Patterns and predictors of conversion to bipolar disorder in 91 587 individuals diagnosed with unipolar depression.

A Proportional Hazards Model for the Subdistribution of a Competing Risk

Fine, J. P., & Gray, R. J. (1999) · Journal of the American Statistical Association · doi:10.1080/01621459.1999.10474144 · Cited by 14,290 · cited 1× · see citing works

The Danish Civil Registration System

Pedersen, C. (2011) · Scandinavian Journal of Public Health · doi:10.1177/1403494810387965 · Cited by 4,713 · see citing works

The Danish Psychiatric Central Research Register

Mors, O., Perto, G. P., & Mortensen, P. B. (2011) · Scandinavian Journal of Public Health · doi:10.1177/1403494810395825 · Cited by 1,589 · see citing works

A Comprehensive Nationwide Study of the Incidence Rate and Lifetime Risk for Treated Mental Disorders

Pedersen, C. B., Mors, O. N., Bertelsen, A., Waltoft, B. L., Agerbo, E., McGrath, J. J., Mortensen, P. B., & Eaton, W. W. (2014) · JAMA Psychiatry · doi:10.1001/jamapsychiatry.2014.16 · Cited by 623 · see citing works

The World Federation of Societies of Biological Psychiatry (WFSBP) Guidelines for the Biological Treatment of Bipolar Disorders: Update 2012 on the long-term treatment of bipolar disorder

Grunze, H., Vieta, E., Goodwin, G. M., Bowden, C. L., Licht, R. W., Möller, H., Kasper, S. F., & on behalf of the WFSBP Task Force on Treatment Guidelines for Bipolar Disorders (2013) · The World Journal of Biological Psychiatry · doi:10.3109/15622975.2013.770551 · Cited by 421 · see citing works

Historical perspectives and natural history of bipolar disorder

Angst, J., & Sellaro, R. (2000) · Biological Psychiatry · doi:10.1016/s0006-3223(00)00909-4 · Cited by 393 · see citing works

Substance abuse in bipolar disorder

Cassidy, F., Ahearn, E. P., & Carroll, B. J. (2001) · Bipolar Disorders · doi:10.1034/j.1399-5618.2001.30403.x · Cited by 385 · see citing works

Bipolar outcome in the course of depressive illness

Akiskal, H. S., Walker, P. W., Puzantian, V. R., King, D., Rosenthal, T. L., & Dranon, M. (1983) · Journal of Affective Disorders · doi:10.1016/0165-0327(83)90004-6 · Cited by 383 · see citing works

Risk for Bipolar Illness in Patients Initially Hospitalized for Unipolar Depression

Goldberg, J. F., Harrow, M., & Whiteside, J. E. (2001) · American Journal of Psychiatry · doi:10.1176/appi.ajp.158.8.1265 · Cited by 317 · see citing works

Diagnostic conversion from depression to bipolar disorders: results of a long-term prospective study of hospital admissions

Angst, J., Sellaro, R., Stassen, H. H., & Gamma, A. (2003) · Journal of Affective Disorders · doi:10.1016/s0165-0327(03)00195-2 · Cited by 311 · see citing works

Kindling and sensitization as models for affective episode recurrence, cyclicity, and tolerance phenomena

Post, R. M. (2007) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2007.04.003 · Cited by 303 · see citing works

Cannabis use and risk of schizophrenia: a Mendelian randomization study

Vaucher, J., Keating, B. J., Lasserre, A. M., Gan, W., Lyall, D. M., Ward, J., Smıth, D. J., Pell, J. P., Sattar, N. A., Paré, G., et al. (2017) · Molecular Psychiatry · doi:10.1038/mp.2016.252 · Cited by 262 · see citing works

Psychiatric “diseases” versus behavioral disorders and degree of genetic influence

Bienvenu, O., Davydow, D., & Kendler, K. (2010) · Psychological Medicine · doi:10.1017/s003329171000084x · Cited by 244 · see citing works

Duration of untreated illness and suicide in bipolar disorder: a naturalistic study

Altamura, A. C., Dell’Osso, B. M., Berlin, H. A., Buoli, M., Bassetti, R., & Mundo, E. (2009) · European Archives of Psychiatry and Clinical Neuroscience · doi:10.1007/s00406-009-0085-2 · Cited by 212 · see citing works

