The DOI matches its Crossref record; 98 of the 98 references it cites were found in a registry or an index.
Cellular Response of Pea Plants to Cadmium Toxicity: Cross Talk between Reactive Oxygen Species, Nitric Oxide, and Calcium
Open accessAbstract
Cadmium (Cd) toxicity has been widely studied in different plant species; however, the mechanism involved in its toxicity as well as the cell response against the metal have not been well established. In this work, using pea (Pisum sativum) plants, we studied the effect of Cd on antioxidants, reactive oxygen species (ROS), and nitric oxide (NO) metabolism of leaves using different cellular, molecular, and biochemical approaches. The growth of pea plants with 50 μ m CdCl2 affected differentially the expression of superoxide dismutase (SOD) isozymes at both transcriptional and posttranscriptional levels, giving rise to a SOD activity reduction. The copper/zinc-SOD down-regulation was apparently due to the calcium (Ca) deficiency induced by the heavy metal. In these circumstances, the overproduction of the ROS hydrogen peroxide and superoxide could be observed in vivo by confocal laser microscopy, mainly associated with vascular tissue, epidermis, and mesophyll cells, and the production of superoxide radicals was prevented by exogenous Ca. On the other hand, the NO synthase-dependent NO production was strongly depressed by Cd, and treatment with Ca prevented this effect. Under these conditions, the pathogen-related proteins PrP4A and chitinase and the heat shock protein 71.2, were up-regulated, probably to protect cells against damages induced by Cd. The regulation of these proteins could be mediated by jasmonic acid and ethylene, whose contents increased by Cd treatment. A model is proposed for the cellular response to long-term Cd exposure consisting of cross talk between Ca, ROS, and NO.
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Cited by
Reactive oxygen species and antioxidant machinery in abiotic stress tolerance in crop plants
Gill, S. S., & Tuteja, N. (2010) · Plant Physiology and Biochemistry · doi:10.1016/j.plaphy.2010.08.016 · Cited by 11,663
Cadmium toxicity in plants: Impacts and remediation strategies
Haider, F. U., Liqun, C., Coulter, J. A., Cheema, S. A., Wu, J., Zhang, R., Wenjun, M., & Farooq, M. (2021) · Ecotoxicology and Environmental Safety · doi:10.1016/j.ecoenv.2020.111887 · Cited by 1,541
Unravelling cadmium toxicity and tolerance in plants: Insight into regulatory mechanisms
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Cadmium stress in plants: A critical review of the effects, mechanisms, and tolerance strategies
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Parrotta, L. (2015) · Frontiers in Plant Science · doi:10.3389/fpls.2015.00133 · Cited by 438
Metadata
- Authors
- Rodríguez-Serrano, M., Romero-Puertas, M. C., Pazmiño, D. M., Testillano, P. S., Risueño, M. C., del Río, L. A., & Sandalio, L. M.
- Venue
- Plant Physiology
- Publisher
- Oxford University Press (OUP)
- Published
- 2009-03-11
- Volume
- 150
- Issue
- 1
- Pages
- 229-243
- ISSN
- 0032-0889 (ISSN-L)
- 1532-2548
- OpenAlex
- W2108283825
- Cited by
- 621
- References
- 98
- FWCI
- 47.23
- Type
- journal article
- Language
- en
- Open access
- hybrid
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- Rodríguez-Serrano, M., Romero-Puertas, M. C., Pazmiño, D. M., Testillano, P. S., Risueño, M. C., del Río, L. A., & Sandalio, L. M. (2009). Cellular Response of Pea Plants to Cadmium Toxicity: Cross Talk between Reactive Oxygen Species, Nitric Oxide, and Calcium. Plant Physiology. https://doi.org/10.1104/pp.108.131524
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