Multiple myeloma and family history of lymphohaematopoietic cancers: Results from the International Multiple Myeloma Consortium
Open accessAbstract
Summary: Family clusters of multiple myeloma (MM) suggest disease heritability. Nevertheless, patterns of inheritance and the importance of genetic versus environmental risk factors in MM aetiology remain unclear. We pooled data from eleven case‐control studies from the International Multiple Myeloma Consortium to characterize the association of MM risk with having a first‐degree relative with a history of a lympho‐haematapoietic cancer. Unconditional logistic regression models, adjusted for study, sex, age and education level, were used to estimate associations between MM risk and having a first‐degree relative with a history of non‐Hodgkin lymphoma, Hodgkin lymphoma, leukaemia or MM. Sex, African American race/ethnicity and age were explored as effect modifiers. A total of 2843 cases and 11 470 controls were included. MM risk was elevated in association with having a first‐degree relative with any lympho‐haematapoietic cancer (Odds Ratio (OR) = 1·29, 95% Confidence Interval (CI): 1·08–1·55). The association was particularly strong for having a first‐degree relative with MM (OR = 1·90, 95% CI: 1·26–2·87), especially among men (OR = 4·13, 95% CI: 2·17–7·85) and African Americans (OR = 5·52, 95% CI: 1·87–16·27).These results support the hypothesis that genetic inheritance plays a role in MM aetiology. Future studies are warranted to characterize interactions of genetic markers with environmental exposures.
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
The odds ratio for MM among first-degree relatives is 1.90 (95% CI: 1.26-2.87), with a stronger association among men (OR = 4.13, 95% CI: 2.17-7.85) and African Americans (OR = 5.52, 95% CI: 1.87-16.27).
“Retrospective results from the Multiple Myeloma Consortium found that the odds ratio (OR) for MM among first-degree relatives was 1.90, (95% CI: 1.26–2.87) with an especially strong association among men (OR = 4.13, 95% CI: 2.17–7.85) and African Americans (OR = 5.52, 95% CI: 1.87–16.27) [17].”
From Epidemiology, Staging, and Management of Multiple Myeloma (2021) · cites this paper as [17]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Cites
Multiple myeloma: A review of the epidemiologic literature
Alexander, D. D., Mink, P. J., Adami, H., Cole, P. T., Mandel, J. S., Oken, M. M., & Trichopoulos, D. (2007) · International Journal of Cancer · doi:10.1002/ijc.22718 · Cited by 321 · see citing works
Validation of family history data in cancer family registries
Ziogas, A., & Anton‐Culver, H. (2003) · American Journal of Preventive Medicine · doi:10.1016/s0749-3797(02)00593-7 · Cited by 241 · see citing works
Common variants at 2q37.3, 8q24.21, 15q21.3 and 16q24.1 influence chronic lymphocytic leukemia risk
Crowther-Swanepoel, D., Broderick, P., Bernardo, M. C. D., Dobbins, S. E., Torres, M. L., Mansouri, M. R., Ruíz-Ponte, C., Enjuanes, A., Rosenquist, R., Carracedo, Á., et al. (2010) · Nature Genetics · doi:10.1038/ng.510 · Cited by 224 · see citing works
Landgren, O., Kristinsson, S. Y., Goldin, L. R., Caporaso, N. E., Blimark, C. H., Mellqvist, U., Wåhlin, A., Björkholm, M., & Turesson, I. (2009) · Blood · doi:10.1182/blood-2008-12-191676 · Cited by 167 · see citing works
Common variation at 3q26.2, 6p21.33, 17p11.2 and 22q13.1 influences multiple myeloma risk
Chubb, D., Weinhold, N., Broderick, P., Chen, B., Johnson, D. C., Försti, A., Vijayakrishnan, J., Migliorini, G., Dobbins, S. E., Holroyd, A., et al. (2013) · Nature Genetics · doi:10.1038/ng.2733 · Cited by 163 · see citing works
Common variation at 3p22.1 and 7p15.3 influences multiple myeloma risk
