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Evidence for a human-specific mechanism for diet and antibody-mediated inflammation in carcinoma progression

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Potential impact of the non‐human sialic acid <i>N</i>‐glycolylneuraminic acid on transplant rejection risk

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Cloning and expression of porcine β1,4 N‐acetylgalactosaminyl transferase encoding a new xenoreactive antigen

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Novel mechanism for the generation of human xeno-autoantibodies against the nonhuman sialic acid N -glycolylneuraminic acid

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Islet Xenotransplantation Using Gal-Deficient Neonatal Donors Improves Engraftment and Function

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Efficient generation of genetically distinct pigs in a single pregnancy using multiplexed single‐guide RNA and carbohydrate selection

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Human Xeno-Autoantibodies against a Non-Human Sialic Acid Serve as Novel Serum Biomarkers and Immunotherapeutics in Cancer

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Environmental and Molecular Drivers of the α-Gal Syndrome

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Long-Term IgG Response to Porcine Neu5Gc Antigens without Transmission of PERV in Burn Patients Treated with Porcine Skin Xenografts

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Evidence for a novel human-specific xeno-auto-antibody response against vascular endothelium

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First quantification of alpha‐ G al epitope in current glutaraldehyde‐fixed heart valve bioprostheses

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Identification of New Carbohydrate and Membrane Protein Antigens in Cardiac Xenotransplantation

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Skin xenotransplantation: Historical review and clinical potential

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Glycans in immune recognition and response

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Human CD55 Expression Blocks Hyperacute Rejection and Restricts Complement Activation in Gal Knockout Cardiac Xenografts

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Premature Bioprosthetic Aortic Valve Degeneration Associated with Allergy to Galactose‐Alpha‐1,3‐Galactose

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Chronic Survival After Human Renal Homotransplantation Lymphocyte-Antigen Matching, Pathology and Influence of Thymectomy

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Proteomic identification of non‐Gal antibody targets after pig‐to‐primate cardiac xenotransplantation

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A study of the xenoantigenicity of adult pig islets cells

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Human species-specific loss of CMP- <i>N</i> -acetylneuraminic acid hydroxylase enhances atherosclerosis via intrinsic and extrinsic mechanisms

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Reducing immunoreactivity of porcine bioprosthetic heart valves by genetically-deleting three major glycan antigens, GGTA1/β4GalNT2/CMAH

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Parallel evolution of a self-signal: humans and new world monkeys independently lost the cell surface sugar Neu5Gc

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Reduced Binding of Human Antibodies to Cells From GGTA1/CMAH KO Pigs

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α1,3-Galactosyltransferase Gene-Knockout Miniature Swine Produce Natural Cytotoxic Anti-Gal Antibodies

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Potential deleterious role of anti‐Neu5Gc antibodies in xenotransplantation

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Why Is N-Glycolylneuraminic Acid Rare in the Vertebrate Brain?

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Characterization of immunogenic Neu5Gc in bioprosthetic heart valves

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Aiming at the sweet side of cancer: Aberrant glycosylation as possible target for personalized-medicine

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The SdaBlood Group Antigen in Tissues and Body Fluids

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CMP-N-Acetylneuraminic Acid Hydroxylase Is Exclusively Inactive in Humans

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Erythropoietin Produced in a Human Cell Line (Dynepo) Has Significant Differences in Glycosylation Compared with Erythropoietins Produced in CHO Cell Lines

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Host-Derived Sialic Acids Are an Important Nutrient Source Required for Optimal Bacterial Fitness In Vivo

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Cutting Edge: Pig Islet Xenografts Are Susceptible to “Anti-Pig” But Not Galα(1,3)Gal Antibody Plus Complement in Gal o/o Mice

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A Simple Method for Assessment of Human Anti-Neu5Gc Antibodies Applied to Kawasaki Disease

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Early Islet Damage after Direct Exposure of Pig Islets to Blood: Has Humoral Immunity Been Underestimated?

