The DOI matches its Crossref record; 10 of the 10 references it cites were found in a registry or an index.
Risk factors for intensive care unit-acquired weakness: A systematic review and meta-analysis
Open accessAbstract
Intensive care unit-acquired weakness (ICUAW) occurs frequently in the context of critical illness without alternative plausible cause and specific treatment options, and it is important to identify and summarize the independent risk factors for ICUAW. PubMed, Embase, Central, China Biological Medicine, China National Knowledge Infrastructure, VIP and Wanfang databases were searched from database inception until 10 July 2017. Prospective cohort studies on adult ICU patients who were diagnosed with ICUAW using either clinical or electrophysiological criteria were selected. Meta-analysis was performed using Stata version 12.0. The results were analysed using odds ratios (OR) and 95% confidence intervals (CI). Data were pooled using a random-effects model, and heterogeneity was assessed using the I2 statistic. Qualitative analysis and systematic review were used for risk factors that were deemed inappropriate to combine. Fourteen prospective cohort studies were included in this review. The meta-analysis showed that Acute Physiology and Chronic Health Evaluation II score (OR, 1.05; 95%CI, 1.01-1.10), neuromuscular blocking agents (OR, 2.03; 95%CI, 1.22-3.40) and aminoglycosides (OR, 2.27; 95%CI, 1.07-4.81) were found to be significantly associated with ICUAW. Other risk factors, including female, multiple organ failure, systemic inflammatory response syndrome, sepsis, electrolyte disturbances, hyperglycaemia, hyperosmolarity, high lactate level, duration of mechanical ventilation, parenteral nutrition and use of norepinephrine, were statistically significant on multivariable analysis in each single studies. This review provides a number of independent risk factors for ICUAW, which should be guided for early prediction and prevention of the disorder.
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Vanhorebeek, I., Latronico, N., & Van den Berghe, G. (2020) · Intensive Care Medicine · doi:10.1007/s00134-020-05944-4 · Cited by 717
Muscular weakness and muscle wasting in the critically ill
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Out of Control: The Role of the Ubiquitin Proteasome System in Skeletal Muscle during Inflammation
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Metadata
- Authors
- Yang, T., Li, Z., Jiang, L., Wang, Y., & Xi, X.
- Venue
- Acta Neurologica Scandinavica
- Publisher
- Wiley
- Published
- 2018-05-29
- Volume
- 138
- Issue
- 2
- Pages
- 104-114
- ISSN
- 0001-6314 (ISSN-L)
- OpenAlex
- W2806967749
- Cited by
- 202
- References
- 10
- FWCI
- 2.83
- Type
- journal article
- Language
- en
- Open access
- bronze
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- Yang, T., Li, Z., Jiang, L., Wang, Y., & Xi, X. (2018). Risk factors for intensive care unit-acquired weakness: A systematic review and meta-analysis. Acta Neurologica Scandinavica. https://doi.org/10.1111/ane.12964
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