A Low-Power Blocking-Capacitor-Free Charge-Balanced Electrode-Stimulator Chip With Less Than 6 nA DC Error for 1-mA Full-Scale Stimulation
Abstract
Large dc blocking capacitors are a bottleneck in reducing the size and cost of neural implants. We describe an electrode-stimulator chip that removes the need for large dc blocking capacitors in neural implants by achieving precise charge-balanced stimulation with <6 nA of dc error. For cochlear implant patients, this is well below the industry's safety limit of 25 nA. Charge balance is achieved by dynamic current balancing to reduce the mismatch between the positive and negative phases of current to 0.4%, followed by a shorting phase of at least 1 ms between current pulses to further reduce the charge error. On +6 and -9 V rails in a 0.7-mum AMI high voltage process, the power consumption of a single channel of this chip is 47 muW when biasing power is shared by 16 channels.
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For cochlear implants the safe limit for injected residual charge has been defined at 15 nC/phase or 100 nA dc error for a 0.01% phase mismatch.
“For cochlear implants this has been defined at 15 nC/phase or 100 nA dc error for a 0.01% phase mismatch [126]”
From Active Neural Interface Circuits and Systems for Selective Control of Peripheral Nerves: A Review (2024) · cites this paper as [126]
Fail-safe blocking capacitor-free stimulator designs have been reported and could be employed instead of blocking capacitors.
“Blocking capacitors are still useful to block direct currents (DCs), but fail-safe blocking capacitor-free stimulator designs have been reported (Liu et al. 2008; Sit and Sarpeshkar 2007), and could be employed instead.”
From Realizing flexible bioelectronic medicines for accessing the peripheral nerves – technology considerations (2018) · cites this paper as Sit and Sarpeshkar 2007
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References 18 · Cited by 155
- Authors
- Sit, J.-J., & Sarpeshkar, R.
- Affiliations
- Advanced Bionics (United States) (US)
- Massachusetts Institute of Technology (US)
- Venue
- IEEE Transactions on Biomedical Circuits and Systems
- Published
- 2007-09
- Volume
- 1
- Issue
- 3
- Pages
- 172-183
- ISSN
- 1932-4545 (ISSN-L)
- 1940-9990
- OpenAlex
- W2165982740
- Cited by
- 155
- References
- 18
- Citations by year
- 2026: 1 · 2025: 5 · 2024: 8 · 2023: 8 · 2022: 6 · 2021: 9 · 2020: 1 · 2019: 9 · 2018: 10 · 2017: 9 · 2016: 15 · 2015: 10 · 2014: 13 · 2013: 13 · 2012: 10
- FWCI
- 4.54
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- IEEE Transactions on Biomedical Circuits and Systems (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Physical Sciences › Engineering › Biomedical Engineering › Analog and Mixed-Signal Circuit Design
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuroscience and Neural Engineering
- Life Sciences › Neuroscience › Cognitive Neuroscience › Hearing Loss and Rehabilitation
- Keywords
- charge balancing, neural implants, cochlear implants, low-power integrated circuits, high-voltage CMOS
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