International study on antidepressant prescription pattern at 40 major psychiatric institutions and hospitals in A sia: A 10‐year comparison study
Abstract
Introduction: Research in prescription pattern of antidepressants in A sia is lacking. This study aims to compare the antidepressants prescription pattern in A sia in 2003–2004 and 2013. Methods: The R esearch in E ast A sia P sychotropic P rescription P attern on A ntidepressants ( REAP‐AD ) had worked collaboratively in 2003–2004 ( REAP‐AD 2003/2004) and 2013 ( REAP‐AD 2013) to study the prescription pattern of antidepressants in A sia. The REAP‐AD 2013 study was conducted in C hina, H ong K ong, I ndia, I ndonesia, J apan, Korea, M alaysia, S ingapore, T aiwan, and T hailand using a unified research protocol and questionnaire. Results: Forty psychiatric centers participated in REAP‐AD 2013 and a total of 2,319 patients receive antidepressants were analyzed. In 2013, 39.6% of the antidepressant prescriptions were for diagnoses other thandepressive disorder compared with 38.4% in REAP‐AD 2003/2004. Out of all the antidepressants listed in the A natomical T herapeutic C hemical C lassification index by the W orld H ealth O rganization C ollaborating C enter for D rug S tatistics M ethodology ( O slo), only 38% antidepressants were prescribed in participating centers in 2013 compared with 46% in REAP‐AD 2003/2004. The selective serotonin reuptake inhibitors were the most common antidepressant prescribed in the participating centers, which was similar to the 2003–2004 survey. Prescription of newer generation antidepressants had increased in 2013 survey; on the contrary, prescription of tricyclic antidepressants had reduced. Discussion: This study has contributed significantly in relation to the changing patterns of antidepressant use in all the participating Asian centers in the last 10 years. The findings are important in shaping optimal antidepressant prescription and future policy making.
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In Asia, SSRIs dominated in almost every country, but particular prescription preferences differed from country to country.
“In Asia, though SSRIs dominated in almost every country, the particular prescription preferences were different from country to country (35–37).”
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- Authors
- Chee, K., Tripathi, A., Avasthi, A., Chong, M., Sim, K., Yang, S., Glover, S., Xiang, Y., Si, T., Kanba, S., He, Y., Lee, M., Chiu, H. F., Kuga, H., Mahendran, R., Udormatn, P., Kallivayalil, R. A., Tanra, A. J., Maramis, M., Shinfuku, N., Shen, W. W., Tan, C., & Sartorius, N.
- Affiliations
- Hospital Kuala Lumpur (MY)
- King George's Medical University (IN)
- Post Graduate Institute of Medical Education and Research (IN)
- Chang Gung University (TW)
- Institute of Mental Health (SG)
- Department of Pharmacy Taipei City Hospital Taipei Taiwan China
- University of Macau (MO)
- Department of Psychiatry Peking University Institute of Mental Health Beijing China
- Kyushu University (JP)
- Shanghai Mental Health Center (CN)
- Korea University (KR)
- Chinese University of Hong Kong (HK)
- National University Hospital (SG)
- Prince of Songkla University (TH)
- Pushpagiri Medical College (IN)
- Hasanuddin University (ID)
- Universitas Airlangga (ID)
- Kobe University (JP)
- Wan Fang Hospital (TW)
- National University of Singapore (SG)
- Association for the Improvement of Mental Health Programmes Geneva Switzerland
- Corresponding author
- Chee, Kok‐Yoon
- ORCID
- Venue
- Asia-Pacific Psychiatry
- Publisher
- Wiley
- Published
- 2015-02-23
- Volume
- 7
- Issue
- 4
- Pages
- 366-374
- ISSN
- 1758-5864 (ISSN-L)
- 1758-5872
- OpenAlex
- W1960040723
- Cited by
- 26
- References
- 15
- Citations by year
- 2026: 2 · 2025: 2 · 2024: 3 · 2023: 1 · 2022: 2 · 2021: 5 · 2020: 3 · 2019: 2 · 2018: 2 · 2017: 2 · 2016: 2
- FWCI
- 1.44
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Asia-Pacific Psychiatry (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Taipei City Hospital (10201-62-077)
- Topics
- Health Sciences › Medicine › Pharmacology › Treatment of Major Depression
- Social Sciences › Psychology › Social Psychology › Mental Health Treatment and Access
- Social Sciences › Psychology › Clinical Psychology › Psychological Treatments and Disorders
- Keywords
- antidepressants, selective serotonin reuptake inhibitors, tricyclic antidepressants, newer antidepressants, Asia, psychiatric hospitals, prescribing trends
- MeSH terms
- Adolescent, Adult, Aged, Aged, 80 and over, Antidepressive Agents, Antidepressive Agents, Tricyclic, Child, China, Female, Hong Kong, Humans, India, Indonesia, Japan, Malaysia, Male, Middle Aged, Practice Patterns, Physicians', Drug Prescriptions, Singapore, Taiwan, Thailand, Selective Serotonin Reuptake Inhibitors, Young Adult, Republic of Korea
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