Implicit bias and the gender inequity in liver transplantation
Open accessAbstract
Women with cirrhosis awaiting liver transplantation are less likely to receive a transplant and more likely to die than men. While differences in body size and estimation of kidney function are well-studied contributors to this gender inequity, what has received relatively little mention as a potential contributing factor is the possibility of implicit bias. Implicit bias is defined as "any unconscious or unacknowledged preference that affects a person's outlook or behavior." The undeniable presence of implicit bias, a factor that is known to negatively influence health outcomes for women, within our health care system means that patients interacting within our transplant system may still experience unequal treatment despite our best efforts to modify the allocation system at the national level. Awareness of this additional source of gender-based disparities is the first step. In this article, we posit that implicit bias in liver transplantation may exacerbate the gender inequity in transplant access and provide examples in the literature to support this assertion. Lastly, we offer strategies that could be applied at the individual or the healthcare delivery system levels to help reduce the influence of implicit bias on the gender inequity in liver transplantation.
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Women with cirrhosis awaiting liver transplantation are less likely to receive a transplant and more likely to die compared to men.
“Women with cirrhosis awaiting liver transplantation are less likely to receive a transplant and more likely to die compared to men85.”
From Bias recognition and mitigation strategies in artificial intelligence healthcare applications (2025) · cites this paper as [85]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Cites
Implicit bias in healthcare professionals: a systematic review
FitzGerald, C., & Hurst, S. (2017) · BMC Medical Ethics · doi:10.1186/s12910-017-0179-8 · Cited by 2,398 · see citing works
Blindspot: hidden biases of good people
(2014) · Choice Reviews Online · doi:10.5860/choice.51-5867 · Cited by 1,027 · see citing works
Patterns of implicit and explicit attitudes: I. Long-term change and stability from 2007 to 2016
Charlesworth, T. E. S., & Banaji, M. R. (2019) · Psychological Science · doi:10.1177/0956797618813087 · Cited by 466 · see citing works
FitzGerald, C., Martin, A., Berner, D., & Hurst, S. (2019) · BMC Psychology · doi:10.1186/s40359-019-0299-7 · Cited by 445 · see citing works
Disparities in Liver Transplantation Before and After Introduction of the MELD Score
Moylan, C. A. (2008) · JAMA · doi:10.1001/jama.2008.720 · Cited by 363 · see citing works
Lai, J. C., Sonnenday, C. J., Tapper, E. B., Duarte‐Rojo, A., Dunn, M. A., Bernal, W. E., Carey, E. J., Dasarathy, S., Kamath, B. M., Kappus, M. R., et al. (2019) · American Journal of Transplantation · doi:10.1111/ajt.15392 · Cited by 281 · see citing works
Self-citationEstimating Implicit and Explicit Gender Bias Among Health Care Professionals and Surgeons
Salles, A., Awad, M. M., Goldin, L. M., Krus, K. L., Lee, J. V., Schwabe, M. T., & Lai, C. K. (2019) · JAMA Network Open · doi:10.1001/jamanetworkopen.2019.6545 · Cited by 265 · see citing works
Allen, A. M., Heimbach, J. K., Larson, J. J., Mara, K. C., Kim, W. R., Kamath, P. S., & Therneau, T. M. (2018) · Transplantation · doi:10.1097/tp.0000000000002196 · Cited by 185 · see citing works
Lai, J. C., Covinsky, K. E., McCulloch, C. E., & Feng, S. (2017) · The American Journal of Gastroenterology · doi:10.1038/ajg.2017.443 · Cited by 173 · see citing works
Self-citationAssociation of Gender and Race With Allocation of Advanced Heart Failure Therapies
Breathett, K. K., Yee, E., Pool, N. M., Hebdon, M., Crist, J. D., Yee, R., Knapp, S. M., Solola, S., Luy, L. P., Herrera‐Theut, K., et al. (2020) · JAMA Network Open · doi:10.1001/jamanetworkopen.2020.11044 · Cited by 151 · see citing works
