The DOI matches its Crossref record; 53 of the 53 references it cites were found in a registry or an index.
The epidemiology of anaphylaxis in Europe: a systematic review
Open accessAbstract
BACKGROUND: Anaphylaxis is an acute, potentially fatal, multi-organ system, allergic reaction caused by the release of chemical mediators from mast cells and basophils. Uncertainty exists around epidemiological measures of incidence and prevalence, risk factors, risk of recurrence, and death due to anaphylaxis. This systematic review aimed to (1) understand and describe the epidemiology of anaphylaxis and (2) describe how these characteristics vary by person, place, and time. METHODS: Using a highly sensitive search strategy, we identified systematic reviews of epidemiological studies, descriptive and analytical epidemiological investigations, and studies involving analysis of routine data. RESULTS: Our searches identified a total of 5,843 potentially eligible studies, of which 49 satisfied our inclusion criteria. Of these, three were suitable for pooled estimates of prevalence. The incidence rates for all-cause anaphylaxis ranged from 1.5 to 7.9 per 100,000 person-years. These data indicated that an estimated 0.3% (95% CI 0.1-0.5) of the population experience anaphylaxis at some point in their lives. Food, drugs, stinging insects, and latex were the most commonly identified triggers. CONCLUSIONS: Anaphylaxis is a common problem, affecting an estimated 1 in 300 of the European population at some time in their lives. Future research needs to focus on better understanding of the trends across Europe and identifying those most likely to experience fatal reactions.
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Self-citationPreferred reporting items for systematic reviews and meta-analyses: The PRISMA statement
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Self-citationApproximate is Better than “Exact” for Interval Estimation of Binomial Proportions
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The diagnosis and management of anaphylaxis: An updated practice parameter
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Anaphylactic and Anaphylactoid Reactions Occurring during Anesthesia in France in 1999–2000
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Self-citationAnaphylaxis during anesthesia in France: An 8-year national survey
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EAACI Food Allergy and Anaphylaxis Guidelines: Diagnosis and Management of Food Allergy
Muraro, A., Werfel, T., Hoffmann-Sommergruber, K., Roberts, G., Beyer, K., Bindslev-Jensen, C., Cardona, V., Dubois, A., duToit, G., Eigenmann, P., et al. (2014) · Allergy · doi:10.1111/all.12429 · Cited by 1,116
Self-citationSchuch, A., & Brockow, K. (2017) · Immunology and Allergy Clinics of North America · doi:10.1016/j.iac.2016.08.017 · Cited by 88
Anaphylaxis as a clinical manifestation of clonal mast cell disorders
Matito, A., Alvarez-Twose, I., Morgado, J. M., Sánchez-Muñoz, L., Orfao, A., & Escribano, L. (2014) · Current Allergy and Asthma Reports · doi:10.1007/s11882-014-0450-8 · Cited by 51
Anaphylaxis and Mast Cell Disorders
Gülen, T., & Akin, C. (2022) · Immunology and Allergy Clinics of North America · doi:10.1016/j.iac.2021.09.007 · Cited by 51
Low frequency of IgE-mediated food hypersensitivity in mastocytosis
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Metadata
- Authors
- Panesar, S. S., Javad, S., de Silva, D., Nwaru, B. I., Hickstein, L., Muraro, A., Roberts, G., Worm, M., Bilò, M. B., Cardona, V., Dubois, A. E. J., Dunn Galvin, A., Eigenmann, P., Fernandez-Rivas, M., Halken, S., Lack, G., Niggemann, B., Santos, A. F., Vlieg-Boerstra, B. J., Zolkipli, Z. Q., Sheikh, A., & the EAACI Food Allergy and Anaphylaxis Group
- Venue
- Allergy
- Publisher
- Wiley
- Published
- 2013-10-14
- Volume
- 68
- Issue
- 11
- Pages
- 1353-1361
- ISSN
- 0105-4538 (ISSN-L)
- OpenAlex
- W2064675002
- Cited by
- 417
- References
- 53
- FWCI
- 4.16
- Type
- journal article
- Language
- en
- Open access
- green
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- Panesar, S. S., Javad, S., de Silva, D., Nwaru, B. I., Hickstein, L., Muraro, A., Roberts, G., Worm, M., Bilò, M. B., Cardona, V., Dubois, A. E. J., Dunn Galvin, A., Eigenmann, P., Fernandez-Rivas, M., Halken, S., Lack, G., Niggemann, B., Santos, A. F., Vlieg-Boerstra, B. J., . . . the EAACI Food Allergy and Anaphylaxis Group. (2013). The epidemiology of anaphylaxis in Europe: a systematic review. Allergy. https://doi.org/10.1111/all.12272
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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