The DOI matches its Crossref record; 117 of the 117 references it cites were found in a registry or an index.
A Review of Basic to Clinical Studies of Irreversible Electroporation Therapy
Abstract
The use of irreversible electroporation (IRE) for cancer treatment has increased sharply over the past decade. As a nonthermal therapy, IRE offers several potential benefits over other focal therapies, which include 1) short treatment delivery time, 2) reduced collateral thermal injury, and 3) the ability to treat tumors adjacent to major blood vessels. These advantages have stimulated widespread interest in basic through clinical studies of IRE. For instance, many in vitro and in vivo studies now identify treatment planning protocols (IRE threshold, pulse parameters, etc.), electrode delivery (electrode design, placement, intraoperative imaging methods, etc.), injury evaluation (methods and timing), and treatment efficacy in different cancer models. Therefore, this study reviews the in vitro, translational, and clinical studies of IRE cancer therapy based on major experimental studies particularly within the past decade. Further, this study provides organized data and facts to assist further research, optimization, and clinical applications of IRE.
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Self-citationElectroporation of cell membranes
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Electroporation-Based Technologies for Medicine: Principles, Applications, and Challenges
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Intracellular Delivery by Membrane Disruption: Mechanisms, Strategies, and Concepts
Stewart, M. P., Langer, R., & Jensen, K. F. (2018) · Chemical Reviews · doi:10.1021/acs.chemrev.7b00678 · Cited by 747
A Comprehensive Review of Calcium Electroporation—A Novel Cancer Treatment Modality
Frandsen, S. K., Vissing, M., & Gehl, J. (2020) · Cancers · doi:10.3390/cancers12020290 · Cited by 132
López-Alonso, B., Hernáez, A., Sarnago, H., Naval, A., Güemes, A., Junquera, C., Burdío, J. M., Castiella, T., Monleón, E., Gracia-Llanes, J., et al. (2019) · Scientific Reports · doi:10.1038/s41598-019-39433-6 · Cited by 48
Metadata
- Authors
- Jiang, C., Davalos, R. V., & Bischof, J. C.
- Venue
- IEEE Transactions on Biomedical Engineering
- Published
- 2015-01
- Volume
- 62
- Issue
- 1
- Pages
- 4-20
- ISSN
- 0018-9294 (ISSN-L)
- 1558-2531
- OpenAlex
- W2032132376
- Cited by
- 332
- References
- 117
- FWCI
- 27.54
- Type
- journal article
- Language
- en
- Open access
- closed
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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