Cited by 6,030COVID-19 Clinical Research StudiesSARS-CoV-2 and COVID-19 ResearchViral Infections and Outbreaks Research

First case of 2019 novel coronavirus in the United States

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Holshue, Michelle L., DeBolt, Chas, Lindquist, Scott, Lofy, Kathy H., Wiesman, John, Bruce, Hollianne, Spitters, Christopher, Ericson, Keith +16 more·2020·New England Journal of Medicine

Abstract

An outbreak of novel coronavirus (2019-nCoV) that began in Wuhan, China, has spread rapidly, with cases now confirmed in multiple countries. We report the first case of 2019-nCoV infection confirmed in the United States and describe the identification, diagnosis, clinical course, and management of the case, including the patient's initial mild symptoms at presentation with progression to pneumonia on day 9 of illness. This case highlights the importance of close coordination between clinicians and public health authorities at the local, state, and federal levels, as well as the need for rapid dissemination of clinical information related to the care of patients with this emerging infection.

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Crossref · 10.1056/nejmoa2001191

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  • The first diagnosis of COVID-19 in the United States was on Jan 20, 2020, in a traveller who had returned from Wuhan on Jan 15, 2020.

    “The first diagnosis of COVID-19 in the United States was on Jan 20, 2020,102 in a traveller who had returned to the United States from Wuhan on Jan 15, 2020.”

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Research works printed but not linked: 1

  1. [16]National Institutes of Health. GenBank overview (https://www.ncbi.nlm.nih.gov/genbank/).

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Authors
Holshue, M. L., DeBolt, C., Lindquist, S., Lofy, K. H., Wiesman, J., Bruce, H., Spitters, C., Ericson, K., Wilkerson, S., Tural, A., Diaz, G., Cohn, A., Fox, L., Patel, A., Gerber, S. I., Kim, L., Tong, S., Lu, X., Lindstrom, S., Pallansch, M. A., Weldon, W. C., Biggs, H. M., Uyeki, T. M., & Pillai, S. K.
Affiliations
Centers for Disease Control and Prevention (US)
Corresponding author
Holshue, Michelle L.
Venue
New England Journal of Medicine
Published
2020-03-05
Volume
382
Issue
10
Pages
929-936
ISSN
  • 0028-4793 (ISSN-L)
  • 1533-4406
OpenAlex
W3003465021
Cited by
6,030
References
8
Citations by year
2026: 40 · 2025: 80 · 2024: 197 · 2023: 375 · 2022: 705 · 2021: 1546 · 2020: 3075 · 2019: 6 · 2018: 1 · 2013: 1
FWCI
187.15
Type
journal article
Language
en
Open access
Locations
  • New England Journal of Medicine (publishedVersion)
  • PubMed Central (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Infectious Diseases › COVID-19 Clinical Research Studies
  • Health Sciences › Medicine › Infectious Diseases › SARS-CoV-2 and COVID-19 Research
  • Health Sciences › Medicine › Infectious Diseases › Viral Infections and Outbreaks Research
Keywords
SARS-CoV-2, clinical course, pneumonia, emerging infectious diseases, public health coordination, clinical management
MeSH terms
Betacoronavirus, COVID-19, SARS-CoV-2, COVID-19 Testing, Adult, Blood Chemical Analysis, China, Humans, Lung, Male, Pneumonia, Viral, Radiography, Thoracic, Travel, United States, Genome, Viral, Sequence Analysis, DNA, Coronavirus Infections, Disease Progression, Clinical Laboratory Techniques

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