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Cited by 468

The DOI matches its Crossref record; 20 of the 20 references it cites were found in a registry or an index.

Multiple SVM-RFE for Gene Selection in Cancer Classification With Expression Data

Duan, K.-B., Rajapakse, J.C., Wang, H., Azuaje, F.·2005·IEEE Transactions on Nanobioscience

Abstract

This paper proposes a new feature selection method that uses a backward elimination procedure similar to that implemented in support vector machine recursive feature elimination (SVM-RFE). Unlike the SVM-RFE method, at each step, the proposed approach computes the feature ranking score from a statistical analysis of weight vectors of multiple linear SVMs trained on subsamples of the original training data. We tested the proposed method on four gene expression datasets for cancer classification. The results show that the proposed feature selection method selects better gene subsets than the original SVM-RFE and improves the classification accuracy. A Gene Ontology-based similarity assessment indicates that the selected subsets are functionally diverse, further validating our gene selection method. This investigation also suggests that, for gene expression-based cancer classification, average test error from multiple partitions of training and test sets can be recommended as a reference of performance quality.

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Metadata

Authors
Duan, K.-B., Rajapakse, J. C., Wang, H., & Azuaje, F.
Venue
IEEE Transactions on Nanobioscience
Published
2005-09
Volume
4
Issue
3
Pages
228-234
ISSN
1536-1241 (ISSN-L)
OpenAlex
W2103291381
Cited by
468
References
20
FWCI
3.80
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Multiple SVM-RFE for Gene Selection in Cancer Classification With Expression Data. https://app.cochat.ai/papers/10.1109/tnb.2005.853657
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Duan, K.-B., Rajapakse, J. C., Wang, H., & Azuaje, F. (2005). Multiple SVM-RFE for Gene Selection in Cancer Classification With Expression Data. IEEE Transactions on Nanobioscience. https://doi.org/10.1109/tnb.2005.853657

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