Broderick, P., Chubb, D., Johnson, D. C., Weinhold, N., Försti, A., Lloyd, A., Olver, B. D., Ma, Y. P., Dobbins, S. E., Walker, B. A., et al. (2011) · Nature Genetics · doi:10.1038/ng.993 · Cited by 160 · see citing works
Vachon, C. M., Kyle, R. A., Therneau, T. M., Foreman, B. J., Larson, D. R., Colby, C. L., Phelps, T. K., Dispenzieri, A. A., Kumar, S. K., Katzmann, J. A., et al. (2009) · Blood · doi:10.1182/blood-2008-12-192575 · Cited by 152 · see citing works
Landgren, O., Linet, M. S., McMaster, M. L., Gridley, G., Hemminki, K., & Goldin, L. R. (2006) · International Journal of Cancer · doi:10.1002/ijc.21745 · Cited by 142 · see citing works
Reliability of Self-Reported Family History of Cancer in a Large Case–Control Study of Lymphoma
Chang, E. T., Smedby, K. E. E., Hjalgrim, H., Glimelius, B., & Adami, H. (2006) · JNCI Journal of the National Cancer Institute · doi:10.1093/jnci/djj005 · Cited by 129 · see citing works
Zahm, S. H., Weisenburger, D. D., Babbitt, P. A., Saal, R. C., Vaught, J. B., & Blair, A. E. (1992) · American Journal of Public Health · doi:10.2105/ajph.82.7.990 · Cited by 123 · see citing works
Orsi, L., Delabre, L., Monnereau, A., Delval, P., Berthou, C., Fenaux, P., Marit, G., Soubeyran, P., Huguet, F., Milpied, N. J., et al. (2008) · Occupational and Environmental Medicine · doi:10.1136/oem.2008.040972 · Cited by 123 · see citing works
Self-citationFamilial risks and temporal incidence trends of multiple myeloma
Altieri, A., Chen, B., Bermejo, J. L., Castro, F. A., & Hemminki, K. (2006) · European Journal of Cancer · doi:10.1016/j.ejca.2005.11.033 · Cited by 89 · see citing works
Kristinsson, S. Y., Björkholm, M., Goldin, L. R., Blimark, C. H., Mellqvist, U., Wåhlin, A., Turesson, I., & Landgren, O. (2009) · International Journal of Cancer · doi:10.1002/ijc.24514 · Cited by 87 · see citing works
Occupation, pesticide exposure and risk of multiple myeloma
Baris, D., Silverman, D. T., Brown, L. M., Swanson, G. M., Hayes, R. B., Schwartz, A. G., Liff, J. M., Schoenberg, J. B., Pottern, L. M., Greenberg, R. S., et al. (2004) · Scandinavian Journal of Work Environment & Health · doi:10.5271/sjweh.782 · Cited by 86 · see citing works
Greenberg, A. J., Rajkumar, S. V., & Vachon, C. M. (2012) · Blood · doi:10.1182/blood-2011-11-387324 · Cited by 80 · see citing works
Eriksson, M., & H�llberg, B. (1992) · Cancer Causes & Control · doi:10.1007/bf00051914 · Cited by 65 · see citing works
Interleukin-6-Related Genotypes, Body Mass Index, and Risk of Multiple Myeloma and Plasmacytoma
Cozen, W., Gebregziabher, M., Conti, D. V., Berg, D. J. V. D., Coetzee, G. A., WANG, S. S., Rothman, N., Bernstein, L., Hartge, P. A., Morhbacher, A., et al. (2006) · Cancer Epidemiology Biomarkers & Prevention · doi:10.1158/1055-9965.epi-06-0446 · Cited by 65 · see citing works
Self-citationGraß, S., Preuss, K., Ahlgrimm, M., Fadle, N., Regitz, E., Pfoehler, C., Murawski, N., & Pfreundschuh, M. G. (2009) · The Lancet Oncology · doi:10.1016/s1470-2045(09)70234-7 · Cited by 63 · see citing works
Phenotypic Heterogeneity in Multiple Myeloma Families
Lynch, H. T., Watson, P. A., Tarantolo, S., Wiernik, P. H., Quinn‐Laquer, B., Bergsagel, K. I., Huiart, L., Olopade, O. I., Sobol, H., Sanger, W. G., et al. (2005) · Journal of Clinical Oncology · doi:10.1200/jco.2005.10.126 · Cited by 63 · see citing works
Intratumoral neovascularization and growth pattern in early gastric carcinoma
Tomoda, M., Maehara, Y., Kakeji, Y., Ohno, S., Ichiyoshi, Y., & Sugimachi, K. (1999) · Cancer · doi:10.1002/(sici)1097-0142(19990601)85:11 · Cited by 57 · see citing works
VanValkenburg, M. E., Pruitt, G. I., Brill, I. K., Costa, L. J., Ehtsham, M., Justement, I., Innis-Shelton, R. D., Salzman, D. E., Reddy, E. S. P., Godby, K. N., et al. (2015) · Cancer Causes & Control · doi:10.1007/s10552-015-0685-2 · Cited by 51 · see citing works