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Erythrocytes from GGTA1/CMAH knockout pigs: implications for xenotransfusion and testing in non‐human primates

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Alpha-Gal Specific IgG Immune Response after Implantation of Bioprostheses

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Inflammatory and immune processes: the neglected villain of bioprosthetic degeneration?

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ANTI-GAL IgG ANTIBODIES IN SERA OF NEWBORN HUMANS AND BABOONS AND ITS SIGNIFICANCE IN PIG XENOTRANSPLANTATION1

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Structural characterization of α1,3-galactosyltransferase knockout pig heart and kidney glycolipids and their reactivity with human and baboon antibodies

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Anti-Neu5Gc and anti-non-Neu5Gc antibodies in healthy humans

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Late onset of development of natural anti-nonGal antibodies in infant humans and baboons: implications for xenotransplantation in infants

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Discovery of the natural anti‐Gal antibody and its past and future relevance to medicine

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Exposure to nonmicrobial N-glycolylneuraminic acid protects farmers' children against airway inflammation and colitis

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Characterization of Natural Human Anti-Non-Gal Antibodies and Their Effect on Activation of Porcine Gal-Deficient Endothelial Cells

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Production of α1,3-galactosyltransferase and cytidine monophosphate-N-acetylneuraminic acid hydroxylase gene double-deficient pigs by CRISPR/Cas9 and handmade cloning

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Tolerization of Galα1,3Gal‐reactive B cells in pre‐sensitized α1,3‐galactosyltransferase‐deficient mice by nonmyeloablative induction of mixed chimerism

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Rabbit antithymocyte globulin–induced serum sickness disease and human kidney graft survival

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Anticarbohydrate Antibody Repertoires in Patients Transplanted with Fetal Pig Islets Revealed by Glycan Arrays

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Biallelic knockout of the α-1,3 galactosyltransferase gene in porcine liver-derived cells using zinc finger nucleases

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Initial in vitro studies on tissues and cells from GTKO/CD46/NeuGcKO pigs

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Generation of α1,3-galactosyltransferase and cytidine monophospho-N-acetylneuraminic acid hydroxylase gene double-knockout pigs

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Deficiency of N-glycolylneuraminic acid and Galα1-3Galβ1-4GlcNAc epitopes in xenogeneic cells attenuates cytotoxicity of human natural antibodies

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α1,3Galactosyltransferase knockout pigs produce the natural anti‐Gal antibody and simulate the evolutionary appearance of this antibody in primates

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Evolution of sialic acids: Implications in xenotransplant biology

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BINDING OF HUMAN NATURAL ANTIBODIES TO NON??Gal XENOANTIGENS ON PORCINE ERYTHROCYTES1

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alpha 1,3-Galactosyltransferase-deficient mice produce naturally occurring cytotoxic anti-Gal antibodies.

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Are humans prone to autoimmunity? Implications from evolutionary changes in hominin sialic acid biology

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Anti‐gal antibodies in α1,3‐galactosyltransferase gene‐knockout pigs

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Generation of cattle knockout for galactose‐α1,3‐galactose and N‐glycolylneuraminic acid antigens

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Immunological Property of Antibodies against N -Glycolylneuraminic Acid Epitopes in Cytidine Monophospho– N -Acetylneuraminic Acid Hydroxylase-Deficient Mice

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Hanganutziu-Deicher antibodies in infectious mononucleosis and other diseases.

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Human antibody recognition of xenogeneic antigens (NeuGc and Gal) on porcine heart valves: could genetically modified pig heart valves reduce structural valve deterioration?

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Antigenicity of tissues and organs from GGTA1/CMAH/β4GalNT2 triple gene knockout pigs

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Loss of CMAH during Human Evolution Primed the Monocyte–Macrophage Lineage toward a More Inflammatory and Phagocytic State

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The Sda and Cad glycan antigens and their glycosyltransferase, β1,4Gal<scp>NA</scp>cT‐<scp>II</scp>, in xenotransplantation

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A study of the xenoantigenicity of neonatal porcine islet‐like cell clusters (NPCC) and the efficiency of adenovirus‐mediated DAF (CD55) expression

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Human antibodies reactive to N eu G c GM 3 ganglioside have cytotoxic antitumor properties