Quantifying Sex-Based Disparities in Liver Allocation
Locke, J. E., Shelton, B. A., Olthoff, K. M., Pomfret, E. A., Forde, K. A., Sawinski, D. L., Gray, M. E., & Ascher, N. L. (2020) · JAMA Surgery · doi:10.1001/jamasurg.2020.1129 · Cited by 140 · see citing works
Self-citationLai, J. C., Terrault, N. A., Vittinghoff, E., & Biggins, S. W. (2010) · American Journal of Transplantation · doi:10.1111/j.1600-6143.2010.03326.x · Cited by 130 · see citing works
Self-citationSex-Based Disparities in Liver Transplant Rates in the United States
Mathur, A. K., Schaubel, D. E., Gong, Q., Guidinger, M. K., & Merion, R. M. (2011) · American Journal of Transplantation · doi:10.1111/j.1600-6143.2011.03498.x · Cited by 125 · see citing works
Maserejian, N. N., Link, C. L., Lutfey, K. L., Marceau, L. D., & McKinlay, J. B. (2009) · Journal of Women's Health · doi:10.1089/jwh.2008.1007 · Cited by 116 · see citing works
Decision Making in Liver Transplant Selection Committees
Volk, M. L., Biggins, S. W., Huang, M. A., Argo, C. K., Fontana, R. J., & Anspach, R. R. (2011) · Annals of Internal Medicine · doi:10.7326/0003-4819-155-8-201110180-00006 · Cited by 110 · see citing works
Sex-based disparities in delisting for being “too sick” for liver transplantation
Cullaro, G., Sarkar, M. A., & Lai, J. C. (2017) · American Journal of Transplantation · doi:10.1111/ajt.14608 · Cited by 97 · see citing works
Self-citationGender disparity in liver transplant waiting-list mortality: The importance of kidney function
Mindikoglu, A. L., Regev, A., Seliger, S. L., & Magder, L. S. (2010) · Liver Transplantation · doi:10.1002/lt.22121 · Cited by 89 · see citing works
Exception Points and Body Size Contribute to Gender Disparity in Liver Transplantation
Nephew, L. D., Goldberg, D. S., Lewis, J. D., Abt, P. L., Bryan, M., & Forde, K. A. (2017) · Clinical Gastroenterology and Hepatology · doi:10.1016/j.cgh.2017.02.033 · Cited by 84 · see citing works
Deutsch‐Link, S., Weinberg, E. M., Bittermann, T., McDougal, M., Dhariwal, A., Jones, L., Weinrieb, R. M., Banerjee, A. G., Addis, S., & Serper, M. (2020) · Liver Transplantation · doi:10.1002/lt.25975 · Cited by 82 · see citing works
U.S. NEPHROLOGISTS??? ATTITUDES TOWARDS RENAL TRANSPLANTATION: RESULTS FROM A NATIONAL SURVEY
Thamer, M., Hwang, W., Fink, N. E., Sadler, J. H., Bass, E. B., Levey, A. S., Brookmeyer, R., & Powe, N. R. (2001) · Transplantation · doi:10.1097/00007890-200101270-00020 · Cited by 72 · see citing works
(2004) · PubMed Central · Cited by 66 · see citing works
Ladin, K., Emerson, J. G., Butt, Z. A., Gordon, E. J., Hanto, D. W., Perloff, J. N., Daniels, N., & Lavelle, T. A. (2018) · Journal of Medical Ethics · doi:10.1136/medethics-2017-104695 · Cited by 55 · see citing works
Champagne‐Langabeer, T., & Hedges, A. L. (2021) · BMC Medical Education · doi:10.1186/s12909-021-02601-2 · Cited by 52 · see citing works
Lipford, K. J., McPherson, L. J., Hamoda, R. E., Browne, T. A., Gander, J. C., Pastan, S. O., & Patzer, R. E. (2018) · BMC Nephrology · doi:10.1186/s12882-017-0800-6 · Cited by 44 · see citing works
Time for Action to Address the Persistent Sex-Based Disparity in Liver Transplant Access
Verna, E. C., & Lai, J. C. (2020) · JAMA Surgery · doi:10.1001/jamasurg.2020.1126 · Cited by 32 · see citing works
Self-citationObesity and gender-biased access to deceased donor kidney transplantation
Ladhani, M., Craig, J. C., & Wong, G. (2019) · Nephrology Dialysis Transplantation · doi:10.1093/ndt/gfz100 · Cited by 29 · see citing works
Flagged first, then by citations
1 of the 27 references couldn’t be matched to a known paper.
Research works printed but not linked: 1
- [9]Bargh JA. Conditional automaticity: Varieties of automatic influence in social perception and cognition. Unintended Thought. The Guilford Press; 1989: 3– 51.
