The DOI matches its Crossref record; 44 of the 44 references it cites were found in a registry or an index.
The Rice Aquaporin Lsi1 Mediates Uptake of Methylated Arsenic Species
Open accessAbstract
Pentavalent methylated arsenic (As) species such as monomethylarsonic acid [MMA(V)] and dimethylarsinic acid [DMA(V)] are used as herbicides or pesticides, and can also be synthesized by soil microorganisms or algae through As methylation. The mechanism of MMA(V) and DMA(V) uptake remains unknown. Recent studies have shown that arsenite is taken up by rice (Oryza sativa) roots through two silicon transporters, Lsi1 (the aquaporin NIP2;1) and Lsi2 (an efflux carrier). Here we investigated whether these two transporters also mediate the uptake of MMA(V) and DMA(V). MMA(V) was partly reduced to trivalent MMA(III) in rice roots, but only MMA(V) was translocated to shoots. DMA(V) was stable in plants. The rice lsi1 mutant lost about 80% and 50% of the uptake capacity for MMA(V) and DMA(V), respectively, compared with the wild-type rice, whereas Lsi2 mutation had little effect. The short-term uptake kinetics of MMA(V) can be described by a Michaelis-Menten plus linear model, with the wild type having 3.5-fold higher V max than the lsi1 mutant. The uptake kinetics of DMA(V) were linear with the slope being 2.8-fold higher in the wild type than the lsi1 mutant. Heterologous expression of Lsi1 in Xenopus laevis oocytes significantly increased the uptake of MMA(V) but not DMA(V), possibly because of a very limited uptake of the latter. Uptake of MMA(V) and DMA(V) by wild-type rice was increased as the pH of the medium decreased, consistent with an increasing proportion of the undissociated species. The results demonstrate that Lsi1 mediates the uptake of undissociated methylated As in rice roots.
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Cites
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Self-citationWorldwide Occurrences of Arsenic in Ground Water
Nordstrom, D. K. (2002) · Science · doi:10.1126/science.1072375 · Cited by 1,622
Transporters of arsenite in rice and their role in arsenic accumulation in rice grain
Ma, J. F., Yamaji, N., Mitani, N., Xu, X.-Y., Su, Y.-H., McGrath, S. P., & Zhao, F.-J. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0802361105 · Cited by 1,411
Self-citationPlant Aquaporins: Membrane Channels with Multiple Integrated Functions
Maurel, C., Verdoucq, L., Luu, D.-T., & Santoni, V. (2008) · Annual Review of Plant Biology · doi:10.1146/annurev.arplant.59.032607.092734 · Cited by 1,280
Arsenic uptake and metabolism in plants
Zhao, F. J., Ma, J. F., Meharg, A. A., & McGrath, S. P. (2009) · New Phytologist · doi:10.1111/j.1469-8137.2008.02716.x · Cited by 1,185
Self-citationAn efflux transporter of silicon in rice
Ma, J. F., Yamaji, N., Mitani, N., Tamai, K., Konishi, S., Fujiwara, T., Katsuhara, M., & Yano, M. (2007) · Nature · doi:10.1038/nature05964 · Cited by 927
Self-citationWilliams, P. N., Villada, A., Deacon, C., Raab, A., Figuerola, J., Green, A. J., Feldmann, J., & Meharg, A. A. (2007) · Environmental Science & Technology · doi:10.1021/es070627i · Cited by 777
Self-citationGeographical Variation in Total and Inorganic Arsenic Content of Polished (White) Rice
Meharg, A. A., Williams, P. N., Adomako, E., Lawgali, Y. Y., Deacon, C., Villada, A., Cambell, R. C. J., Sun, G., Zhu, Y.-G., Feldmann, J., et al. (2009) · Environmental Science & Technology · doi:10.1021/es802612a · Cited by 772
Self-citationMonomethylarsonous Acid (MMAIII) Is More Toxic Than Arsenite in Chang Human Hepatocytes
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Growing Rice Aerobically Markedly Decreases Arsenic Accumulation
Xu, X. Y., McGrath, S. P., Meharg, A. A., & Zhao, F. J. (2008) · Environmental Science & Technology · doi:10.1021/es800324u · Cited by 664
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Cited by
Zhao, F.-J., McGrath, S. P., & Meharg, A. A. (2010) · Annual Review of Plant Biology · doi:10.1146/annurev-arplant-042809-112152 · Cited by 1,246
Self-citationToxic Heavy Metal and Metalloid Accumulation in Crop Plants and Foods
Clemens, S., & Ma, J. F. (2016) · Annual Review of Plant Biology · doi:10.1146/annurev-arplant-043015-112301 · Cited by 1,155
Self-citationArsenic Toxicity: The Effects on Plant Metabolism
Finnegan, P. M., & Chen, W. (2012) · Frontiers in Physiology · doi:10.3389/fphys.2012.00182 · Cited by 849
Arsenic and cadmium accumulation in rice and mitigation strategies
Zhao, F.-J., & Wang, P. (2020) · Plant and Soil · doi:10.1007/s11104-019-04374-6 · Cited by 624
Self-citationEarth Abides Arsenic Biotransformations
Zhu, Y.-G., Yoshinaga, M., Zhao, F.-J., & Rosen, B. P. (2014) · Annual Review of Earth and Planetary Sciences · doi:10.1146/annurev-earth-060313-054942 · Cited by 550
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Metadata
- Authors
- Li, R.-Y., Ago, Y., Liu, W.-J., Mitani, N., Feldmann, J., McGrath, S. P., Ma, J. F., & Zhao, F.-J.
- Venue
- Plant Physiology
- Publisher
- Oxford University Press (OUP)
- Published
- 2009-06-19
- Volume
- 150
- Issue
- 4
- Pages
- 2071-2080
- ISSN
- 0032-0889 (ISSN-L)
- 1532-2548
- OpenAlex
- W2146187577
- Cited by
- 414
- References
- 44
- FWCI
- 13.38
- Type
- journal article
- Language
- en
- Open access
- bronze
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- Li, R.-Y., Ago, Y., Liu, W.-J., Mitani, N., Feldmann, J., McGrath, S. P., Ma, J. F., & Zhao, F.-J. (2009). The Rice Aquaporin Lsi1 Mediates Uptake of Methylated Arsenic Species. Plant Physiology. https://doi.org/10.1104/pp.109.140350
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