The DOI matches its Crossref record; 39 of the 39 references it cites were found in a registry or an index.
Thermodynamic Uncertainty Relation for Biomolecular Processes
Open accessAbstract
Biomolecular systems like molecular motors or pumps, transcription and translation machinery, and other enzymatic reactions, can be described as Markov processes on a suitable network. We show quite generally that, in a steady state, the dispersion of observables, like the number of consumed or produced molecules or the number of steps of a motor, is constrained by the thermodynamic cost of generating it. An uncertainty ε requires at least a cost of 2k(B)T/ε2 independent of the time required to generate the output.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Stochastic thermodynamics, fluctuation theorems and molecular machines
Seifert, U. (2012) · Reports on Progress in Physics · doi:10.1088/0034-4885/75/12/126001 · Cited by 3,300
Self-citationStochastic Processes in Physics and Chemistry
Cercignani, C. (2005) · Encyclopedia of Condensed Matter Physics · doi:10.1016/b0-12-369401-9/00623-9 · Cited by 2,139
Direct observation of kinesin stepping by optical trapping interferometry
Svoboda, K., Schmidt, C. F., Schnapp, B. J., & Block, S. M. (1993) · Nature · doi:10.1038/365721a0 · Cited by 1,910
A Gallavotti–Cohen-Type Symmetry in the Large Deviation Functional for Stochastic Dynamics
Lebowitz, J. L., & Spohn, H. (1999) · Journal of Statistical Physics · doi:10.1023/a:1004589714161 · Cited by 1,417
Recent Advances in Optical Tweezers
Moffitt, J. R., Chemla, Y. R., Smith, S. B., & Bustamante, C. (2008) · Annual Review of Biochemistry · doi:10.1146/annurev.biochem.77.043007.090225 · Cited by 1,084
Molecular Motors: A Theorist's Perspective
Kolomeisky, A. B., & Fisher, M. E. (2007) · Annual Review of Physical Chemistry · doi:10.1146/annurev.physchem.58.032806.104532 · Cited by 575
High-Resolution, Single-Molecule Measurements of Biomolecular Motion
Greenleaf, W. J., Woodside, M. T., & Block, S. M. (2007) · Annual Review of Biophysics and Biomolecular Structure · doi:10.1146/annurev.biophys.36.101106.101451 · Cited by 462
The energy–speed–accuracy trade-off in sensory adaptation
Lan, G., Sartori, P., Neumann, S., Sourjik, V., & Tu, Y. (2012) · Nature Physics · doi:10.1038/nphys2276 · Cited by 452
Physical limits to biochemical signaling
Bialek, W., & Setayeshgar, S. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0504321102 · Cited by 443
Velocity and diffusion constant of a periodic one-dimensional hopping model
Derrida, B. (1983) · Journal of Statistical Physics · doi:10.1007/bf01019492 · Cited by 400
Cited by
Irreversible entropy production: From classical to quantum
Landi, G. T., & Paternostro, M. (2021) · Reviews of Modern Physics · doi:10.1103/revmodphys.93.035008 · Cited by 384
Dissipative adaptation in driven self-assembly
England, J. L. (2015) · Nature Nanotechnology · doi:10.1038/nnano.2015.250 · Cited by 304
Escapement mechanisms and the conversion of disequilibria; the engines of creation
Branscomb, E., Biancalani, T., Goldenfeld, N., & Russell, M. (2017) · Physics Reports · doi:10.1016/j.physrep.2017.02.001 · Cited by 96
(2023) · doi:10.1016/j.isci.2023.108740 · Cited by 1
Metadata
- Authors
- Barato, A. C., & Seifert, U.
- Venue
- Physical Review Letters
- Publisher
- American Physical Society (APS)
- Published
- 2015-04-15
- Volume
- 114
- Issue
- 15
- Pages
- 158101-158101
- ISSN
- 0031-9007 (ISSN-L)
- 1079-7114
- OpenAlex
- W2078695144
- Cited by
- 957
- References
- 39
- FWCI
- 23.73
- Type
- journal article
- Language
- en
- Open access
- green
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Thermodynamic Uncertainty Relation for Biomolecular Processes. https://app.cochat.ai/papers/10.1103/physrevlett.114.158101
- The paper
- Barato, A. C., & Seifert, U. (2015). Thermodynamic Uncertainty Relation for Biomolecular Processes. Physical Review Letters. https://doi.org/10.1103/physrevlett.114.158101
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.