Cited by
Sorted by citations
Bias recognition and mitigation strategies in artificial intelligence healthcare applications
Hasanzadeh, F., Josephson, C. B., Waters, G., Adedinsewo, D., Azizi, Z., & White, J. A. (2025) · npj Digital Medicine · doi:10.1038/s41746-025-01503-7 · Cited by 320 · see citing works
Lucey, M. R., Furuya, K. N., & Foley, D. P. (2023) · New England Journal of Medicine · doi:10.1056/nejmra2200923 · Cited by 182 · see citing works
A translational perspective towards clinical AI fairness
Liu, M., Ning, Y., Teixayavong, S., Mertens, M., Xu, J., Ting, D. S. W., Cheng, L. T.-E., Ong, J. C. L., Teo, Z. L., Tan, T. F., et al. (2023) · npj Digital Medicine · doi:10.1038/s41746-023-00918-4 · Cited by 82 · see citing works
Sawinski, D. L., Lai, J. C., Pinney, S., Gray, A., Jackson, A. M., Stewart, D. E., Levine, D. J., Locke, J. E., Pomposelli, J. J., Hartwig, M. G., et al. (2023) · American Journal of Transplantation · doi:10.1016/j.ajt.2022.11.008 · Cited by 38 · see citing works
Self-citationActionable Solutions to Achieve Health Equity in Chronic Liver Disease
Jones, P. D., Lai, J., Bajaj, J., & Kanwal, F. (2023) · Clinical Gastroenterology and Hepatology · doi:10.1016/j.cgh.2023.03.043 · Cited by 22 · see citing works
Self-citationGeographic disparities in access to liver transplant for advanced cirrhosis: Time to ring the alarm!
Bajaj, J. S., Choudhury, A. K., Kumaran, V., Wong, F., Seto, W., Álvares‐da‐Silva, M. R., Desalgn, H., Hayes, P. C., Idılman, R., Topazian, M. D., et al. (2024) · American Journal of Transplantation · doi:10.1016/j.ajt.2024.02.018 · Cited by 19 · see citing works
Sex and Size Disparities in Access to Liver Transplant for Patients With Hepatocellular Carcinoma
Cron, D. C., Mazur, R. D., Bhan, I., Adler, J. T., & Yeh, H. (2024) · JAMA Surgery · doi:10.1001/jamasurg.2024.3498 · Cited by 17 · see citing works
Kling, C. E., Biggins, S. W., Bambha, K. M., Feld, L. D., Perkins, J. H., Reyes, J. D., & Perkins, J. D. (2023) · JAMA Surgery · doi:10.1001/jamasurg.2023.0191 · Cited by 17 · see citing works
Liver transplantation for people of minoritised sexual and gender identities in the USA
Lee, T.-H. “., Duong, N. K., Sutha, K., Simonetto, D. A., & Paul, S. (2023) · The Lancet. Gastroenterology & hepatology · doi:10.1016/s2468-1253(23)00238-8 · Cited by 13 · see citing works
Cron, D. C., Braun, H. J., Ascher, N. L., Yeh, H., Chang, D. C., & Adler, J. T. (2023) · Annals of Surgery · doi:10.1097/sla.0000000000005933 · Cited by 9 · see citing works
Agudile, E. P., Vega, E. A., Salirrosas, O., Agudile, U. M., Chirban, A. M., Lathan, C. S., Sorescu, G. P., Odisio, B. C., Panettieri, E., & Conrad, C. H. (2024) · Journal of Gastrointestinal Surgery · doi:10.1016/j.gassur.2024.05.015 · Cited by 7 · see citing works
Lee, T.-H. “., Paul, S., & Kahn, J. A. (2023) · American Journal of Transplantation · doi:10.1016/j.ajt.2023.09.013 · Cited by 7 · see citing works
Utility and bias in psychosocial evaluations for transplant listing
Ladin, K. (2025) · Current Opinion in Organ Transplantation · doi:10.1097/mot.0000000000001198 · Cited by 5 · see citing works
Wiering, L., Aigner, A., van Rosmalen, M., Globke, B., Dziodzio, T., Raschzok, N., Demir, M., Schöning, W., Tacke, F., Reinke, P., et al. (2025) · Transplant International · doi:10.3389/ti.2025.13844 · Cited by 5 · see citing works
Initial Imaging for Adults With Maxillofacial Trauma in a National Claims Database
Wong, G. C., Song, Y., SAMPSON, R. D., Wang, L., & Chung, K. C. (2026) · JAMA Network Open · doi:10.1001/jamanetworkopen.2025.58293 · Cited by 3 · see citing works
Equity in liver transplantation: are we any closer?