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Distribution of Non-Gal Antigens in Pig Cornea

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Neu5Gc and α1-3 GAL Xenoantigen Knockout Does Not Affect Glycemia Homeostasis and Insulin Secretion in Pigs

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Anti-Gal and Anti-Neu5Gc Responses in Nonimmunosuppressed Patients After Treatment With Rabbit Antithymocyte Polyclonal IgGs

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Impact of European chemicals regulation on the industrial use of plasticizers and patterns of substitution in Scandinavia

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Bortezomib, C1-Inhibitor and Plasma Exchange Do Not Prolong the Survival of Multi-Transgenic GalT-KO Pig Kidney Xenografts in Baboons

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LC–MS Analysis of Polyclonal Human Anti-Neu5Gc Xeno-Autoantibodies Immunoglobulin G Subclass and Partial Sequence Using Multistep Intravenous Immunoglobulin Affinity Purification and Multienzymatic Digestion

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Natural anti-carbohydrate antibodies contributing to evolutionary survival of primates in viral epidemics?

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N-Glycolylneuraminic Acid (Neu5Gc) Null Large Animals by Targeting the CMP-Neu5Gc Hydroxylase (CMAH)

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Release of pig leukocytes during pig kidney perfusion and characterization of pig lymphocyte carbohydrate xenoantigens

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Lack of antibody production against Hanganutziu‐Deicher (H‐D) antigens with N‐glycolylneuraminic acid in patients with porcine exposure history

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α1,3-Galactosyltransferase Deficiency in Germ-Free Miniature Pigs Increases N -Glycolylneuraminic Acids As the Xenoantigenic Determinant in Pig–Human Xenotransplantation

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Complete absence of the αGal xenoantigen and isoglobotrihexosylceramide in α1,3galactosyltransferase knock‐out pigs

Yung, G. P., Li, Y., Borsig, L., Millard, A., Karpova, M. B., Zhou, D., & Seebach, J. D. (2012) · Xenotransplantation · doi:10.1111/j.1399-3089.2012.00705.x · Cited by 29 · see citing works

Silencing the porcine iGb3s gene does not affect Galα3Gal levels or measures of anticipated pig‐to‐human and pig‐to‐primate acute rejection

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Glycan microarray reveal induced IgGs repertoire shift against a dietary carbohydrate in response to rabbit anti-human thymocyte therapy

Amon, R., Ben‐Arye, S. L., Engler, L., Yu, H., Lim, N., Berre, L. L., Harris, K. M., Ehlers, M. R., Gitelman, S. E., Chen, X., et al. (2017) · Oncotarget · doi:10.18632/oncotarget.23096 · Cited by 29 · see citing works

Immunogenicity of Renal Microvascular Endothelial Cells From Genetically Modified Pigs

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Decrease of blood anti-α1,3 Galactose Abs levels in multiple sclerosis (MS) and clinically isolated syndrome (CIS) patients

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Expression of NeuGc on Pig Corneas and Its Potential Significance in Pig Corneal Xenotransplantation

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Poor Patient and Graft Outcome After Induction Treatment by Antithymocyte Globulin in Recipients of a Kidney Graft After Nonrenal Organ Transplantation

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Inclusion of homologous DNA in nuclease‐mediated gene targeting facilitates a higher incidence of bi‐allelically modified cells

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No Increase in Colon Cancer Risk Following Induction with Neu5Gc-Bearing Rabbit Anti-T Cell IgG (ATG) in Recipients of Kidney Transplants

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The Structural Complexity and Animal Tissue Distribution of N-Glycolylneuraminic Acid (Neu5Gc)-Terminated Glycans. Implications for Their Immunogenicity in Clinical Xenografting

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Elicited and pre‐existing anti‐Neu5Gc antibodies differentially affect human endothelial cells transcriptome

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A lectin microarray study of glycoantigens in neonatal porcine islet-like cell clusters

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First quantification of alpha‐Gal epitope in current glutaraldehyde‐fixed heart valve bioprosthesis (by Naso et al.)

