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Cited by 802

The DOI matches its Crossref record; 7 of the 7 references it cites were found in a registry or an index.

COVID-19 in solid organ transplant recipients: Initial report from the US epicenter

Open access
Pereira, Marcus R., Mohan, Sumit, Cohen, David J., Husain, Syed A., Dube, Geoffrey K., Ratner, Lloyd E., Arcasoy, Selim, Aversa, Meghan M., Benvenuto, Luke J., Dadhania, Darshana M., Kapur, Sandip, Dove, Lorna M., Brown, Robert S., Rosenblatt, Russell E., Samstein, Benjamin, Uriel, Nir, Farr, Maryjane A., Satlin, Michael, Small, Catherine B., Walsh, Thomas J., Kodiyanplakkal, Rosy P., Miko, Benjamin A., Aaron, Justin G., Tsapepas, Demetra S., Emond, Jean C., Verna, Elizabeth C.·2020·American Journal of Transplantation

Abstract

Solid organ transplant recipients may be at a high risk for SARS-CoV-2 infection and poor associated outcomes. We herein report our initial experience with solid organ transplant recipients with SARS-CoV-2 infection at two centers during the first 3 weeks of the outbreak in New York City. Baseline characteristics, clinical presentation, antiviral and immunosuppressive management were compared between patients with mild/moderate and severe disease (defined as ICU admission, intubation or death). Ninety patients were analyzed with a median age of 57 years. Forty-six were kidney recipients, 17 lung, 13 liver, 9 heart, and 5 dual-organ transplants. The most common presenting symptoms were fever (70%), cough (59%), and dyspnea (43%). Twenty-two (24%) had mild, 41 (46%) moderate, and 27 (30%) severe disease. Among the 68 hospitalized patients, 12% required non-rebreather and 35% required intubation. 91% received hydroxychloroquine, 66% azithromycin, 3% remdesivir, 21% tocilizumab, and 24% bolus steroids. Sixteen patients died (18% overall, 24% of hospitalized, 52% of ICU) and 37 (54%) were discharged. In this initial cohort, transplant recipients with COVID-19 appear to have more severe outcomes, although testing limitations likely led to undercounting of mild/asymptomatic cases. As this outbreak unfolds, COVID-19 has the potential to severely impact solid organ transplant recipients.

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Metadata

Authors
Pereira, M. R., Mohan, S., Cohen, D. J., Husain, S. A., Dube, G. K., Ratner, L. E., Arcasoy, S., Aversa, M. M., Benvenuto, L. J., Dadhania, D. M., Kapur, S., Dove, L. M., Brown, R. S., Rosenblatt, R. E., Samstein, B., Uriel, N., Farr, M. A., Satlin, M., Small, C. B., Walsh, T. J., Kodiyanplakkal, R. P., Miko, B. A., Aaron, J. G., Tsapepas, D. S., Emond, J. C., & Verna, E. C.
Venue
American Journal of Transplantation
Publisher
Elsevier BV
Published
2020-07
Volume
20
Issue
7
Pages
1800-1808
ISSN
1600-6135 (ISSN-L)
OpenAlex
W3017734961
Cited by
802
References
7
FWCI
21.88
Type
journal article
Language
en
Open access
hybrid

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CoChat. (2026). Citation check: COVID-19 in solid organ transplant recipients: Initial report from the US epicenter. https://app.cochat.ai/papers/10.1111/ajt.15941
The paper
Pereira, M. R., Mohan, S., Cohen, D. J., Husain, S. A., Dube, G. K., Ratner, L. E., Arcasoy, S., Aversa, M. M., Benvenuto, L. J., Dadhania, D. M., Kapur, S., Dove, L. M., Brown, R. S., Rosenblatt, R. E., Samstein, B., Uriel, N., Farr, M. A., Satlin, M., Small, C. B., . . . Verna, E. C. (2020). COVID-19 in solid organ transplant recipients: Initial report from the US epicenter. American Journal of Transplantation. https://doi.org/10.1111/ajt.15941

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

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