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Long-term survival of pig-to-rhesus macaque renal xenografts is dependent on CD4 T cell depletion

Kim, Steven C., Mathews, David V., Breeden, Cynthia P., Higginbotham, Laura B., Ladowski, Joseph, Martens, Gregory, Stephenson, Allison, Farris, Alton B., Strobert, Elizabeth A., Jenkins, Joe, Walters, Eric M., Larsen, Christian P., Tector, Matthew, Tector, Alfred J., Adams, Andrew B.·2019·American Journal of Transplantation
DOI 10.1111/ajt.15329PMC PMC6658347
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Research works printed but not linked: 63

  1. Giwa, 2017, The promise of organ and tissue preservation to transform medicine, Nat Biotechnol., 35, 530, 10.1038/nbt.3889 · DOI
  2. Wolfe, 2010, Trends in organ donation and transplantation in the United States, 1999-2008, Am J Transplant., 10, 961, 10.1111/j.1600-6143.2010.03021.x · DOI
  3. Chen, 2005, Acute rejection is associated with antibodies to non-Gal antigens in baboons using Gal-knockout pig kidneys, Nat Med., 11, 1295, 10.1038/nm1330 · DOI
  4. Lai, 2002, Production of alpha-1,3-galactosyltransferase knockout pigs by nuclear transfer cloning, Science., 295, 1089, 10.1126/science.1068228 · DOI
  5. Ye, 1994, The pig as a potential organ donor for man. A study of potentially transferable disease from donor pig to recipient man, Transplantation., 57, 694, 10.1097/00007890-199403150-00011 · DOI
  6. Ibrahim, 2006, Selected physiologic compatibilities and incompatibilities between human and porcine organ systems, Xenotransplantation., 13, 488, 10.1111/j.1399-3089.2006.00346.x · DOI
  7. Martin, 2002, Absence of PERV specific humoral immune response in baboons after transplantation of porcine cells or organs, Transpl Int., 15, 361, 10.1111/j.1432-2277.2002.tb00179.x · DOI
  8. Dieckhoff, 2008, Knockdown of porcine endogenous retrovirus (PERV) expression by PERV-specific shRNA in transgenic pigs, Xenotransplantation., 15, 36, 10.1111/j.1399-3089.2008.00442.x · DOI
  9. Cooper, 2014, Progress in pig-to-non-human primate transplantation models (1998-2013): a comprehensive review of the literature, Xenotransplantation., 21, 397, 10.1111/xen.12127 · DOI
  10. Cowan, 2014, Kidney xenotransplantation, Kidney Int., 85, 265, 10.1038/ki.2013.381 · DOI
  11. Pintore, 2013, Clinicopathological findings in non-human primate recipients of porcine renal xenografts: quantitative and qualitative evaluation of proteinuria, Xenotransplantation., 20, 449, 10.1111/xen.12063 · DOI
  12. Shimizu, 2012, Pathologic characteristics of transplanted kidney xenografts, J Am Soc Nephrol., 23, 225, 10.1681/ASN.2011040429 · DOI
  13. Shimizu, 2005, Thrombotic microangiopathic glomerulopathy in human decay accelerating factor-transgenic swine-to-baboon kidney xenografts, J Am Soc Nephrol., 16, 2732, 10.1681/ASN.2004121148 · DOI
  14. Buhler, 2000, Coagulation and thrombotic disorders associated with pig organ and hematopoietic cell transplantation in nonhuman primates, Transplantation., 70, 1323, 10.1097/00007890-200011150-00010 · DOI
  15. Higginbotham, 2015, Pre-transplant antibody screening and anti-CD154 costimulation blockade promote long-term xenograft survival in a pig-to-primate kidney transplant model, Xenotransplantation., 22, 221, 10.1111/xen.12166 · DOI
  16. Iwase, 2017, Immunological and physiological observations in baboons with life-supporting genetically engineered pig kidney grafts, Xenotransplantation., 24, e12293, 10.1111/xen.12293 · DOI · Paper page
  17. Mohiuddin, 2014, One-year heterotopic cardiac xenograft survival in a pig to baboon model, Am J Transplant., 14, 488, 10.1111/ajt.12562 · DOI
  18. McCurry, 1995, Human complement regulatory proteins protect swine-to-primate cardiac xenografts from humoral injury, Nat Med., 1, 423, 10.1038/nm0595-423 · DOI
  19. McCurry, 1995, Transgenic expression of human complement regulatory proteins in mice results in diminished complement deposition during organ xenoperfusion, Transplantation., 59, 1177, 10.1097/00007890-199504000-00017 · DOI
  20. Le Bas-Bernardet, 2011, Xenotransplantation of galactosyl-transferase knockout, CD55, CD59, CD39, and fucosyl-transferase transgenic pig kidneys into baboons, Transpl Proc., 43, 3426, 10.1016/j.transproceed.2011.09.024 · DOI
  21. Cooper, 2017, Joint FDA-IXA symposium, Xenotransplantation., 24, e12365, 10.1111/xen.12365 · DOI
  22. Mohiuddin, 2016, Chimeric 2C10R4 anti-CD40 antibody therapy is critical for long-term survival of GTKO.hCD46.hTBM pig-to-primate cardiac xenograft, Nat Commun., 7, 11138, 10.1038/ncomms11138 · DOI
  23. Iwase, 2015, Pig kidney graft survival in a baboon for 136 days: longest life-supporting organ graft survival to date, Xenotransplantation., 22, 302, 10.1111/xen.12174 · DOI
  24. Thompson, 2011, CD40-specific costimulation blockade enhances neonatal porcine islet survival in nonhuman primates, Am J Transplant., 11, 947, 10.1111/j.1600-6143.2011.03509.x · DOI
  25. Kuwaki, 2004, Suppression of natural and elicited antibodies in pig-to-baboon heart transplantation using a human anti-human CD154 mAb-based regimen, Am J Transplant., 4, 363, 10.1111/j.1600-6143.2004.00353.x · DOI
  26. Samy, 2017, The role of costimulation blockade in solid organ and islet xenotransplantation, J Immunol Res., 2017, 2174, 10.1155/2017/8415205 · DOI
  27. Burlak, 2012, Identification of human preformed antibody targets in GTKO pigs, Xenotransplantation., 19, 92, 10.1111/j.1399-3089.2012.00695.x · DOI
  28. Zhao, 2018, The Sda and Cad glycan antigens and their glycosyltransferase, β1,4GalNAcT-II, in xenotransplantation, Xenotransplantation., 25, e12386, 10.1111/xen.12386 · DOI · Paper page
  29. Ekser, 2009, Xenotransplantation of solid organs in the pig-to-primate model, Transpl Immunol., 21, 87, 10.1016/j.trim.2008.10.005 · DOI