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Porcine B4GALNT2 a Source of New Xenogenic Glycan

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Immunogenicity of decellularized extracellular matrix scaffolds: a bottleneck in tissue engineering and regenerative medicine

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Antibody‐mediated rejection in xenotransplantation: Can it be prevented or reversed?

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Anti-glycan antibodies: roles in human disease

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Where’s the Beef? Understanding Allergic Responses to Red Meat in Alpha-Gal Syndrome

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Type 1 diabetes and engineering enhanced islet transplantation

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Next steps for the xenotransplantation of pig organs into humans

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Immunoprotection Strategies in β‐Cell Replacement Therapy: A Closer Look at Porcine Islet Xenotransplantation

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Advancements and Perspectives in the Bioprosthetic Heart Valve: A Comprehensive Review on Biomaterial Processing and Emerging Polymeric Materials

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Effects of human TFPI and CD47 expression and selectin and integrin inhibition during GalTKO.hCD46 pig lung perfusion with human blood

Miura, S., Habibabady, Z. A., Pollok, F., Connolly, M. R., Pratts, S. G., Dandro, A. S., Sorrells, L., Karavi, K., Phelps, C. J., Eyestone, W., et al. (2022) · Xenotransplantation · doi:10.1111/xen.12725 · Cited by 16 · see citing works

Current views on N-glycolylneuraminic acid in therapeutic recombinant proteins

Mastrangeli, R., Audino, M. C., Palinsky, W., Broly, H., & Bierau, H. (2021) · Trends in Pharmacological Sciences · doi:10.1016/j.tips.2021.08.004 · Cited by 14 · see citing works

Recent advances in porcine cardiac xenotransplantation: from aortic valve replacement to heart transplantation

Kavarana, S., Kwon, J. H., Zilinskas, K., Kang, L., Turek, J. W., Mohiuddin, M. M., & Rajab, T. K. (2022) · Expert Review of Cardiovascular Therapy · doi:10.1080/14779072.2022.2100760 · Cited by 13 · see citing works

Genetic knockout of porcine GGTA1 or CMAH/GGTA1 is associated with the emergence of neo‐glycans

Morticelli, L., Rossdam, C., Cajic, S., Böthig, D., Magdei, M., Tuladhar, S. R., Petersen, B., Fischer, K., Rapp, E., Korossis, S., et al. (2023) · Xenotransplantation · doi:10.1111/xen.12804 · Cited by 13 · see citing works

Xenotransplantation

Tatapudi, V., Mattoo, A., Schiff, T., Mehta, S. A., Skolnik, E. Y., & Montgomery, R. A. (2025) · Journal of the American Society of Nephrology · doi:10.1681/asn.0000000745 · Cited by 11 · see citing works

Xenotransplantation of neonatal porcine bone marrow–derived mesenchymal stem cells improves diabetic wound healing by promoting angiogenesis and lymphangiogenesis

Yamada, H., Naito, R., Nishimura, M., Kawakami, R., Morinaga, E., Morita, Y., Shimizu, M., Yoshimatsu, G., Sawamoto, O., Matsumoto, S., et al. (2022) · Xenotransplantation · doi:10.1111/xen.12739 · Cited by 11 · see citing works

GENE-MODIFIED PIGS AS DONORS FOR LIVER XENOTRANSPLANTATION: HOW MANY MODIFICATIONS ARE NEEDED?

Huai, G., Du, J., Zhang, Z., Gonelle‐Gispert, C., Zhang, X., Dou, K., Deng, S., Pan, D., & Bühler, L. H. (2023) · European Journal of Transplantation · doi:10.57603/ejt-271 · Cited by 11 · see citing works

Recent progress in pig-to-human kidney xenotransplantation

Tao, P., & Zhou, K. (2025) · Frontiers in Immunology · doi:10.3389/fimmu.2025.1735113 · Cited by 10 · see citing works

Graft rejection in paediatric congenital heart disease

Harris, A. G., Iacobazzi, D., Caputo, M., & Bartoli‐Leonard, F. (2023) · Translational Pediatrics · doi:10.21037/tp-23-80 · Cited by 9 · see citing works

