The DOI matches its Crossref record; 30 of the 30 references it cites were found in a registry or an index.
AUX/IAA Proteins Are Active Repressors, and Their Stability and Activity Are Modulated by Auxin
Open accessAbstract
Aux/IAA genes are early auxin response genes that encode short-lived nuclear proteins with four conserved domains, referred to as I, II, III, and IV. Arabidopsis Aux/IAA proteins repressed transcription on auxin-responsive reporter genes in protoplast transfection assays. Mutations in domain II resulted in increased repression, whereas mutations in domains I and III partially relieved repression. Aux/IAA proteins fused to a heterologous DNA binding domain were targeted to promoters of constitutively expressed reporter genes and actively repressed transcription in an auxin-responsive and dose-dependent manner. In comparison with an unfused luciferase protein, luciferase fused to Aux/IAA proteins displayed less luciferase activity, which further decreased in the presence of auxin in transfected protoplasts. Domain II mutations increased and domain I mutations decreased luciferase activity with the fusion proteins. These results suggested that Aux/IAA proteins function as active repressors by dimerizing with auxin response factors bound to auxin response elements and that early auxin response genes are regulated by auxin-modulated stabilities of Aux/IAA proteins.
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Cites
Functional analysis of oxidative stress-activated mitogen-activated protein kinase cascade in plants
Kovtun, Y., Chiu, W.-L., Tena, G., & Sheen, J. (2000) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.97.6.2940 · Cited by 1,530
Auxin-responsive gene expression: genes, promoters and regulatory factors
Hagen, G., & Guilfoyle, T. (2002) · Plant Molecular Biology · doi:10.1023/a:1015207114117 · Cited by 1,262
Self-citationARF1, a Transcription Factor That Binds to Auxin Response Elements
Ulmasov, T., Hagen, G., & Guilfoyle, T. J. (1997) · Science · doi:10.1126/science.276.5320.1865 · Cited by 973
Self-citationActivation and repression of transcription by auxin-response factors
Ulmasov, T., Hagen, G., & Guilfoyle, T. J. (1999) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.96.10.5844 · Cited by 805
Self-citationAbel, S., & Theologis, A. (1996) · Plant Physiology · doi:10.1104/pp.111.1.9 · Cited by 762
Ulmasov, T., Murfett, J., Hagen, G., & Guilfoyle, T. J. (1997) · The Plant Cell · doi:10.2307/3870557 · Cited by 679
Self-citationGenetics of Aux/IAA and ARF action in plant growth and development
Liscum, E., & Reed, J. W. (2002) · Auxin Molecular Biology · doi:10.1007/978-94-010-0377-3_10 · Cited by 597
Dimerization and DNA binding of auxin response factors
Ulmasov, T., Hagen, G., & Guilfoyle, T. J. (1999) · The Plant Journal · doi:10.1046/j.1365-313x.1999.00538.x · Cited by 589
Self-citationProtein–protein interactions among the Aux/IAA proteins
Kim, J., Harter, K., & Theologis, A. (1997) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.94.22.11786 · Cited by 542
Control of auxin-regulated root development by the Arabidopsis thaliana SHY2/IAA3 gene
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Cited by
The F-box protein TIR1 is an auxin receptor
Dharmasiri, N., Dharmasiri, S., & Estelle, M. (2005) · Nature · doi:10.1038/nature03543 · Cited by 2,083
Mechanism of auxin perception by the TIR1 ubiquitin ligase
Tan, X., Calderon-Villalobos, L. I. A., Sharon, M., Zheng, C., Robinson, C. V., Estelle, M., & Zheng, N. (2007) · Nature · doi:10.1038/nature05731 · Cited by 1,688
Plant Development Is Regulated by a Family of Auxin Receptor F Box Proteins
Dharmasiri, N., Dharmasiri, S., Weijers, D., Lechner, E., Yamada, M., Hobbie, L., Ehrismann, J. S., Jürgens, G., & Estelle, M. (2005) · Developmental Cell · doi:10.1016/j.devcel.2005.05.014 · Cited by 997
Auxin Receptors and Plant Development: A New Signaling Paradigm
Mockaitis, K., & Estelle, M. (2008) · Annual Review of Cell and Developmental Biology · doi:10.1146/annurev.cellbio.23.090506.123214 · Cited by 651
SCFTIR1/AFB-Based Auxin Perception: Mechanism and Role in Plant Growth and Development
Salehin, M., Bagchi, R., & Estelle, M. (2015) · The Plant Cell · doi:10.1105/tpc.114.133744 · Cited by 462
Metadata
- Authors
- Tiwari, S. B., Wang, X.-J., Hagen, G., & Guilfoyle, T. J.
- Venue
- The Plant Cell
- Publisher
- Oxford University Press (OUP)
- Published
- 2001-12
- Volume
- 13
- Issue
- 12
- Pages
- 2809-2822
- ISSN
- 1040-4651 (ISSN-L)
- 1532-298X
- OpenAlex
- W2161063064
- Cited by
- 555
- References
- 30
- FWCI
- 23.40
- Type
- journal article
- Language
- en
- Open access
- green
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- Tiwari, S. B., Wang, X.-J., Hagen, G., & Guilfoyle, T. J. (2001). AUX/IAA Proteins Are Active Repressors, and Their Stability and Activity Are Modulated by Auxin. The Plant Cell. https://doi.org/10.1105/tpc.010289
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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