Assessing causality in associations between cannabis use and schizophrenia risk: a two-sample Mendelian randomization study

Gage, S. H., Jones, H. J., Burgess, S., Bowden, J., Smith, G. D., Zammit, S., & Munafo, M. R. (2016) · Psychological Medicine · doi:10.1017/s0033291716003172 · Cited by 212 · see citing works

At Risk for Schizophrenic or Affective Psychoses? A Meta-Analysis of DSM/ICD Diagnostic Outcomes in Individuals at High Clinical Risk

Fusar‐Poli, P., Bechdolf, A., Taylor, M. J., Bonoldi, I., Carpenter, W. T., Yung, A. R., & McGuire, P. K. (2012) · Schizophrenia Bulletin · doi:10.1093/schbul/sbs060 · Cited by 211 · see citing works

Validity of diagnoses and other clinical register data in patients with affective disorder

Kessing, L. V. (1998) · European Psychiatry · doi:10.1016/s0924-9338(99)80685-3 · Cited by 210 · see citing works

Validity of the diagnosis of a single depressive episode in a case register

Bock, C., Bukh, J. D., Vinberg, M., Gether, U., & Kessing, L. V. (2009) · Clinical Practice and Epidemiology in Mental Health · doi:10.1186/1745-0179-5-4 · Cited by 193 · see citing works

The validity of the schizophrenia diagnosis in the Danish Psychiatric Central Research Register is good.

Uggerby, P., Østergaard, S. D., Røge, R., Correll, C. U., & Nielsen, J. (2013) · PubMed · Cited by 184 · see citing works

Misdiagnosis, duration of untreated illness (DUI) and outcome in bipolar patients with psychotic symptoms: A naturalistic study

Altamura, A. C., Buoli, M., Caldiroli, A., Caron, L., Cumerlato Melter, C., Dobrea, C., Cigliobianco, M., & Zanelli Quarantini, F. (2015) · Journal of Affective Disorders · doi:10.1016/j.jad.2015.04.024 · Cited by 162 · see citing works

A systematic review and meta‐analysis of prospective transition from major depression to bipolar disorder

Ratheesh, A., Davey, C., Hetrick, S., Alvarez‐Jimenez, M., Voutier, C., Bechdolf, A., McGorry, P. D., Scott, J., Berk, M., & Cotton, S. M. (2017) · Acta Psychiatrica Scandinavica · doi:10.1111/acps.12686 · Cited by 142 · see citing works

Register-based studies of mental disorders

Munk‐Jørgensen, P., & Østergaard, S. D. (2011) · Scandinavian Journal of Public Health · doi:10.1177/1403494810390728 · Cited by 132 · see citing works

The predictive validity of bipolar at‐risk (prodromal) criteria in help‐seeking adolescents and young adults: a prospective study

Bechdolf, A., Ratheesh, A., Cotton, S. M., Nelson, B., Chanen, A. M., Betts, J., Bingmann, T., Yung, A. R., Berk, M., & McGorry, P. D. (2014) · Bipolar Disorders · doi:10.1111/bdi.12205 · Cited by 132 · see citing works

First‐episode types in bipolar disorder: predictive associations with later illness

Baldessarini, R. J., Tondo, L., & Visioli, C. (2013) · Acta Psychiatrica Scandinavica · doi:10.1111/acps.12204 · Cited by 122 · see citing works

Early age at onset of bipolar disorder is associated with more severe clinical features but delayed treatment seeking

Suominen, K. H., Mantere, O., Valtonen, H., Arvilommi, P., Leppämäki, S., Paunio, T., & Isometsä, E. T. (2007) · Bipolar Disorders · doi:10.1111/j.1399-5618.2007.00388.x · Cited by 121 · see citing works

Rate and predictors of conversion from unipolar to bipolar disorder: A systematic review and meta‐analysis

Kessing, L. V., Willer, I. S., Andersen, P. K., & Bukh, J. D. (2017) · Bipolar Disorders · doi:10.1111/bdi.12513 · Cited by 94 · see citing works

Relationship of sleep abnormalities to patient genotypes in Prader-Willi syndrome