Ogundolie, M., Chan, N. W., & McElroy, L. M. (2023) · Current Opinion in Organ Transplantation · doi:10.1097/mot.0000000000001085 · Cited by 3 · see citing works
Xenotransplantation and Clinical Ethics
Potter, J., & White, L. C. (2023) · Springer eBooks · doi:10.1007/978-3-031-29071-8_4 · Cited by 3 · see citing works
Lin, Y. (2023) · SSM - Qualitative Research in Health · doi:10.1016/j.ssmqr.2023.100346 · Cited by 3 · see citing works
Fernández‐Alonso, V., Moro‐Tejedor, M. N., Pérez-Gómez, M., Leñero‐Cirujano, M., & Hernández-Matías, A. M. (2024) · Healthcare · doi:10.3390/healthcare13010024 · Cited by 3 · see citing works
Addressing sex-based disparities in liver transplantation
Hundt, M. A., Tien, C., & Kahn, J. A. (2022) · Current Opinion in Organ Transplantation · doi:10.1097/mot.0000000000001040 · Cited by 3 · see citing works
The sex disparity in liver transplantation
Hogen, R., Witt, M. H., & Dhanireddy, K. K. (2023) · Current Opinion in Organ Transplantation · doi:10.1097/mot.0000000000001081 · Cited by 3 · see citing works
Gender disparities in liver transplantation
Govalan, R., Singh, S., & Sharma, P. (2025) · Indian Journal of Gastroenterology · doi:10.1007/s12664-025-01839-8 · Cited by 2 · see citing works
Decision-Making in Transplant Candidate Selection Committees
Kim, C. H., Lee, F. G., Beaman, L. R., Meyer, L. E., & Diwan, T. S. (2025) · Mayo Clinic Proceedings · doi:10.1016/j.mayocp.2025.04.022 · Cited by 1 · see citing works
Cozzi, E., Carella, C., Puoti, F., Masiero, L., Forsythe, J., Manas, D., Nathan, N., Kamiński, A., Álvarez, M. F., Carmona, M., et al. (2026) · Transplant International · doi:10.3389/ti.2026.15711 · Cited by 1 · see citing works
Schiano, T. D., & Ganger, D. R. (2024) · Liver Transplantation · doi:10.1097/lvt.0000000000000392
Diversity, equity, inclusion, and belonging in organ transplantation
Nonterah, C. W., Spivey, C. A., Hayde, N. A., Chisholm‐Burns, M. A., Giusti, S. G., Kelly, B. S., & Lee, T.-H. “. (2025) · American Journal of Transplantation · doi:10.1016/j.ajt.2025.05.001
Trends in Liver Transplantation for Acute Liver Failure in a Spanish Multicenter Cohort
Amiel, I. C., Delgado, S. M., Robledo, A. B., Senosiáin, M., Martín‐Mateos, R., Almohalla, C., Diéguez, M. L. G., Pérez, S. L., Ferreiro, A. O., Soler, M. R., et al. (2025) · Transplant International · doi:10.3389/ti.2025.15185
Outcomes in adult liver transplant patients receiving recombinant herpes zoster vaccine
Henkes, N. C., Heien, H. C., Inselman, J., Farraye, F. A., & Keaveny, A. P. (2026) · Vaccine · doi:10.1016/j.vaccine.2026.128859
Yang, X., Li, R., & Luo, W. (2026) · iScience · doi:10.1016/j.isci.2026.117804
Artificial Intelligence in Liver Transplantation: The Next Frontier in Clinical Decision-Making
Deshmukh, A., Avalareddy, A., & Asthana, S. (2026) · Journal of Clinical and Experimental Hepatology · doi:10.1016/j.jceh.2026.103691
- Authors
- Lai, J. C., Pomfret, E. A., & Verna, E. C.
- Affiliations
- University of California, San Francisco (US)
- University of Colorado Denver (US)
- Columbia University (US)
- Corresponding author
- Lai, Jennifer C.
- Pomfret, Elizabeth A.
- Venue
- American Journal of Transplantation
- Publisher
- Elsevier BV
- Published
- 2022-06
- Volume
- 22
- Issue
- 6
- Pages
- 1515-1518
- ISSN
- 1600-6135 (ISSN-L)
- PMC
- PMC13614513
- OpenAlex
- W4210389457
- Cited by
- 30
- References
- 27
- Citations by year
- 2026: 5 · 2025: 7 · 2024: 5 · 2023: 12 · 2022: 1
- FWCI
- 5.52
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Licence
- Locations
- American Journal of Transplantation (publishedVersion, cc-by-nc-nd)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Institute on Aging (R01AG059183, P30 DK026743)
- Topics
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Sex and Gender in Healthcare
- Social Sciences › Gender Studies › Diversity and Career in Medicine
- Health Sciences › Medicine › Surgery › Organ Transplantation Techniques and Outcomes
- Keywords
- implicit bias, gender inequity, liver transplantation, access to transplantation, gender disparities in health care, organ allocation
- MeSH terms
- Bias, Implicit, Delivery of Health Care, Female, Humans, Male, Liver Transplantation, Healthcare Disparities
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review