The DOI matches its Crossref record; 61 of the 61 references it cites were found in a registry or an index.
SIZ1-Mediated Sumoylation of ICE1 Controls CBF3/DREB1A Expression and Freezing Tolerance in Arabidopsis
Open accessAbstract
SIZ1 is a SUMO E3 ligase that facilitates conjugation of SUMO to protein substrates. siz1-2 and siz1-3 T-DNA insertion alleles that caused freezing and chilling sensitivities were complemented genetically by expressing SIZ1, indicating that the SIZ1 is a controller of low temperature adaptation in plants. Cold-induced expression of CBF/DREB1, particularly of CBF3/DREB1A, and of the regulon genes was repressed by siz1. siz1 did not affect expression of ICE1, which encodes a MYC transcription factor that is a controller of CBF3/DREB1A. A K393R substitution in ICE1 [ICE1(K393R)] blocked SIZ1-mediated sumoylation in vitro and in protoplasts identifying the K393 residue as the principal site of SUMO conjugation. SIZ1-dependent sumoylation of ICE1 in protoplasts was moderately induced by cold. Sumoylation of recombinant ICE1 reduced polyubiquitination of the protein in vitro. ICE1(K393R) expression in wild-type plants repressed cold-induced CBF3/DREB1A expression and increased freezing sensitivity. Furthermore, expression of ICE1(K393R) induced transcript accumulation of MYB15, which encodes a MYB transcription factor that is a negative regulator of CBF/DREB1. SIZ1-dependent sumoylation of ICE1 may activate and/or stabilize the protein, facilitating expression of CBF3/DREB1A and repression of MYB15, leading to low temperature tolerance.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
PLANT COLD ACCLIMATION: Freezing Tolerance Genes and Regulatory Mechanisms
Thomashow, M. F. (1999) · Annual Review of Plant Physiology and Plant Molecular Biology · doi:10.1146/annurev.arplant.50.1.571 · Cited by 3,551
Liu, Q., Kasuga, M., Sakuma, Y., Abe, H., Miura, S., Yamaguchi-Shinozaki, K., & Shinozaki, K. (1998) · The Plant Cell · doi:10.1105/tpc.10.8.1391 · Cited by 3,044
Yamaguchi-Shinozaki, K., & Shinozaki, K. (2006) · Annual Review of Plant Biology · doi:10.1146/annurev.arplant.57.032905.105444 · Cited by 2,950
Cold, salinity and drought stresses: An overview
Mahajan, S., & Tuteja, N. (2005) · Archives of Biochemistry and Biophysics · doi:10.1016/j.abb.2005.10.018 · Cited by 2,925
Yamaguchi-Shinozaki, K., & Shinozaki, K. (1994) · The Plant Cell · doi:10.1105/tpc.6.2.251 · Cited by 1,993
Regulatory network of gene expression in the drought and cold stress responses
Shinozaki, K., Yamaguchi-Shinozaki, K., & Seki, M. (2003) · Current Opinion in Plant Biology · doi:10.1016/s1369-5266(03)00092-x · Cited by 1,787
Arabidopsis CBF1 Overexpression Induces COR Genes and Enhances Freezing Tolerance
Jaglo-Ottosen, K. R., Gilmour, S. J., Zarka, D. G., Schabenberger, O., & Thomashow, M. F. (1998) · Science · doi:10.1126/science.280.5360.104 · Cited by 1,702
Johnson, E. S. (2004) · Annual Review of Biochemistry · doi:10.1146/annurev.biochem.73.011303.074118 · Cited by 1,675
ICE1: a regulator of cold-induced transcriptome and freezing tolerance in Arabidopsis
Chinnusamy, V., Ohta, M., Kanrar, S., Lee, B.-H., Hong, X., Agarwal, M., & Zhu, J.-K. (2003) · Genes & Development · doi:10.1101/gad.1077503 · Cited by 1,673
Hay, R. T. (2005) · Molecular Cell · doi:10.1016/j.molcel.2005.03.012 · Cited by 1,622
Cited by
AP2/ERF family transcription factors in plant abiotic stress responses
Mizoi, J., Shinozaki, K., & Yamaguchi-Shinozaki, K. (2012) · Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms · doi:10.1016/j.bbagrm.2011.08.004 · Cited by 1,448
Role of DREBs in regulation of abiotic stress responses in plants
Lata, C., & Prasad, M. (2011) · Journal of Experimental Botany · doi:10.1093/jxb/err210 · Cited by 1,016
Molecular Regulation of Plant Responses to Environmental Temperatures
Ding, Y., Shi, Y., & Yang, S. (2020) · Molecular Plant · doi:10.1016/j.molp.2020.02.004 · Cited by 787
Shi, Y., Tian, S., Hou, L., Huang, X., Zhang, X., Guo, H., & Yang, S. (2012) · The Plant Cell · doi:10.1105/tpc.112.098640 · Cited by 709
OST1 Kinase Modulates Freezing Tolerance by Enhancing ICE1 Stability in Arabidopsis
Ding, Y., Li, H., Zhang, X., Xie, Q., Gong, Z., & Yang, S. (2015) · Developmental Cell · doi:10.1016/j.devcel.2014.12.023 · Cited by 676
Metadata
- Authors
- Miura, K., Jin, J. B., Lee, J., Yoo, C. Y., Stirm, V., Miura, T., Ashworth, E. N., Bressan, R. A., Yun, D.-J., & Hasegawa, P. M.
- Venue
- The Plant Cell
- Publisher
- Oxford University Press (OUP)
- Published
- 2007-04-01
- Volume
- 19
- Issue
- 4
- Pages
- 1403-1414
- ISSN
- 1040-4651 (ISSN-L)
- 1532-298X
- OpenAlex
- W1983870100
- Cited by
- 770
- References
- 61
- FWCI
- 38.12
- Type
- journal article
- Language
- en
- Open access
- hybrid
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: SIZ1-Mediated Sumoylation of ICE1 Controls CBF3/DREB1A Expression and Freezing Tolerance in Arabidopsis. https://app.cochat.ai/papers/10.1105/tpc.106.048397
- The paper
- Miura, K., Jin, J. B., Lee, J., Yoo, C. Y., Stirm, V., Miura, T., Ashworth, E. N., Bressan, R. A., Yun, D.-J., & Hasegawa, P. M. (2007). SIZ1-Mediated Sumoylation of ICE1 Controls CBF3/DREB1A Expression and Freezing Tolerance in Arabidopsis. The Plant Cell. https://doi.org/10.1105/tpc.106.048397
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
