Cited by 189Cassava research and cyanideSeed Germination and PhysiologyPlant nutrient uptake and metabolism

Mobilization and Utilization of Cyanogenic Glycosides: The Linustatin Pathway

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Selmar, Dirk, Lieberei, Reinhard, Biehl, Böle·1988·Plant Physiology

Abstract

In the seeds of Hevea brasiliensis, the cyanogenic monoglucoside linamarin (2-beta-d-glucopyranosyloxy-2-methylpropionitrile) is accumulated in the endosperm. After onset of germination, the cyanogenic diglucoside linustatin (2-[6-beta-d-glucosyl-beta-d-glucopyranosyloxy]-2- methylpropionitrile) is formed and exuded from the endosperm of Hevea seedlings. At the same time the content of cyanogenic monoglucosides decreases. The linustatin-splitting diglucosidase and the beta-cyanoalanine synthase that assimilates HCN, exhibit their highest activities in the young seedling at this time. Based on these observations the following pathway for the in vivo mobilization and metabolism of cyanogenic glucosides is proposed: storage of monoglucosides (in the endosperm)-glucosylation-transport of the diglucoside (out of the endosperm into the seedling)-cleavage by diglucosidase-reassimilation of HCN to noncyanogenic compounds. The presence of this pathway demonstrates that cyanogenic glucosides, typical secondary plant products serve in the metabolism of developing plants as N-storage compounds and do not exclusively exhibit protective functions due to their repellent effect.

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Crossref · 10.1104/pp.86.3.711

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Authors
Selmar, D., Lieberei, R., & Biehl, B.
Affiliations
Technische Universität Braunschweig (DE)
Venue
Plant Physiology
Published
1988-03-01
Volume
86
Issue
3
Pages
711-716
ISSN
  • 0032-0889 (ISSN-L)
  • 1532-2548
OpenAlex
W2015956911
Cited by
188
References
12
Citations by year
2026: 2 · 2025: 1 · 2024: 3 · 2023: 4 · 2022: 3 · 2021: 7 · 2020: 2 · 2019: 5 · 2018: 2 · 2017: 9 · 2016: 9 · 2015: 5 · 2014: 4 · 2013: 6 · 2012: 6
FWCI
6.88
Type
journal article
Language
en
Open access
Locations
  • PLANT PHYSIOLOGY (publishedVersion)
  • PubMed Central (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Life Sciences › Agricultural and Biological Sciences › Plant Science › Cassava research and cyanide
  • Life Sciences › Agricultural and Biological Sciences › Plant Science › Seed Germination and Physiology
  • Life Sciences › Agricultural and Biological Sciences › Plant Science › Plant nutrient uptake and metabolism
Keywords
cyanogenic glycosides, linamarin, Hevea brasiliensis, rubber tree seeds, seed germination, endosperm, β-cyanoalanine synthase, nitrogen storage, glucosylation, seedling development, secondary plant products

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