NuMA is a component of an insoluble matrix at mitotic spindle poles

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Neurofilament protein synthesis in DRG neurons decreases more after peripheral axotomy than after central axotomy

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Axonal cytoskeleton at the nodes of Ranvier

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Structure of the gene for the neuronal intermediate filament protein alpha-internexin and functional analysis of its promoter.

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Sprouts emerging from the dendrites of axotomized lamprey central neurons have axonlike ultrastructure

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Spastic Paraplegia Mutation N256S in the Neuronal Microtubule Motor KIF5A Disrupts Axonal Transport in a Drosophila HSP Model

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Phosphorylation‐Dependent Immunoreactivity of Neurofilaments and the Rate of Slow Axonal Transport in the Central and Peripheral Axons of the Rat Dorsal Root Ganglion

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Intermediate filaments in muscle and epithelial cells of nematodes.

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Intermediate filaments in non-neuronal cells of invertebrates: isolation and biochemical characterization of intermediate filaments from the esophageal epithelium of the mollusc Helix pomatia.

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Interneurons versus efferent neurons: Heterogeneity in their neurite outgrowth response to glia from several brain regions

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Immunohistochemical and ultrastructural observations on homer wright (neuroblastic) rosettes and the “pale islands” of human cerebellar medulloblastomas

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The 2022 Lady Estelle Wolfson lectureship on neurofilaments

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Anti-neurofilament protein antibodies in opsoclonus-myoclonus

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A review of intermediate filament biology and their use in pathologic diagnosis

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Molecular mechanisms of diketone neurotoxicity

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Carbon disulfide axonopathy. Another experimental model characterized by acceleration of neurofilament transport and distinct changes of axonal size

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Non-phosphorylated and phosphorylated neurofilaments in the cerebellum of the rat: an immunocytochemical study using monoclonal antibodies. Development in normal and thyroid-deficient animals

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Axotomy accelerates slow component b of axonal transport

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The role of NMDA receptors in the slow neuronal degeneration of Parkinson's disease

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Structural Aspects of Intermediate Filaments

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Different posttranscriptional controls for the human neurofilament light and heavy genes in transgenic mice

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Developmental patterns of intermediate filament gene expression in the normal hamster brain

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Mice overexpressing the human neurofilament heavy gene as a model of ALS

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Long-term changes in synthesis of intermediate filament protein, actin and other proteins in pleural sensory neurons of Aplysia produced by an in vitro analogue of sensitization training

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An immunocytochemical and biochemical study of the microtubule-associated protein Tau during post-lesion afferent reorganization in the hippocampus of adult rats

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Embryonic and regenerating Xenopus retinal fibers are intrinsically different

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Differential turnover of tubulin and neurofilament proteins in central nervous system neuron terminals

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Dynamics of mammalian high‐molecular‐weight neurofilament subunit phosphorylation in cultured rat sympathetic neurons

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Hypothyroidism reduces the rate of slow component a (SCa) axonal transport and the amount of transported tubulin in the hyt/hyt mouse optic nerve

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Monoclonal antibodies against plant proteins recognise animal intermediate filaments

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Developmental changes in phosphorylation state of neurofilament proteins in the chick embryonic optic nerve

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Chromatin structure and gene expression in Alzheimer's disease

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Neurofilaments are prominent in bullfrog olfactory axons but are rarely seen in those of the tiger salamander, Ambystoma tigrinum

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Recovery of tail-elicited siphon-withdrawal reflex following unilateral axonal injury is associated with ipsi- and contralateral changes in gene expression in Aplysia californica

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Interaction of multiple nuclear proteins with the promoter region of the mouse 68‐kDa neurofilament gene

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Active electrophysiological properties of spinal motoneurons in aged cats following axotomy

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Regulation of neurofilament L, M and H gene expression during retinoic acid-induced neural differentiation of P19 embryonal carcinoma cells

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Expression of Schwann cell-specific proteins and low-molecular-weight neurofilament protein during regeneration of sciatic nerve treated with neurotrophin-4

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Calcium‐activated proteolysis of neurofilament proteins in goldfish Mauthner axons

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Biochemical composition and dynamics of the axonal cytoskeleton in the corticospinal system of the adult hamster

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Effect of neurotrophin‐3 on reinnervation of the larynx using the phrenic nerve transfer technique

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Passive electrical properties of motoneurons in aged cats following axotomy

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The cerebral neurons of Helix aspersa during hibernation. Changes in the cytochemical detection of calmodulin, cytoskeletal components and phosphatases

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Calibre and Microtubule Content of the Non‐Medullated and Myelinated Domains of Optic Nerve Axons of Rats

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Transient and Persistent Depolarization‐Induced Changes of Protein Phosphorylation in a Molluscan Nervous System

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Increased slow transport in axons of regenerating newt limbs after a nerve conditioning lesion

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Long‐Term Effects of Axotomy on β‐Tubulin and NF Gene Expression in Rat DRG Neurons

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The role of neurofilament transport in the radial growth of myelinated axons

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