The DOI matches its Crossref record; 112 of the 112 references it cites were found in a registry or an index.
High-Resolution, Single-Molecule Measurements of Biomolecular Motion
Open accessAbstract
Many biologically important macromolecules undergo motions that are essential to their function. Biophysical techniques can now resolve the motions of single molecules down to the nanometer scale or even below, providing new insights into the mechanisms that drive molecular movements. This review outlines the principal approaches that have been used for high-resolution measurements of single-molecule motion, including centroid tracking, fluorescence resonance energy transfer, magnetic tweezers, atomic force microscopy, and optical traps. For each technique, the principles of operation are outlined, the capabilities and typical applications are examined, and various practical issues for implementation are considered. Extensions to these methods are also discussed, with an eye toward future application to outstanding biological problems.
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Cites
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Metadata
- Authors
- Greenleaf, W. J., Woodside, M. T., & Block, S. M.
- Venue
- Annual Review of Biophysics and Biomolecular Structure
- Publisher
- Annual Reviews
- Published
- 2007-06-01
- Volume
- 36
- Issue
- 1
- Pages
- 171-190
- ISSN
- 1056-8700 (ISSN-L)
- 1545-4266
- OpenAlex
- W2114229182
- Cited by
- 462
- References
- 112
- FWCI
- 21.41
- Type
- journal article
- Language
- en
- Open access
- green
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- Greenleaf, W. J., Woodside, M. T., & Block, S. M. (2007). High-Resolution, Single-Molecule Measurements of Biomolecular Motion. Annual Review of Biophysics and Biomolecular Structure. https://doi.org/10.1146/annurev.biophys.36.101106.101451
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