Immune disguise: the mechanisms of Neu5Gc inducing autoimmune and transplant rejection

Ding, F., Lin, Y.-F., Liu, G., Liu, Y., Gao, F., Liu, Q., Zhang, Z., & Weng, S. (2022) · Genes and Immunity · doi:10.1038/s41435-022-00182-8 · Cited by 9 · see citing works

Experimental Swine Models for Vascularized Composite Allotransplantation and Immunosuppression: A Systematic Review and Case Report of a Novel Heterotopic Hemifacial Swine Model

Knoedler, L., Klimitz, F. J., Huelsboemer, L. F., Niederegger, T., Schaschinger, T., Knoedler, S. A., Boroumand, S., Brown, S., Pomahač, B., & Kauke‐Navarro, M. (2025) · Transplant International · doi:10.3389/ti.2025.14520 · Cited by 8 · see citing works

An Overview of the Importance and Value of Porcine Species in Sialic Acid Research

Ogun, O. J., Thaller, G. E., & Becker, D. (2022) · Biology · doi:10.3390/biology11060903 · Cited by 8 · see citing works

IMMUNOBIOLOGICAL BARRIERS TO PIG ORGAN XENOTRANSPLANTATION

Cooper, D. K. C., Wang, L., Kinoshita, K., Habibabady, Z. A., Rosales, I. A., Kobayashi, T., & Hara, H. (2023) · European Journal of Transplantation · doi:10.57603/ejt-266 · Cited by 8 · see citing works

Engineering Efforts to Refine Compatibility and Duration of Aortic Valve Replacements: An Overview of Previous Expectations and New Promises

Rizzi, S., Ragazzini, S., & Pesce, M. (2022) · Frontiers in Cardiovascular Medicine · doi:10.3389/fcvm.2022.863136 · Cited by 8 · see citing works

Knock‐out of N‐glycolylneuraminic acid attenuates antibody‐mediated rejection in xenogenically perfused porcine lungs

Chaban, R., Habibabady, Z. A., Hassanein, W., Connolly, M. R., Burdorf, L., Redding, E., Laird, C. T., Ranek, J. S., Braileanu, G., Sendil, S., et al. (2022) · Xenotransplantation · doi:10.1111/xen.12784 · Cited by 8 · see citing works

Innovative Metrics for Reporting and Comparing the Glycan Structural Profile in Biotherapeutics

Mastrangeli, R., Satwekar, A., & Bierau, H. (2023) · Molecules · doi:10.3390/molecules28083304 · Cited by 7 · see citing works

Optimal temperature for the long-term culture of adult porcine islets for xenotransplantation

Sakata, N., Yoshimatsu, G., Kawakami, R., Aoyagi, C., & Kodama, S. (2023) · Frontiers in Immunology · doi:10.3389/fimmu.2023.1280668 · Cited by 6 · see citing works

Xenotransplantation: how close are we?

Aschheim, K., & DeFrancesco, L. (2023) · Nature Biotechnology · doi:10.1038/s41587-023-01730-x · Cited by 5 · see citing works

LIS1, a glyco-humanized swine polyclonal anti-lymphocyte globulin, as a novel induction treatment in solid organ transplantation

Rousse, J., Royer, P., Evanno, G., Lhériteau, E., Ciron, C., Salama, A., Shneiker, F., Duchi, R., Perota, A., Galli, C., et al. (2023) · Frontiers in Immunology · doi:10.3389/fimmu.2023.1137629 · Cited by 5 · see citing works

The Effect of Recombinant Human Alpha-1,2-Fucosyltransferase and Alpha-Galactosidase A on the Reduction of Alpha-Gal Expression in the Liver of Transgenic Pigs

Wiater, J., Karasiński, J., Słomski, R., Smorąg, Z., Wartalski, K., Gajda, B., Jura, J., & Romek, M. (2020) · Folia Biologica · doi:10.3409/fb_68-4.14 · Cited by 5 · see citing works

