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Cited by 470

The DOI matches its Crossref record; 46 of the 46 references it cites were found in a registry or an index.

A Comparison of Monodomain and Bidomain Reaction-Diffusion Models for Action Potential Propagation in the Human Heart

Open access
Potse, M., Dube, B., Richer, J., Vinet, A., Gulrajani, R.M.·2006·IEEE Transactions on Biomedical Engineering
DOI 10.1109/tbme.2006.880875
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Abstract

A bidomain reaction-diffusion model of the human heart was developed, and potentials resulting from normal depolarization and repolarization were compared with results from a compatible monodomain model. Comparisons were made for an empty isolated heart and for a heart with fluid-filled ventricles. Both sinus rhythm and ectopic activation were simulated. The bidomain model took 2 days on 32 processors to simulate a complete cardiac cycle. Differences between monodomain and bidomain results were extremely small, even for the extracellular potentials, which in case of the monodomain model were computed with a high-resolution forward model. Propagation of activation was 2% faster in the bidomain model than in the monodomain model. Electrograms computed with monodomain and bidomain models were visually indistinguishable. We conclude that, in the absence of applied currents, propagating action potentials on the scale of a human heart can be studied with a monodomain model.

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Metadata

Authors
Potse, M., Dube, B., Richer, J., Vinet, A., & Gulrajani, R. M.
Venue
IEEE Transactions on Biomedical Engineering
Publisher
Institute of Electrical and Electronics Engineers (IEEE)
Published
2006-12
Volume
53
Issue
12
Pages
2425-2435
ISSN
  • 0018-9294 (ISSN-L)
  • 1558-2531
DOI
10.1109/tbme.2006.880875
OpenAlex
W2098355081
Cited by
470
References
46
FWCI
13.12
Type
journal article
Language
en
Open access
green

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