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EDS5, an Essential Component of Salicylic Acid–Dependent Signaling for Disease Resistance in Arabidopsis, Is a Member of the MATE Transporter Family
Open accessAbstract
The eds5 mutant of Arabidopsis (earlier named sid1) was shown previously to accumulate very little salicylic acid and PR-1 transcript after pathogen inoculation and to be hypersusceptible to pathogens. We have isolated EDS5 by positional cloning and show that it encodes a protein with a predicted series of nine to 11 membrane-spanning domains and a coil domain at the N terminus. EDS5 is homologous with members of the MATE (multidrug and toxin extrusion) transporter family. EDS5 expression is very low in unstressed plants and strongly induced by pathogens and UV-C light. The transcript starts to accumulate 2 hr after inoculation of Arabidopsis with an avirulent strain of Pseudomonas syringae or UV-C light exposure, and it stays induced for approximately 2 days. EDS5 also is expressed after treatments with salicylic acid, indicating a possible positive feedback regulation. EDS5 expression after infection by certain pathogens as well as after UV-C light exposure depends on the pathogen response proteins EDS1, PAD4, and NDR1, indicating that the signal transduction pathways after UV-C light exposure and pathogen inoculation share common elements.
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Citations
Cited by
Durrant, W. E., & Dong, X. (2004) · Annual Review of Phytopathology · doi:10.1146/annurev.phyto.42.040803.140421 · Cited by 3,184
Salicylic acid, a multifaceted hormone to combat disease
Vlot, A. C., Dempsey, D. A., & Klessig, D. F. (2009) · Annual Review of Phytopathology · doi:10.1146/annurev.phyto.050908.135202 · Cited by 2,568
Systemic Acquired Resistance: Turning Local Infection into Global Defense
Fu, Z. Q., & Dong, X. (2013) · Annual Review of Plant Biology · doi:10.1146/annurev-arplant-042811-105606 · Cited by 1,524
Cross talk between signaling pathways in pathogen defense
Kunkel, B. N., & Brooks, D. M. (2002) · Current Opinion in Plant Biology · doi:10.1016/s1369-5266(02)00275-3 · Cited by 1,451
A High-Throughput Arabidopsis Reverse Genetics System
Sessions, A., Burke, E., Presting, G., Aux, G., McElver, J., Patton, D., Dietrich, B., Ho, P., Bacwaden, J., Ko, C., et al. (2002) · The Plant Cell · doi:10.1105/tpc.004630 · Cited by 961
Metadata
- Authors
- Nawrath, C., Heck, S., Parinthawong, N., & Métraux, J.-P.
- Venue
- The Plant Cell
- Publisher
- Oxford University Press (OUP)
- Published
- 2002-01
- Volume
- 14
- Issue
- 1
- Pages
- 275-286
- ISSN
- 1040-4651 (ISSN-L)
- 1532-298X
- OpenAlex
- W2161459691
- Cited by
- 604
- References
- 0
- FWCI
- 29.85
- Type
- journal article
- Language
- en
- Open access
- bronze
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- Nawrath, C., Heck, S., Parinthawong, N., & Métraux, J.-P. (2002). EDS5, an Essential Component of Salicylic Acid–Dependent Signaling for Disease Resistance in Arabidopsis, Is a Member of the MATE Transporter Family. The Plant Cell. https://doi.org/10.1105/tpc.010376
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