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Cited by 543

The DOI matches its Crossref record; 90 of the 90 references it cites were found in a registry or an index.

Multisubject Independent Component Analysis of fMRI: A Decade of Intrinsic Networks, Default Mode, and Neurodiagnostic Discovery

Open access
Calhoun, Vince D., Adali, Tülay·2012·IEEE Reviews in Biomedical Engineering

Abstract

Since the discovery of functional connectivity in fMRI data (i.e., temporal correlations between spatially distinct regions of the brain) there has been a considerable amount of work in this field. One important focus has been on the analysis of brain connectivity using the concept of networks instead of regions. Approximately ten years ago, two important research areas grew out of this concept. First, a network proposed to be "a default mode of brain function" since dubbed the default mode network was proposed by Raichle. Secondly, multisubject or group independent component analysis (ICA) provided a data-driven approach to study properties of brain networks, including the default mode network. In this paper, we provide a focused review of how ICA has contributed to the study of intrinsic networks. We discuss some methodological considerations for group ICA and highlight multiple analytic approaches for studying brain networks. We also show examples of some of the differences observed in the default mode and resting networks in the diseased brain. In summary, we are in exciting times and still just beginning to reap the benefits of the richness of functional brain networks as well as available analytic approaches.

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Metadata

Authors
Calhoun, V. D., & Adali, T.
Venue
IEEE Reviews in Biomedical Engineering
Published
2012
Volume
5
Pages
60-73
ISSN
  • 1937-3333 (ISSN-L)
  • 1941-1189
OpenAlex
W1986589478
Cited by
543
References
90
FWCI
14.89
Type
journal article
Language
en
Open access
green

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Calhoun, V. D., & Adali, T. (2012). Multisubject Independent Component Analysis of fMRI: A Decade of Intrinsic Networks, Default Mode, and Neurodiagnostic Discovery. IEEE Reviews in Biomedical Engineering. https://doi.org/10.1109/rbme.2012.2211076

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