First case of 2019 novel coronavirus in the United States
Open accessAbstract
An outbreak of novel coronavirus (2019-nCoV) that began in Wuhan, China, has spread rapidly, with cases now confirmed in multiple countries. We report the first case of 2019-nCoV infection confirmed in the United States and describe the identification, diagnosis, clinical course, and management of the case, including the patient's initial mild symptoms at presentation with progression to pneumonia on day 9 of illness. This case highlights the importance of close coordination between clinicians and public health authorities at the local, state, and federal levels, as well as the need for rapid dissemination of clinical information related to the care of patients with this emerging infection.
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The first diagnosis of COVID-19 in the United States was on Jan 20, 2020, in a traveller who had returned from Wuhan on Jan 15, 2020.
“The first diagnosis of COVID-19 in the United States was on Jan 20, 2020,102 in a traveller who had returned to the United States from Wuhan on Jan 15, 2020.”
From The Lancet Commission on lessons for the future from the COVID-19 pandemic (2022) · cites this paper as [102]
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- Authors
- Holshue, M. L., DeBolt, C., Lindquist, S., Lofy, K. H., Wiesman, J., Bruce, H., Spitters, C., Ericson, K., Wilkerson, S., Tural, A., Diaz, G., Cohn, A., Fox, L., Patel, A., Gerber, S. I., Kim, L., Tong, S., Lu, X., Lindstrom, S., Pallansch, M. A., Weldon, W. C., Biggs, H. M., Uyeki, T. M., & Pillai, S. K.
- Affiliations
- Centers for Disease Control and Prevention (US)
- Corresponding author
- Holshue, Michelle L.
- ORCID
- Venue
- New England Journal of Medicine
- Publisher
- Massachusetts Medical Society
- Published
- 2020-03-05
- Volume
- 382
- Issue
- 10
- Pages
- 929-936
- ISSN
- 0028-4793 (ISSN-L)
- 1533-4406
- PMC
- PMC7092802
- OpenAlex
- W3003465021
- Cited by
- 6,030
- References
- 8
- Citations by year
- 2026: 40 · 2025: 80 · 2024: 197 · 2023: 375 · 2022: 705 · 2021: 1546 · 2020: 3075 · 2019: 6 · 2018: 1 · 2013: 1
- FWCI
- 187.15
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- New England Journal of Medicine (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Infectious Diseases › COVID-19 Clinical Research Studies
- Health Sciences › Medicine › Infectious Diseases › SARS-CoV-2 and COVID-19 Research
- Health Sciences › Medicine › Infectious Diseases › Viral Infections and Outbreaks Research
- Keywords
- SARS-CoV-2, clinical course, pneumonia, emerging infectious diseases, public health coordination, clinical management
- MeSH terms
- Betacoronavirus, COVID-19, SARS-CoV-2, COVID-19 Testing, Adult, Blood Chemical Analysis, China, Humans, Lung, Male, Pneumonia, Viral, Radiography, Thoracic, Travel, United States, Genome, Viral, Sequence Analysis, DNA, Coronavirus Infections, Disease Progression, Clinical Laboratory Techniques
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