Immune Landscape in Kidney Transplantation

Niu, D., Chen, R., & Pang, X. (2025) · Journal of Inflammation Research · doi:10.2147/jir.s553007 · Cited by 4 · see citing works

Addressing glycan and hematological barriers in pig-to-nonhuman primate liver xenotransplantation: challenges and future directions

Kim, J. Y. (2024) · Clinical Transplantation and Research · doi:10.4285/ctr.24.0044 · Cited by 4 · see citing works

Effect of Factor H on Complement Alternative Pathway Activation in Human Serum Remains on Porcine Cells Lacking N-Glycolylneuraminic Acid

Lee, H., Park, E. M., Ko, N., Choi, K., Oh, K. B., & Kang, H. J. (2022) · Frontiers in Immunology · doi:10.3389/fimmu.2022.859261 · Cited by 3 · see citing works

Transgenic pigs for islet xenotransplantation

Cowan, P. J. (2022) · Elsevier eBooks · doi:10.1016/b978-0-12-824011-3.00006-0 · Cited by 3 · see citing works

Influence of relatively short-term culture on adult porcine islets for xenotransplantation

Sakata, N., Yoshimatsu, G., Kawakami, R., & Kodama, S. (2024) · Scientific Reports · doi:10.1038/s41598-024-62570-6 · Cited by 3 · see citing works

Advancing kidney xenotransplantation with anesthesia and surgery - bridging preclinical and clinical frontiers challenges and prospects

Zhang, X., Wang, H., Xie, Q., Zhang, Y., Yang, Y., Yuan, M., Cui, Y., Song, S., Lv, J., & Wang, Y. (2024) · Frontiers in Immunology · doi:10.3389/fimmu.2024.1386382 · Cited by 2 · see citing works

Proteomic Identification of Pig Xenoantigens for Clinical Xenotransplantation

Liu, H., Hoang, T., Hu, Y., Xu, Y., Sun, Z., Peiffer, B. J., Huang, Y., Sun, Z., & Zhang, H. (2026) · Journal of Proteome Research · doi:10.1021/acs.jproteome.5c01244 · Cited by 2 · see citing works

A Half-Century of Heterotopic Heart Transplantation in Mice: The Spearhead of Immunology Research

Yin, D., Dewald, O., Peng, X., Nie, W., Rong, S., Dudziak, D., Lehmann, C. H. K., Hoerning, A., & Fu, J. (2024) · Transplantology · doi:10.3390/transplantology5040030 · Cited by 1 · see citing works

Early Experimental Report of the First 8‐Gene‐Edited Pig‐to‐Rhesus Macaque Cardiac Xenotransplantation in China

Wang, X., Wu, X., Dai, Z., Yan, L., Yan, J., He, D., Li, S., Ren, Z., Zhang, G., Cui, G., et al. (2026) · Xenotransplantation · doi:10.1111/xen.70137 · Cited by 1 · see citing works

Xenotransplantation literature update, November/December 2020

Hawthorne, W. J., Thomas, A., & Burlak, C. (2021) · Xenotransplantation · doi:10.1111/xen.12674 · Cited by 1 · see citing works

Cell Function Research of β-Trefoil Lectins from Mytilidae

Fujii, Y. (2021) · YAKUGAKU ZASSHI · doi:10.1248/yakushi.20-00215 · Cited by 1 · see citing works

Current Aspects of Xenotransplantation in Human

Kunopasvorakul, P. (2022) · International Journal of Current Science Research and Review · doi:10.47191/ijcsrr/v5-i6-15 · Cited by 1 · see citing works

Serum Anti-Carbohydrate Antibodies and Hyperacute Rejection

Guy, A. J., & Ramsland, P. A. (2020) · Elsevier eBooks · doi:10.1016/b978-0-12-819475-1.00070-5

ANOTHER LOOK AT THE DIMENSIONALITY ON THE INTERNAL-EXTERNAL CONTROL CONSTRUCT.