  30. Shearer, 1999, Comparison and characterization of immunoglobulin G subclasses among primate species, Clin Diagn Lab Immunol., 6, 953, 10.1128/CDLI.6.6.953-958.1999 · DOI
  31. Cozzi, 2000, Long-term survival of non-human primates receiving life-supporting transgenic porcine kidney xenografts, Transplantation., 70, 15
  32. Nishimura, 2011, First experience with the use of a recombinant CD3 immunotoxin as induction therapy in pig-to-primate xenotransplantation: the effect of T-cell depletion on outcome, Transplantation., 92, 641, 10.1097/TP.0b013e31822b92a5 · DOI
  33. Griesemer, 2009, Results of gal-knockout porcine thymokidney xenografts, Am J Transplant., 9, 2669, 10.1111/j.1600-6143.2009.02849.x · DOI
  34. Boumpas, 2003, A short course of BG9588 (anti-CD40 ligand antibody) improves serologic activity and decreases hematuria in patients with proliferative lupus glomerulonephritis, Arthritis Rheum., 48, 719, 10.1002/art.10856 · DOI
  35. Huang, 2002, The effect of anti-CD40 ligand antibody on B cells in human systemic lupus erythematosus, Arthritis Rheum., 46, 1554, 10.1002/art.10273 · DOI
  36. Law, 2009, Therapeutic interventions targeting CD40L (CD154) and CD40: the opportunities and challenges, Adv Exp Med Biol., 647, 8, 10.1007/978-0-387-89520-8_2 · DOI
  37. Mohiuddin, 2014, Role of anti-CD40 antibody-mediated costimulation blockade on non-Gal antibody production and heterotopic cardiac xenograft survival in a GTKO.hCD46Tg pig-to-baboon model, Xenotransplantation., 21, 35, 10.1111/xen.12066 · DOI
  38. Goldwater, 2013, A phase 1, randomized ascending single-dose study of antagonist anti-human CD40 ASKP1240 in healthy subjects, Am J Transplant., 13, 1040, 10.1111/ajt.12082 · DOI
  39. Harland, 2015, ASKP1240 in de novo kidney transplant recipients [abstract], Am J Transplant., 15
  40. Okimura, 2014, Characterization of ASKP1240, a fully human antibody targeting human CD40 with potent immunosuppressive effects, Am J Transplant., 14, 1290, 10.1111/ajt.12678 · DOI
  41. Cordoba, 2015, A novel, blocking, Fc-silent anti-CD40 monoclonal antibody prolongs nonhuman primate renal allograft survival in the absence of B cell depletion, Am J Transplant., 15, 2825, 10.1111/ajt.13377 · DOI
  42. Slade, 2015, CFZ533: assessment of immunomodulatory activity following single doses of a novel anti-CD40 mAb in healthy volunteers [abstract], Am J Transpl., 15
  43. Kim, 2017, Fc-silent anti-CD154 domain antibody effectively prevents nonhuman primate renal allograft rejection, Am J Transplant., 17, 1182, 10.1111/ajt.14197 · DOI
  44. Pinelli, 2013, An anti-CD154 domain antibody prolongs graft survival and induces Foxp3+ iTreg in the absence and presence of CTLA-4 Ig, Am J Transplant., 13, 3021, 10.1111/ajt.12417 · DOI
  45. Auchincloss, 1996, Antigen processing and presentation in transplantation, Curr Opin Immunol., 8, 681, 10.1016/S0952-7915(96)80086-0 · DOI
  46. Shoskes, 1994, Indirect presentation of MHC antigens in transplantation, Immunol Today., 15, 32, 10.1016/0167-5699(94)90023-X · DOI
  47. Montecalvo, 2008, Exosomes as a short-range mechanism to spread alloantigen between dendritic cells during T cell allorecognition, J Immunol., 180, 3081, 10.4049/jimmunol.180.5.3081 · DOI
  48. Valujskikh, 2002, Cross-primed CD8(+) T cells mediate graft rejection via a distinct effector pathway, Nat Immunol., 3, 844, 10.1038/ni831 · DOI
  49. Sánchez-Fueyo, 2007, Influence of direct and indirect allorecognition pathways on CD4+CD25+ regulatory T-cell function in transplantation, Transpl Int., 20, 534, 10.1111/j.1432-2277.2007.00470.x · DOI
  50. Sanchez-Fueyo, 2006, Specificity of CD4+CD25+ regulatory T cell function in alloimmunity, J Immunol., 176, 329, 10.4049/jimmunol.176.1.329 · DOI
  51. Kirk, 1993, The human antiporcine cellular response, Transplantation., 55, 924, 10.1097/00007890-199304000-00043 · DOI
  52. Pierson, 1989, Xenogeneic skin graft rejection is especially dependent on CD4+ T cells, J Exp Med., 170, 991, 10.1084/jem.170.3.991 · DOI
  53. Davila, 2006, T-cell responses during pig-to-primate xenotransplantation, Xenotransplantation., 13, 31, 10.1111/j.1399-3089.2005.00258.x · DOI
  54. Markmann, 1994, Genetically engineered grafts to study xenoimmunity: a role for indirect antigen presentation in the destruction of major histocompatibility complex antigen deficient xenografts, Surgery., 116, 242
  55. Heimburg-Molinaro, 2011, Preparation and analysis of glycan microarrays, Curr Protoc Protein Sci., 64, 12, 10.1002/0471140864.ps1210s64 · DOI
  56. Smith, 2010, Use of glycan microarrays to explore specificity of glycan-binding proteins, Methods Enzymol., 480, 417, 10.1016/S0076-6879(10)80033-3 · DOI
  57. Arthur, 2015, Examining galectin binding specificity using glycan microarrays, Methods Mol Biol., 1207, 115, 10.1007/978-1-4939-1396-1_8 · DOI
  58. Estrada, 2015, Evaluation of human and non-human primate antibody binding to pig cells lacking GGTA1/CMAH/β4GalNT2 genes, Xenotransplantation., 22, 194, 10.1111/xen.12161 · DOI · Paper page
  59. Martens, 2017, Humoral reactivity of renal transplant-waitlisted patients to cells from GGTA1/CMAH/β4GalNT2, and SLA class I knockout pigs, Transplantation., 101, 86, 10.1097/TP.0000000000001646 · DOI
  60. Cooper, 2016, Modifying the sugar icing on the transplantation cake, Glycobiology., 26, 571, 10.1093/glycob/cww028 · DOI · Paper page
  61. Wijkstrom, 2017, Renal xenotransplantation: experimental progress and clinical prospects, Kidney Int., 91, 790, 10.1016/j.kint.2016.08.035 · DOI
  62. Cooper, 2017, Regulation of clinical xenotransplantation: time for a reappraisal, Transplantation., 101, 1766, 10.1097/TP.0000000000001683 · DOI
  63. Cooper, 2016, Selection of patients for initial clinical trials of solid organ xenotransplantation, Transplantation., 101, 1551, 10.1097/TP.0000000000001582 · DOI

