The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Localized Single-Stranded Bubble Mechanism for Cyclization of Short Double Helix DNA
Abstract
Recent experiments indicate that double-stranded DNA molecules of approximately 100 base pairs in length have a probability of cyclization which is up to 10(5) times larger than that expected based on the known bending modulus of the double-helix. We argue that for short molecules, the formation of a few base pairs of single-stranded DNA can provide a "flexible hinge" that facilitates loop formation. A detailed calculation shows that this mechanism explains the experimental data.
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Mathews, D. H., Sabina, J., Zuker, M., & Turner, D. H. (1999) · Journal of Molecular Biology · doi:10.1006/jmbi.1999.2700 · Cited by 3,795
Cited by
Extreme Bendability of DNA Less than 100 Base Pairs Long Revealed by Single-Molecule Cyclization
Vafabakhsh, R., & Ha, T. (2012) · Science · doi:10.1126/science.1224139 · Cited by 301
Inferring spatially varying bending stiffness of biopolymers with deep-learning approach
Hong, C., Lim, C., Oh, J., Lee, J.-B., Jeong, E. E., Yoo, J.-Y., Kim, W. K., & Jeon, J.-H. (2025) · Machine Learning: Science and Technology · doi:10.1088/2632-2153/ae1a35
Metadata
- Authors
- Yan, J., & Marko, J. F.
- Venue
- Physical Review Letters
- Publisher
- American Physical Society (APS)
- Published
- 2004-09-03
- Volume
- 93
- Issue
- 10
- Pages
- 108108-108108
- ISSN
- 0031-9007 (ISSN-L)
- 1079-7114
- OpenAlex
- W2033763942
- Cited by
- 261
- References
- 1
- FWCI
- 6.01
- Type
- journal article
- Language
- en
- Open access
- closed
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- Yan, J., & Marko, J. F. (2004). Localized Single-Stranded Bubble Mechanism for Cyclization of Short Double Helix DNA. Physical Review Letters. https://doi.org/10.1103/physrevlett.93.108108
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