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Cited by 362

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Simultaneous maximum a posteriori reconstruction of attenuation and activity distributions from emission sinograms

Nuyts, J., Dupont, P., Stroobants, S., Benninck, R., Mortelmans, L., Suetens, P.·1999·IEEE Transactions on Medical Imaging

Abstract

In order to perform attenuation correction in emission tomography an attenuation map is required. We propose a new method to compute this map directly from the emission sinogram, eliminating the transmission scan from the acquisition protocol. The problem is formulated as an optimization task where the objective function is a combination of the likelihood and an a priori probability. The latter uses a Gibbs prior distribution to encourage local smoothness and a multimodal distribution for the attenuation coefficients. Since the attenuation process is different in positron emission tomography (PET) and single photon emission tomography (SPECT), a separate algorithm for each case is derived. The method has been tested on mathematical phantoms and on a few clinical studies. For PET, good agreement was found between the images obtained with transmission measurements and those produced by the new algorithm in an abdominal study. For SPECT, promising simulation results have been obtained for nonhomogeneous attenuation due to the presence of the lungs.

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Metadata

Authors
Nuyts, J., Dupont, P., Stroobants, S., Benninck, R., Mortelmans, L., & Suetens, P.
Venue
IEEE Transactions on Medical Imaging
Published
1999-05
Volume
18
Issue
5
Pages
393-403
ISSN
0278-0062 (ISSN-L)
OpenAlex
W2145537745
Cited by
362
References
1
FWCI
6.69
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Simultaneous maximum a posteriori reconstruction of attenuation and activity distributions from emission sinograms. https://app.cochat.ai/papers/10.1109/42.774167
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Nuyts, J., Dupont, P., Stroobants, S., Benninck, R., Mortelmans, L., & Suetens, P. (1999). Simultaneous maximum a posteriori reconstruction of attenuation and activity distributions from emission sinograms. IEEE Transactions on Medical Imaging. https://doi.org/10.1109/42.774167

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