Earth Abides Arsenic Biotransformations
Open accessAbstract
Arsenic is the most prevalent environmental toxic element and causes health problems throughout the world. The toxicity, mobility, and fate of arsenic in the environment are largely determined by its speciation, and arsenic speciation changes are driven, at least to some extent, by biological processes. In this article, biotransformation of arsenic is reviewed from the perspective of the formation of Earth and the evolution of life, and the connection between arsenic geochemistry and biology is described. The article provides a comprehensive overview of molecular mechanisms of arsenic redox and methylation cycles as well as other arsenic biotransformations. It also discusses the implications of arsenic biotransformation in environmental remediation and food safety, with particular emphasis on groundwater arsenic contamination and arsenic accumulation in rice.
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Exposure to iAs occurs as humans drink water enriched in As by natural geochemical processes or poor agricultural/manufacturing/mining practices and through the diet including from foods (e.g., rice) grown in contaminated soils.
“Exposure to iAs occurs as humans drink water enriched in As by natural geochemical processes or poor agricultural/manufacturing/mining practices and through the diet including from foods (e.g., rice) grown in contaminated soils (NRC 2013; Zhu et al. 2014; Li et al. 2016).”
From Algae as nutritional and functional food sources: revisiting our understanding. (2017) · cites this paper as Zhu et al. 2014
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Flagged first, then by citations
Research works printed but not linked: 2
- Meharg AA Zhao FJ 2012 Arsenic and Rice Dordrecht Springer
- Wenzel WW 2013 Arsenic Heavy Metals in Soils: Trace Metals and Metalloids in Soils and Their Bioavailability Alloway BJ 241 81 Dordrecht, Neth Springer
Cited by
Sorted by citations
Algae as nutritional and functional food sources: revisiting our understanding.
Wells, M. L., Potin, P., Craigie, J. S., Raven, J. A., Merchant, S. S., Helliwell, K. E., Smith, A. G., Camire, M. E., & Brawley, S. H. (2017) · Journal of Applied Phycology · doi:10.1007/s10811-016-0974-5 · Cited by 1,562 · see citing works
- Authors
- Zhu, Y.-G., Yoshinaga, M., Zhao, F.-J., & Rosen, B. P.
- Affiliations
- Chinese Academy of Sciences (CN)
- Department of Cellular Biology and Pharmacology, Herbert Wertheim College of Medicine, Florida International University, Miami, Florida 33199;
- College of Resources & Environmental Sciences, Nanjing Agricultural University, Nanjing 210095, People's Republic of China
- Florida International University (US)
- Venue
- Annual Review of Earth and Planetary Sciences
- Publisher
- Annual Reviews
- Published
- 2014-05-30
- Volume
- 42
- Issue
- 1
- Pages
- 443-467
- ISSN
- 0084-6597 (ISSN-L)
- 1545-4495
- PMC
- PMC4712701
- OpenAlex
- W2126473104
- Cited by
- 550
- References
- 174
- Citations by year
- 2026: 34 · 2025: 35 · 2024: 57 · 2023: 55 · 2022: 72 · 2021: 51 · 2020: 50 · 2019: 54 · 2018: 39 · 2017: 42 · 2016: 24 · 2015: 22 · 2014: 14 · 2012: 1
- FWCI
- 3.21
- Type
- journal article
- Language
- en
- Open access
- green
- doi.org
- Locations
- Annual Review of Earth and Planetary Sciences (publishedVersion)
- PubMed (publishedVersion)
- Rothamsted Repository (Rothamsted Repository) (acceptedVersion)
- PubMed Central (acceptedVersion)
- Research Center for Eco-Environmental Sciences OpenIR (Chinese Academy of Sciences) (submittedVersion)
- Rothamsted Repository (Rothamsted Repository) (submittedVersion)
- Funders
- National Natural Science Foundation of China (41330853, 41090282)
- Biotechnology and Biological Sciences Research Council (BB/F004087/1)
- National Institute of General Medical Sciences (R35GM136211, R01GM055425, R37GM055425)
- National Institute of Environmental Health Sciences (R01ES023779)
- Program for Changjiang Scholars and Innovative Research Team in University
- Topics
- Physical Sciences › Environmental Science › Environmental Chemistry › Arsenic contamination and mitigation
- Physical Sciences › Environmental Science › Health, Toxicology and Mutagenesis › Chromium effects and bioremediation
- Physical Sciences › Environmental Science › Pollution › Heavy metals in environment
- Keywords
- arsenic biotransformation, arsenic speciation, arsenic methylation, arsenic geochemistry, evolution of life, environmental remediation, food safety, groundwater arsenic contamination, ecotoxicity
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