International study on antidepressant prescription pattern at 20 teaching hospitals and major psychiatric institutions in East Asia: analysis of 1898 cases from China, Japan, Korea, Singapore and Taiwan
Open accessAbstract
Abstract The purpose of the present study was to review the prescription patterns of antidepressants in different countries in East Asia. The survey was conducted in China, Japan, Korea, Singapore and Taiwan from October 2003 to March 2004 using the unified research protocol and questionnaire. Twenty teaching hospitals and major psychiatric hospitals participated and a total of 1898 patients receiving antidepressants were analyzed. The survey provided a number of interesting characteristics on the prescription patterns of antidepressant in East Asia. Out of 56 antidepressants listed in the Anatomical Therapeutic Chemical Classification (ATC) index by the World Health Organization (WHO) Collaborating Center for Drug Statistics Methodology (Oslo), only 26 antidepressants were prescribed in participating countries in East Asia. On average 38.4% of prescriptions of antidepressants were for patients with diagnoses other than depressive disorders. The availability and commonly prescribed antidepressants varied greatly by country. The selective serotonin re‐uptake inhibitors (SSRI) and other newer antidepressants were prescribed in approximately 77.0% of all cases. At the time of the survey, only two SSRI medications were available in Japan. However, five types of SSRI were available and were often prescribed in Korea.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In Asia, SSRIs dominated in almost every country, but particular prescription preferences differed from country to country.
“In Asia, though SSRIs dominated in almost every country, the particular prescription preferences were different from country to country (35–37).”
Cites
Anderson, I. M. (2000) · Journal of Affective Disorders · doi:10.1016/s0165-0327(99)00092-0 · Cited by 940 · see citing works
MacGillivray, S., Arroll, B., Hatcher, S., Ogston, S., Reid, I., Sullivan, F., Williams, B., & Crombie, I. (2003) · BMJ · doi:10.1136/bmj.326.7397.1014 · Cited by 265 · see citing works
Differential pharmacology of newer antidepressants.
DeVane, C. L. (1998) · PubMed · Cited by 237 · see citing works
Prevalence and Predictors of Depression Treatment in an International Primary Care Study
Simon, G. E., Fleck, M. P. D. A., Lucas, R., Bushnell, D. M., & LIDO Group (2004) · American Journal of Psychiatry · doi:10.1176/appi.ajp.161.9.1626 · Cited by 218 · see citing works
Antidepressant Prescribing Practices of Outpatient Psychiatrists
Olfson, M., Marcus, S. C., Pincus, H. A., ZITO, J. M., Thompson, J. W., & Zarin, D. A. (1998) · Archives of General Psychiatry · doi:10.1001/archpsyc.55.4.310 · Cited by 161 · see citing works
Antipsychotic drug prescription for schizophrenia in East Asia: rationale for change
Chong, M., Tan, C. H., Fujii, S., Yang, S., UNGVARI, G. S., Si, T., Chung, E. K., Sim, K., Tsang, H., & Shinfuku, N. (2003) · Psychiatry and Clinical Neurosciences · doi:10.1111/j.1440-1819.2004.01194.x · Cited by 146 · see citing works
Self-citationSim, K., Su, A., Fujii, S., Yang, S., Chong, M., Ungvari, G. S., Si, T., Chung, E. K., Tsang, H., Chan, Y. H., et al. (2004) · British Journal of Clinical Pharmacology · doi:10.1111/j.1365-2125.2004.02102.x · Cited by 142 · see citing works
Self-citationWhich Factors Influence Psychiatrists’ Selection of Antidepressants?
Zimmerman, M. A., Posternak, M. A., Friedman, M. A., Attiullah, N., Baymiller, S., BOLAND, R. J., Berlowitz, S. L., Rahman, S., Uy, K. K., & Singer, S. (2004) · American Journal of Psychiatry · doi:10.1176/appi.ajp.161.7.1285 · Cited by 139 · see citing works
Increased Use of Antidepressants in Canada: 1981–2000
Hemels, M. E. H., Koren, G., & Einarson, T. R. (2002) · Annals of Pharmacotherapy · doi:10.1345/aph.1a331 · Cited by 120 · see citing works
Practice guidelines for the treatment of psychiatric disorders
James, N. M. (2008) · Australian & New Zealand Journal of Psychiatry · doi:10.1111/j.1440-1614.2001.0949d.pp.x · Cited by 110 · see citing works
Hansen, D. G. (2004) · Family Practice · doi:10.1093/fampra/cmh608 · Cited by 108 · see citing works
Are we going to increase the use of antidepressants up to that of benzodiazepines?
Ciuna, A., Andretta, M., Corbari, L., Levi, D., Mirandola, M., Sorio, A., & Barbui, C. (2004) · European Journal of Clinical Pharmacology · doi:10.1007/s00228-004-0810-8 · Cited by 87 · see citing works
Isacsson, G., Boëthius, G., Henriksson, S., Jones, J. K., & Bergman, U. (1999) · Journal of Affective Disorders · doi:10.1016/s0165-0327(98)00083-4 · Cited by 80 · see citing works
Lane, H., Lin, Y., & Chang, W. (1998) · The Journal of Clinical Psychiatry · doi:10.4088/jcp.v59n0207f · Cited by 67 · see citing works
Rosholm, J.-U., Gram, L. F., Isacsson, G., Hallas, J., & Bergman, U. (1997) · European Journal of Clinical Pharmacology · doi:10.1007/s002280050275 · Cited by 63 · see citing works
Hansen, D. G., Søndergaard, J., Vach, W., Gram, L. F., Rosholm, J., & Kragstrup, J. (2003) · European Journal of Clinical Pharmacology · doi:10.1007/s00228-003-0593-3 · Cited by 42 · see citing works
Variations in antidepressant prescribing practice: clinical need or market influences?
