The DOI matches its Crossref record; 16 of the 16 references it cites were found in a registry or an index.
A multicentre study to determine the value and safety of drug patch tests for the three main classes of severe cutaneous adverse drug reactions: Drug patch tests for SCAR
Abstract
BACKGROUND: Drug patch tests (PTs) can reproduce delayed hypersensitivity to drugs and entail a moderate re-exposure of patients to offending drugs. OBJECTIVES: To determine the value of PTs for identifying the responsible drug in severe cutaneous adverse drug reactions (SCARs) such as acute generalized exanthematous pustulosis (AGEP), drug reaction with eosinophilia and systemic symptoms (DRESS) and Stevens-Johnson syndrome/toxic epidermal necrolysis (SJS/TEN). METHODS: In a multicentre study, PTs were conducted on patients referred for DRESS, AGEP or SJS/TEN within 1 year of their SCAR. All drugs administered in the 2 months prior to and the week following the onset of the SCAR were tested. RESULTS: Among the 134 patients included (48 male, 86 female; mean age 51·7 years), positive drug PTs were obtained for 24 different drugs. These included positive tests for 64% (46/72) of patients with DRESS, 58% (26/45) of those with AGEP and 24% (4/17) of those with SJS/TEN, with only one relapse of AGEP. The value of PTs depended on the type of drug and the type of SCAR (e.g. carbamazepine was positive in 11/13 DRESS cases but none of the five SJS/TEN cases). PTs were frequently positive for beta lactams (22 cases), pristinamycin (11 cases) and in DRESS with pump proton inhibitors (five cases), but were usually negative for allopurinol and salazopyrin. Of 18 patients with DRESS, eight had virus reactivation and positive PTs. In DRESS, multiple drug reactivity was frequent (18% of cases), with patients remaining sensitized many years later. CONCLUSIONS: PTs are useful and safe for identifying agents inducing SCAR.
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Chung, W.-H., Hung, S.-I., Yang, J.-Y., Su, S.-C., Huang, S.-P., Wei, C.-Y., Chin, S.-W., Chiou, C.-C., Chu, S.-C., Ho, H.-C., et al. (2008) · Nature Medicine · doi:10.1038/nm.1884 · Cited by 840
General considerations for skin test procedures in the diagnosis of drug hypersensitivity
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Sidoroff, A., Dunant, A., Viboud, C. G., Halevy, S., Bavinck, J. N. B., Naldi, L., Mockenhaupt, M., Fagot, J. P., & Roujeau, J. (2007) · British Journal of Dermatology · doi:10.1111/j.1365-2133.2007.08156.x · Cited by 569
Barbaud, A., Gonçalo, M., Bruynzeel, D., & Bircher, A. (2001) · Contact Dermatitis · doi:10.1034/j.1600-0536.2001.450601.x · Cited by 498
Self-citationPicard, D., Janela, B., Descamps, V., D’Incan, M., Courville, P., Jacquot, S., Rogez, S., Mardivirin, L., Moins-Teisserenc, H., Toubert, A., et al. (2010) · Science Translational Medicine · doi:10.1126/scitranslmed.3001116 · Cited by 397
T-cell involvement in drug-induced acute generalized exanthematous pustulosis
Britschgi, M., Steiner, U. C., Schmid, S., Depta, J. P. H., Senti, G., Bircher, A., Burkhart, C., Yawalkar, N., & Pichler, W. J. (2001) · Journal of Clinical Investigation · doi:10.1172/jci12118 · Cited by 360
Peyrière, H., Dereure, O., Breton, H., Demoly, P., Cociglio, M., Blayac, J.-P., Hillaire-Buys, D., & the Network of the French Pharmacovigilance Centers (2006) · British Journal of Dermatology · doi:10.1111/j.1365-2133.2006.07284.x · Cited by 348
Epicutaneous patch testing in drug hypersensitivity syndrome (DRESS)
Santiago, F., Gonçalo, M., Vieira, R. J. D. C., Coelho, S., & Figueiredo, A. (2010) · Contact Dermatitis · doi:10.1111/j.1600-0536.2009.01659.x · Cited by 166
The danger hypothesis—potential role in idiosyncratic drug reactions
Pirmohamed, M., Naisbitt, D. J., Gordon, F., & Park, B. K. (2002) · Toxicology · doi:10.1016/s0300-483x(02)00255-x · Cited by 164
Delayed drug hypersensitivity: models of T‐cell stimulation
Adam, J., Pichler, W. J., & Yerly, D. (2011) · British Journal of Clinical Pharmacology · doi:10.1111/j.1365-2125.2010.03764.x · Cited by 163
Cited by
Johansen, J. D., Aalto‐Korte, K., Agner, T., Andersen, K. E., Bircher, A., Bruze, M., Cannavó, A., Giménez‐Arnau, A., Gonçalo, M., Goossens, A., et al. (2015) · Contact Dermatitis · doi:10.1111/cod.12432 · Cited by 1,453
Blumenthal, K. G., Peter, J. G., Trubiano, J. A., & Phillips, E. J. (2019) · The Lancet · doi:10.1016/s0140-6736(18)32218-9 · Cited by 614
Severe cutaneous adverse reactions to drugs
Duong, T. A., Valeyrie-Allanore, L., Wolkenstein, P., & Chosidow, O. (2017) · The Lancet · doi:10.1016/s0140-6736(16)30378-6 · Cited by 445
Castells, M., Khan, D. A., & Phillips, E. J. (2019) · New England Journal of Medicine · doi:10.1056/nejmra1807761 · Cited by 270
Metadata
- Authors
- Barbaud, A., Collet, E., Milpied, B., Assier, H., Staumont, D., Avenel-Audran, M., Grange, A., Amarger, S., Girardin, P., Guinnepain, M.-T., Truchetet, F., Lasek, A., Waton, J., & on behalf of the Toxidermies group of the French Society of Dermatology
- Venue
- British Journal of Dermatology
- Publisher
- Oxford University Press (OUP)
- Published
- 2013-02-28
- Volume
- 168
- Issue
- 3
- Pages
- 555-562
- ISSN
- 0007-0963 (ISSN-L)
- OpenAlex
- W1901880560
- Cited by
- 398
- References
- 16
- FWCI
- 11.36
- Type
- journal article
- Language
- en
- Open access
- closed
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- Barbaud, A., Collet, E., Milpied, B., Assier, H., Staumont, D., Avenel-Audran, M., Grange, A., Amarger, S., Girardin, P., Guinnepain, M.-T., Truchetet, F., Lasek, A., Waton, J., & on behalf of the Toxidermies group of the French Society of Dermatology. (2013). A multicentre study to determine the value and safety of drug patch tests for the three main classes of severe cutaneous adverse drug reactions: Drug patch tests for SCAR. British Journal of Dermatology. https://doi.org/10.1111/bjd.12125
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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