The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
The Chlamydomonas reinhardtii Plastid Chromosome
Open accessAbstract
Chlamydomonas reinhardtii is a unicellular eukaryotic alga possessing a single chloroplast that is widely used as a model system for the study of photosynthetic processes. This report analyzes the surprising structural and evolutionary features of the completely sequenced 203,395-bp plastid chromosome. The genome is divided by 21.2-kb inverted repeats into two single-copy regions of ∼80 kb and contains only 99 genes, including a full complement of tRNAs and atypical genes encoding the RNA polymerase. A remarkable feature is that >20% of the genome is repetitive DNA: the majority of intergenic regions consist of numerous classes of short dispersed repeats (SDRs), which may have structural or evolutionary significance. Among other sequenced chlorophyte plastid genomes, only that of the green alga Chlorella vulgaris appears to share this feature. The program MultiPipMaker was used to compare the genic complement of Chlamydomonas with those of other chloroplast genomes and to scan the genomes for sequence similarities and repetitive DNAs. Among the results was evidence that the SDRs were not derived from extant coding sequences, although some SDRs may have arisen from other genomic fragments. Phylogenetic reconstruction of changes in plastid genome content revealed that an accelerated rate of gene loss also characterized the Chlamydomonas/Chlorella lineage, a phenomenon that might be independent of the proliferation of SDRs. Together, our results reveal a dynamic and unusual plastid genome whose existence in a model organism will allow its features to be tested functionally.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Gene transfer to the nucleus and the evolution of chloroplasts
Martin, W., Stoebe, B., Goremykin, V., Hansmann, S., Hasegawa, M., & Kowallik, K. V. (1998) · Nature · doi:10.1038/30234 · Cited by 772
Ancestral chloroplast genome in Mesostigma viride reveals an early branch of green plant evolution
Lemieux, C., Otis, C., & Turmel, M. (2000) · Nature · doi:10.1038/35001059 · Cited by 277 · cited 4×
“The position of M. viride has been under debate, as evidence from different sources strongly supports either the Mesostigma land plants topology or the Mesostigma all green plants topology (Lemieux et al., 2000; Karol et al., 2001).”
BackgroundResultInfluential
Cited by
Lohse, M., Drechsel, O., & Bock, R. (2007) · Current Genetics · doi:10.1007/s00294-007-0161-y · Cited by 1,254
A Molecular Timeline for the Origin of Photosynthetic Eukaryotes
Yoon, H. S., Hackett, J. D., Ciniglia, C., Pinto, G., & Bhattacharya, D. (2004) · Molecular Biology and Evolution · doi:10.1093/molbev/msh075 · Cited by 945
The Importance of Energy Balance in Improving Photosynthetic Productivity
Kramer, D. M., & Evans, J. R. (2011) · Plant Physiology · doi:10.1104/pp.110.166652 · Cited by 494
The algal chloroplast as a synthetic biology platform for production of therapeutic proteins
Dyo, Y. M., & Purton, S. (2018) · Microbiology · doi:10.1099/mic.0.000599 · Cited by 140
Rasala, B. A., & Mayfield, S. P. (2011) · Bioengineered Bugs · doi:10.4161/bbug.2.1.13423 · Cited by 122
Metadata
- Authors
- Maul, J. E., Lilly, J. W., Cui, L., dePamphilis, C. W., Miller, W., Harris, E. H., & Stern, D. B.
- Venue
- The Plant Cell
- Publisher
- Oxford University Press (OUP)
- Published
- 2002-11-01
- Volume
- 14
- Issue
- 11
- Pages
- 2659-2679
- ISSN
- 1040-4651 (ISSN-L)
- 1532-298X
- OpenAlex
- W2149213980
- Cited by
- 426
- References
- 2
- FWCI
- 6.91
- Type
- journal article
- Language
- en
- Open access
- green
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: The Chlamydomonas reinhardtii Plastid Chromosome. https://app.cochat.ai/papers/10.1105/tpc.006155
- The paper
- Maul, J. E., Lilly, J. W., Cui, L., dePamphilis, C. W., Miller, W., Harris, E. H., & Stern, D. B. (2002). The Chlamydomonas reinhardtii Plastid Chromosome. The Plant Cell. https://doi.org/10.1105/tpc.006155
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