Cuevas, C. D. L., Sanz, E. J., & Fuente, J. A. D. L. (2002) · Pharmacoepidemiology and Drug Safety · doi:10.1002/pds.715 · Cited by 31 · see citing works
Questionnaire survey on the prescribing practice of Japanese psychiatrists for mood disorders.
Oshima, A., Higuchi, T., Fujiwara, Y., et al. (1999) · PubMed · Cited by 13 · see citing works
Use of Antidepressant Medications
Hamed, A., Lee, A. F., Ren, X. S., Miller, D. R., Cunningham, F., Zhang, H., & Kazis, L. E. (2004) · Medical Care · doi:10.1097/01.mlr.0000128002.73998.87 · Cited by 12 · see citing works
A case of West syndrome well controlled by very short and low‐dose ACTH therapy
Kimura, M., Miyamoto, S., Sejima, H., et al. (1999) · Psychiatry and Clinical Neurosciences · doi:10.1046/j.1440-1819.1999.00473.x · Cited by 4 · see citing works
Sugahara, H., Tokunaga, S., Kondo, T., et al. (2005) · doi:10.1185/135525705x40418 · Cited by 3 · see citing works
Flagged first, then by citations
Cited by
Sorted by citations
Luo, Y., Kataoka, Y., Ostinelli, E. G., Cipriani, A., & Furukawa, T. A. (2020) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2020.00035 · Cited by 206 · see citing works
Horn, S. R., Long, M. M., Nelson, B. W., Allen, N. B., Fisher, P. A., & Byrne, M. L. (2018) · Brain, Behavior, and Immunity · doi:10.1016/j.bbi.2018.06.016 · Cited by 129 · see citing works
Escitalopram: A Review of its Use in the Management of Major Depressive Disorder in Adults
Garnock-Jones, K. P., & McCormack, P. L. (2010) · CNS Drugs · doi:10.2165/11204760-000000000-00000 · Cited by 66 · see citing works
IPS multicentric study: Antidepressant prescription patterns
Grover, S., Avasth, A., Kalita, K., Dalal, P., Rao, G., Chadda, R., Lakdawala, B., Bang, G., Chakraborty, K., Kumar, S., et al. (2013) · Indian Journal of Psychiatry · doi:10.4103/0019-5545.105503 · Cited by 53 · see citing works
Chee, K., Tripathi, A., Avasthi, A., Chong, M., Sim, K., Yang, S., Glover, S., Xiang, Y., Si, T., Kanba, S., et al. (2015) · Asia-Pacific Psychiatry · doi:10.1111/appy.12176 · Cited by 26 · see citing works
Self-citationA systematic review of Chinese randomized clinical trials of SSRI treatment of depression
Zhang, Y., Becker, T., Ma, Y., & Koesters, M. (2014) · BMC Psychiatry · doi:10.1186/s12888-014-0245-4 · Cited by 8 · see citing works
- Authors
- UCHIDA, N., CHONG, M., TAN, C. H., NAGAI, H., TANAKA, M., LEE, M., FUJII, S., YANG, S., SI, T., SIM, K., WEI, H., LING, H. Y., NISHIMURA, R., KAWAGUCHI, Y., EDWARDS, G., SARTORIUS, N., & SHINFUKU, N.
- Affiliations
- Fukuoka University (JP)
- Chang Gung Memorial Hospital (TW)
- National University of Singapore (SG)
- Korea University (KR)
- Shanghai Mental Health Center (CN)
- Kyushu University (JP)
- Kobe University (JP)
- University of Geneva (CH)
- Seinan Gakuin University (JP)
- Corresponding author
- UCHIDA, NAOKI
- ORCID
- Venue
- Psychiatry and Clinical Neurosciences
- Publisher
- Wiley
- Published
- 2007-09-14
- Volume
- 61
- Issue
- 5
- Pages
- 522-528
- ISSN
- 1323-1316 (ISSN-L)
- 1440-1819
- OpenAlex
- W1994765909
- Cited by
- 56
- References
- 21
- Citations by year
- 2026: 2 · 2025: 1 · 2023: 3 · 2022: 2 · 2021: 1 · 2020: 2 · 2019: 1 · 2018: 3 · 2017: 7 · 2016: 6 · 2015: 8 · 2014: 4 · 2013: 5 · 2012: 3
- FWCI
- 1.34
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Psychiatry and Clinical Neurosciences (publishedVersion)
- PubMed (publishedVersion)
- National University of Singapore (submittedVersion)
- Topics
- Health Sciences › Medicine › Pharmacology › Treatment of Major Depression
- Social Sciences › Psychology › Social Psychology › Mental Health Treatment and Access
- Social Sciences › Psychology › Clinical Psychology › Psychological Treatments and Disorders
- Keywords
- antidepressants, selective serotonin reuptake inhibitors, depressive disorders, East Asia, cross-national comparison, psychiatric hospitals, teaching hospitals, medication use
- MeSH terms
- Adult, Antidepressive Agents, China, Cross-Sectional Studies, Cross-Cultural Comparison, Depressive Disorder, Drug Utilization, Female, Hospitals, Psychiatric, Hospitals, Teaching, Humans, Japan, Korea, Male, Middle Aged, Drug Prescriptions, Singapore, Taiwan, World Health Organization, Selective Serotonin Reuptake Inhibitors, Antidepressive Agents, Second-Generation
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