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Metadata

Authors
Kim, S. C., Mathews, D. V., Breeden, C. P., Higginbotham, L. B., Ladowski, J., Martens, G., Stephenson, A., Farris, A. B., Strobert, E. A., Jenkins, J., Walters, E. M., Larsen, C. P., Tector, M., Tector, A. J., & Adams, A. B.
Venue
American Journal of Transplantation
Publisher
Elsevier BV
Published
2019-08
Volume
19
Issue
8
Pages
2174-2185
ISSN
1600-6135
DOI
10.1111/ajt.15329
PMC
PMC6658347
Cited by
232
References
2
Language
en
Licence
Funders
  • National Institute of Allergy and Infectious Diseases (AI126322)
  • National Institutes of Health (P51OD011132, U42OD011140)

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CoChat. (2026). Citation check: Long-term survival of pig-to-rhesus macaque renal xenografts is dependent on CD4 T cell depletion. https://app.cochat.ai/papers/10.1111/ajt.15329
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Kim, S. C., Mathews, D. V., Breeden, C. P., Higginbotham, L. B., Ladowski, J., Martens, G., Stephenson, A., Farris, A. B., Strobert, E. A., Jenkins, J., Walters, E. M., Larsen, C. P., Tector, M., Tector, A. J., & Adams, A. B. (2019). Long-term survival of pig-to-rhesus macaque renal xenografts is dependent on CD4 T cell depletion. American Journal of Transplantation. https://doi.org/10.1111/ajt.15329