Vgontzas, A. N., Kales, A., Seip, J. R., Mascari, M. J., Bixler, E. O., Myers, D. C., Vela‐Bueno, A., & Rogan, P. K. (1996) · American Journal of Medical Genetics · doi:10.1002/(sici)1096-8628(19960920)67:5 · Cited by 73 · see citing works

Rates and predictors of remission, recurrence and conversion to bipolar disorder after the first lifetime episode of depression – a prospective 5-year follow-up study

Bukh, J. D., Andersen, P. K., & Kessing, L. V. (2016) · Psychological Medicine · doi:10.1017/s0033291715002676 · Cited by 59 · see citing works

Risk factors for conversion from unipolar psychotic depression to bipolar disorder

Østergaard, S. D., Straszek, S. P. V., Petrides, G., Skadhede, S., Jensen, S. O. W., Munk‐Jørgensen, P., & Nielsen, J. (2013) · Bipolar Disorders · doi:10.1111/bdi.12152 · Cited by 56 · see citing works

Bipolar At-Risk Criteria: An Examination of Which Clinical Features Have Optimal Utility for Identifying Youth at Risk of Early Transition From Depression to Bipolar Disorders

Scott, J. L., Marwaha, S., Ratheesh, A., Macmillan, I., Yung, A. R., Morriss, R. K., Hickie, I. B., & Bechdolf, A. (2016) · Schizophrenia Bulletin · doi:10.1093/schbul/sbw154 · Cited by 54 · see citing works

Psychotic features in bipolar and unipolar depression

Goes, F. S., Sadler, B., Toolan, J., Zamoiski, R. D., Mondimore, F. M., MacKinnon, D. F., Schweizer, B. W., The Bipolar Disorder Phenome Group, DePaulo, J. R., & Potash, J. B. (2007) · Bipolar Disorders · doi:10.1111/j.1399-5618.2007.00460.x · Cited by 53 · see citing works

The association between psychotic mania, psychotic depression and mixed affective episodes among 14,529 patients with bipolar disorder

Østergaard, S. D., Bertelsen, A., Nielsen, J., Mors, O. N., & Petrides, G. (2012) · Journal of Affective Disorders · doi:10.1016/j.jad.2012.10.005 · Cited by 52 · see citing works

Trends in the psychopharmacological treatment of bipolar disorder: a nationwide register-based study

Bjørklund, L. B., Horsdal, H. T., Mors, O. N., Østergaard, S. D., & Gasse, C. (2015) · Acta Neuropsychiatrica · doi:10.1017/neu.2015.52 · Cited by 51 · see citing works

Prospective progression from high-prevalence disorders to bipolar disorder: Exploring characteristics of pre-illness stages

Ratheesh, A., Cotton, S., Betts, J. K., Chanen, A. M., Nelson, B., Davey, C. G., McGorry, P. D., Berk, M., & Bechdolf, A. (2015) · Journal of Affective Disorders · doi:10.1016/j.jad.2015.04.025 · Cited by 45 · see citing works

Environmental and familial risk factors for psychotic and non-psychotic severe depression

Østergaard, S. D., Waltoft, B. L., Mortensen, P. B., & Mors, O. N. (2012) · Journal of Affective Disorders · doi:10.1016/j.jad.2012.11.009 · Cited by 41 · see citing works

Indicators of Mania in Depressed Outpatients

Othmer, E., DeSouza, C., Penick, E. C., Nickel, E. J., Hunter, E. E., Othmer, S. C., Powell, B. J., & Hall, S. (2007) · The Journal of Clinical Psychiatry · doi:10.4088/jcp.v68n0106 · Cited by 36 · see citing works

Conversion from depression to bipolar disorder in a cohort of young people in England, 1999–2011: A national record linkage study

James, A. C., Wotton, C. J., Duffy, A. C., Hoang, U., & Goldacre, M. J. (2015) · Journal of Affective Disorders · doi:10.1016/j.jad.2015.06.018 · Cited by 27 · see citing works

Do patients with bipolar disorder drink alcohol for different reasons when depressed, manic or euthymic?

Meyer, T. D., McDonald, J. L., Douglas, J. L., & Scott, J. L. (2011) · Journal of Affective Disorders · doi:10.1016/j.jad.2011.09.005 · Cited by 26 · see citing works

Delusional depression and bipolar spectrum: evidence for a possible association from a family study of children.