Sugden, B. W. (1974) · Lincoln (University of Nebraska)

Xenotransplantation: The next quarter century

Tector, A. J., Tector, M., Vianna, R., & Adams, A. B. (2025) · Transplantation Reports · doi:10.1016/j.tpr.2025.100177

Genveränderte Schweinelunge erstmals in Menschen verpflanzt

Gillissen, A. (2025) · Pneumo News · doi:10.1007/s15033-025-4228-6

Generation of Cloned Sheep Lacking Galactose‐α1,3‐Galactose and N‐Glycolylneuraminic Acid Antigens

Appleby, S. J., Fermin, L., McLean, Z. L., Delaney, S., Wagner, S., Genova, C. D., Wei, J., Meng, F., Wells, D. N., & Oback, B. J. (2026) · Xenotransplantation · doi:10.1111/xen.70134

From regenerative medicine to food biofabrication: cultivation of porcine skin for human consumption

Wensing, C. S., Bressan, F. F., Valencia, G. A., Gomes, A. M., & Verruck, S. (2026) · Food Research International · doi:10.1016/j.foodres.2026.118584

Xenotransplantation: Promise, progress, and risks

Zheng, P., & Zheng, S. (2026) · Veterinary Immunology and Immunopathology · doi:10.1016/j.vetimm.2026.111110

Immunosuppressive Strategies in Kidney Xenotransplantation with an Emphasis on Complement Inhibition

Casiraghi, F., Azzollini, N., Remuzzi, G., & Perico, N. (2026) · The Nephron journals/Nephron journals · doi:10.1159/000552496

An Immunological and Translational Framework for Interspecies Exogenic Liver Transplantation

Rao, J. S., Shetty, A. V., Ramachandran, S., Low, W. C., & Steer, C. J. (2026) · Cell Transplantation · doi:10.1177/09636897261479189

Triple gene-knockout xenogeneic bone repair material achieves synergistic optimization of bone repair immunomicroenvironment and bone regeneration via antigen-immunity-inflammation axis modulation

Han, Y., Hu, Y., Lu, Y., Wang, R., Wang, Y., Chen, Z., Yang, Z., Liang, X., Yan, J., & Xie, Y. (2026) · Biomaterials · doi:10.1016/j.biomaterials.2026.124609

Neu5Gc and beyond: sialylation at the innate immune and thromboinflammatory interface of xenotransplantation

Kim, J. Y. (2026) · Frontiers in Transplantation · doi:10.3389/frtra.2026.1968710

Glycosylation in Quality and Safety of Therapeutic Proteins

Matsumoto, Y., Kim, J., McKenna, K. R., Biel, T. G., Kirshner, S., Falkowski, V. M., & Ju, T. (2026) · Pharmacological Reviews · doi:10.1016/j.pharmr.2026.100163

Potential deleterious role of anti‐Neu5Gc antibodies in xenotransplantation

Salama, A., Evanno, G., Harb, J., & Soulillou, J. (2015) · Xenotransplantation · doi:10.1111/xen.12142 · Cited by 81 · see citing works

Potential impact of the non‐human sialic acid <i>N</i>‐glycolylneuraminic acid on transplant rejection risk

Padler‐Karavani, V., & Varki, A. (2011) · Xenotransplantation · doi:10.1111/j.1399-3089.2011.00622.x · Cited by 162 · see citing works

Recent investigations into pig antigen and anti-pig antibody expression

Byrne, G. W., McGregor, C. G. A., & Breimer, M. E. (2015) · International Journal of Surgery · doi:10.1016/j.ijsu.2015.07.724 · Cited by 76 · see citing works

Anti‐N‐glycolylneuraminic acid antibodies identified in healthy human serum

Zhu, A., & Hurst, R. (2002) · Xenotransplantation · doi:10.1034/j.1399-3089.2002.02138.x · Cited by 274 · see citing works

Human antibody reactivity against xenogeneic N‐glycolylneuraminic acid and galactose‐α‐1,3‐galactose antigen

Hurh, S., Kang, B., Choi, I., Cho, B., Lee, E. M., Kim, H., Kim, Y. J., Chung, Y. S., Jeong, J. C., Hwang, J., et al. (2016) · Xenotransplantation · doi:10.1111/xen.12239 · Cited by 31 · see citing works