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Nuclei Segmentation with Recurrent Residual Convolutional Neural Networks based U-Net (R2U-Net)

Alom, Md Zahangir, Yakopcic, Chris, Taha, Tarek M., Asari, Vijayan K.·2018·NAECON 2018 - IEEE National Aerospace and Electronics Conference

Abstract

Bio-medical image segmentation is one of the promising sectors where nuclei segmentation from high-resolution histopathological images enables extraction of very high-quality features for nuclear morphometrics and other analysis metrics in the field of digital pathology. The traditional methods including Otsu thresholding and watershed methods do not work properly in different challenging cases. However, Deep Learning (DL) based approaches are showing tremendous success in different modalities of bio-medical imaging including computation pathology. Recently, the Recurrent Residual U-Net (R2U-Net) has been proposed, which has shown state-of-the-art (SOTA) performance in different modalities (retinal blood vessel, skin cancer, and lung segmentation) in medical image segmentation. However, in this implementation, the R2U-Net is applied to nuclei segmentation for the first time on a publicly available dataset that was collected from the Data Science Bowl Grand Challenge in 2018. The R2U-Net shows around 92.15% segmentation accuracy in terms of the Dice Coefficient (DC) during the testing phase. In addition, the qualitative results show accurate segmentation, which clearly demonstrates the robustness of the R2U-Net model for the nuclei segmentation task.

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Metadata

Authors
Alom, M. Z., Yakopcic, C., Taha, T. M., & Asari, V. K.
Venue
NAECON 2018 - IEEE National Aerospace and Electronics Conference
Publisher
IEEE
Published
2018-07
Pages
228-233
OpenAlex
W2905338897
Cited by
1,020
References
18
FWCI
22.57
Type
conference paper
Language
en
Open access
closed

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Alom, M. Z., Yakopcic, C., Taha, T. M., & Asari, V. K. (2018). Nuclei Segmentation with Recurrent Residual Convolutional Neural Networks based U-Net (R2U-Net). NAECON 2018 - IEEE National Aerospace and Electronics Conference. https://doi.org/10.1109/naecon.2018.8556686

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