The DOI matches its Crossref record; 21 of the 21 references it cites were found in a registry or an index.
Simultaneous Reconstruction of Activity and Attenuation in Time-of-Flight PET
Abstract
In positron emission tomography (PET) and single photon emission tomography (SPECT), attenuation correction is necessary for quantitative reconstruction of the tracer distribution. Previously, several attempts have been made to estimate the attenuation coefficients from emission data only. These attempts had limited success, because the problem does not have a unique solution, and severe and persistent "cross-talk" between the estimated activity and attenuation distributions was observed. In this paper, we show that the availability of time-of-flight (TOF) information eliminates the cross-talk problem by destroying symmetries in the associated Fisher information matrix. We propose a maximum-a-posteriori reconstruction algorithm for jointly estimating the attenuation and activity distributions from TOF PET data. The performance of the algorithm is studied with 2-D simulations, and further illustrated with phantom experiments and with a patient scan. The estimated attenuation image is robust to noise, and does not suffer from the cross-talk that was observed in non-TOF PET. However, some constraining is still mandatory, because the TOF data determine the attenuation sinogram only up to a constant offset.
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Cites
Maximum Likelihood Reconstruction for Emission Tomography
Shepp, L. A., & Vardi, Y. (1982) · IEEE Transactions on Medical Imaging · doi:10.1109/tmi.1982.4307558 · Cited by 4,429
Attenuation correction for a combined 3D PET/CT scanner
Kinahan, P. E., Townsend, D. W., Beyer, T., & Sashin, D. (1998) · Medical Physics · doi:10.1118/1.598392 · Cited by 946
Fessler, J. A., & Rogers, W. L. (1996) · IEEE Transactions on Image Processing · doi:10.1109/83.535846 · Cited by 518
Physical and clinical performance of the mCT time-of-flight PET/CT scanner
Jakoby, B. W., Bercier, Y., Conti, M., Casey, M. E., Bendriem, B., & Townsend, D. W. (2011) · Physics in Medicine and Biology · doi:10.1088/0031-9155/56/8/004 · Cited by 492
Self-citationNuyts, J., Dupont, P., Stroobants, S., Benninck, R., Mortelmans, L., & Suetens, P. (1999) · IEEE Transactions on Medical Imaging · doi:10.1109/42.774167 · Cited by 362
Self-citationTime of flight in PET revisited
Moses, W. W. (2003) · IEEE Transactions on Nuclear Science · doi:10.1109/tns.2003.817319 · Cited by 336
Iterative reconstruction for helical CT: a simulation study
Nuyts, J., Man, B. D., Dupont, P., Defrise, M., Suetens, P., & Mortelmans, L. (1998) · Physics in Medicine and Biology · doi:10.1088/0031-9155/43/4/003 · Cited by 291
Self-citationQuantitative Analysis in Nuclear Medicine Imaging
(2006) · Springer eBooks · doi:10.1007/b107410 · Cited by 266
Time-of-flight PET data determine the attenuation sinogram up to a constant
Defrise, M., Rezaei, A., & Nuyts, J. (2012) · Physics in Medicine and Biology · doi:10.1088/0031-9155/57/4/885 · Cited by 234
Self-citationGrouped-coordinate ascent algorithms for penalized-likelihood transmission image reconstruction
Fessler, J. A., Ficaro, E. P., Clinthorne, N. H., & Lange, K. (1997) · IEEE Transactions on Medical Imaging · doi:10.1109/42.563662 · Cited by 222
Cited by
Attenuation Correction Synthesis for Hybrid PET-MR Scanners: Application to Brain Studies
Burgos, N., Cardoso, M. J., Thielemans, K., Modat, M., Pedemonte, S., Dickson, J., Barnes, A., Ahmed, R., Mahoney, C. J., Schott, J. M., et al. (2014) · IEEE Transactions on Medical Imaging · doi:10.1109/tmi.2014.2340135 · Cited by 364
Roadmap toward the 10 ps time-of-flight PET challenge
Lecoq, P., Morel, C., Prior, J. O., Visvikis, D., Gundacker, S., Auffray, E., Križan, P., Turtos, R. M., Thers, D., Charbon, E., et al. (2020) · Physics in Medicine & Biology · doi:10.1088/1361-6560/ab9500 · Cited by 258
Self-citationMehranian, A., Arabi, H., & Zaidi, H. (2016) · Medical Physics · doi:10.1118/1.4941014 · Cited by 152
Metadata
- Authors
- Rezaei, A., Defrise, M., Bal, G., Michel, C., Conti, M., Watson, C., & Nuyts, J.
- Venue
- IEEE Transactions on Medical Imaging
- Published
- 2012-12
- Volume
- 31
- Issue
- 12
- Pages
- 2224-2233
- ISSN
- 0278-0062 (ISSN-L)
- 1558-254X
- OpenAlex
- W2077939678
- Cited by
- 261
- References
- 21
- FWCI
- 13.80
- Type
- journal article
- Language
- en
- Open access
- closed
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- Rezaei, A., Defrise, M., Bal, G., Michel, C., Conti, M., Watson, C., & Nuyts, J. (2012). Simultaneous Reconstruction of Activity and Attenuation in Time-of-Flight PET. IEEE Transactions on Medical Imaging. https://doi.org/10.1109/tmi.2012.2212719
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