Weissman, M. M., Warner, V., John, K., et al. (1988) · PubMed · Cited by 25 · see citing works

Self‐Report Reasons for Alcohol Use in Bipolar Disorders: Why Drink Despite the Potential Risks?

McDonald, J. L., & Meyer, T. D. (2011) · Clinical Psychology & Psychotherapy · doi:10.1002/cpp.782 · Cited by 22 · see citing works

Progression from unipolar depression to schizophrenia.

Musliner, K. L., Munk‐Olsen, T., Mors, O., & Østergaard, S. D. (2017) · Acta Psychiatrica Scandinavica · doi:10.1111/acps.12663 · Cited by 21 · see citing works

Diagnostic stability in pediatric bipolar disorder

Kessing, L. V., Vradi, E., & Andersen, P. K. (2014) · Journal of Affective Disorders · doi:10.1016/j.jad.2014.10.037 · Cited by 18 · see citing works

Pre-onset risk characteristics for mania among young people at clinical high risk for psychosis

Ratheesh, A., Cotton, S., Davey, C. G., Lin, A. P., Wood, S. J., Yuen, H. P., Bechdolf, A., McGorry, P. D., Yung, A. R., Berk, M., et al. (2017) · Schizophrenia Research · doi:10.1016/j.schres.2017.04.036 · Cited by 6 · see citing works

Bipolar disorder and depression in early adulthood and long-term employment, income, and educational attainment: a nationwide cohort study of 2,390,127 individuals

Hakulinen, C., Musliner, K. L., & Agerbo, E. (2019) · Depression and Anxiety · doi:10.1002/da.22956 · Cited by 108 · see citing works

Association of polygenic liabilities for major depression, bipolar disorder, and schizophrenia with risk for depression in the Danish population

Musliner, K. L., Mortensen, P. B., McGrath, J. J., Suppli, N. P., Hougaard, D. M., Bybjerg-Grauholm, J., Bækvad-Hansen, M., Andreassen, O., Pedersen, C. B., Pedersen, M. G., et al. (2019) · JAMA Psychiatry · doi:10.1001/jamapsychiatry.2018.4166 · Cited by 108 · see citing works

Predicting Diagnostic Progression to Schizophrenia or Bipolar Disorder via Machine Learning

Hansen, L., Bernstorff, M., Enevoldsen, K., Kolding, S., Damgaard, J. G., Perfalk, E., Nielbo, K. L., Danielsen, A. A., & Østergaard, S. D. (2025) · JAMA Psychiatry · doi:10.1001/jamapsychiatry.2024.4702 · Cited by 34 · see citing works

Psychological interventions for young people at risk for bipolar disorder: A systematic review

Perich, T., & Mitchell, P. B. (2019) · Journal of Affective Disorders · doi:10.1016/j.jad.2019.04.058 · Cited by 23 · see citing works

Risk of conversion to bipolar disorder in patients with late-onset major depression

Elefante, C., Brancati, G. E., Petrucci, A., Gemmellaro, T., Toni, C., Lattanzi, L., & Perugi, G. (2022) · International Clinical Psychopharmacology · doi:10.1097/yic.0000000000000421 · Cited by 12 · see citing works

[Concomitant disorders among the mentally retarded].

Haugeberg, G., & Kriz, S. (1990) · PubMed

Concomitant relationship and clinical significance of the arteries and veins of the hand

Li, Z. (2000) · Chinese Journal of Practical Hand Surgery

Concomitant Use of Immunomodulators with Anti-TNF in Crohns Disease: Yes or No?

Meier, J., & Sturm, A. (2010) · Current Drug Targets · doi:10.2174/138945010790309948 · Cited by 10 · see citing works

Patients who are receiving concomitant medications should not systematically be excluded from phase I studies

Genre, D., Viens, P. J., Hoff, D. D. V., et al. (1999) · Anti-Cancer Drugs · doi:10.1097/00001813-199901000-00001 · Cited by 8 · see citing works

R42 The Impact of Concomitant Procedures During Medtronic HVAD Left Ventricular Assist Device Implant

Emmanuel, S., Watson, A., Hayward, C., et al. (2021) · Heart Lung and Circulation · doi:10.1016/j.hlc.2021.03.200