Self-citationOgmundsdottir, H. M., Haraldsdóttirm, V., Jóhannesson, G. M., Ólafsdóttir, G. H., Bjarnadóttir, K., Sigvaldason, H., & Tulinius, H. (2005) · PubMed · Cited by 49 · see citing works
Familial multiple myeloma. A review of thirty-seven families
Shoenfeld, Y., Berliner, S. A., Shaklai, M., Gallant, L. A., & PINKHAS, J. (1982) · Postgraduate Medical Journal · doi:10.1136/pgmj.58.675.12 · Cited by 46 · see citing works
Ziv, E., Dean, E. W., Hu, D., Martino, A., Serie, D., Curtin, K. P., Campa, D., Aftab, B. T., Bracci, P. M., Buda, G., et al. (2015) · Nature Communications · doi:10.1038/ncomms8539 · Cited by 43 · see citing works
Self-citationKristinsson, S. Y., Goldin, L. R., Björkholm, M., Koshiol, J. E., Turesson, I., & Landgren, O. (2009) · Haematologica · doi:10.3324/haematol.2009.008979 · Cited by 37 · see citing works
McDuffie, H. H., Pahwa, P., Karunanayake, C. P., Spinelli, J. J., & Dosman, J. A. (2009) · BMC Cancer · doi:10.1186/1471-2407-9-70 · Cited by 33 · see citing works
Self-citationMultiple Myeloma and lifetime occupation: results from the EPILYMPH study
Perrotta, C., Staines, A. S., Codd, M., Kleefeld, S., Crowley, D., Mannetje, A. ’., Becker, N., Brennan, P., de Sanjosé, S., Foretová, L., et al. (2012) · Journal of Occupational Medicine and Toxicology · doi:10.1186/1745-6673-7-25 · Cited by 32 · see citing works
Self-citationBizzaro, N., & Pasini, P. (1990) · PubMed · Cited by 27 · see citing works
Variation in innate immunity genes and risk of multiple myeloma
Purdue, M. P., Qing Lan, B., Menashe, I., Zheng, T., Zhang, Y., Yeager, M., Hosgood, H. D., Zahm, S. H., Chanock, S. J., Rothman, N., et al. (2010) · Hematological Oncology · doi:10.1002/hon.954 · Cited by 26 · see citing works
Self-citationInherited predisposition to multiple myeloma
Koura, D. T., & Langston, A. A. (2013) · Therapeutic Advances in Hematology · doi:10.1177/2040620713485375 · Cited by 25 · see citing works
Familial myeloma and monoclonal gammopathy: A report of eight African American families
Jain, M. M., Ascensão, J. L., & Schechter, G. P. (2008) · American Journal of Hematology · doi:10.1002/ajh.21325 · Cited by 24 · see citing works
Camp, N. J., Werner, T. L., & Cannon‐Albright, L. (2008) · New England Journal of Medicine · doi:10.1056/nejmc081677 · Cited by 22 · see citing works
Self-citationAndreotti, G., Birmann, B. M., Roos, A. J. D., Spinelli, J., Cozen, W., Camp, N. J., Moysich, K. B., Chiu, B. C. ‐., Steplowski, E., Krzystan, J., et al. (2013) · Cancer Epidemiology Biomarkers & Prevention · doi:10.1158/1055-9965.epi-13-0334 · Cited by 20 · see citing works
Self-citationGenetic variations in multiple myeloma I: effect on risk of multiple myeloma
Vangsted, A. J., Klausen, T. W., & Vogel, U. B. (2011) · European Journal Of Haematology · doi:10.1111/j.1600-0609.2011.01700.x · Cited by 19 · see citing works
Campa, D., Martino, A., Sáinz, J., Buda, G., Jamroziak, K., Weinhold, N., Reis, R. M., García‐Sánz, R., Jurado, M., Ríos, R., et al. (2012) · British Journal of Haematology · doi:10.1111/j.1365-2141.2012.09047.x · Cited by 16 · see citing works
Casey, R., Brennan, P., Becker, N., Boffetta, P., Cocco, P., Domingo‐Doménech, E., Foretová, L., Nieters, A., de Sanjosé, S., Staines, A. S., et al. (2006) · European Journal of Cancer · doi:10.1016/j.ejca.2006.03.031 · Cited by 15 · see citing works
Self-citationZwick, C., Held, G., Auth, M., Bernal‐Mizrachi, L., Roback, J. D., Sunay, S., Iida, S., Kuroda, Y., Sakai, A., Ziepert, M., et al. (2014) · International Journal of Cancer · doi:10.1002/ijc.28731 · Cited by 14 · see citing works
Multiple Myeloma and Occupational Exposures
Ghosh, S., McLaughlin, J. R., Spinelli, J. J., Dosman, J. A., McDuffie, H. H., & Pahwa, P. (2011) · Journal of Occupational and Environmental Medicine · doi:10.1097/jom.0b013e31821a1ebb · Cited by 12 · see citing works
Self-citationFamilial monoclonal gammopathy: hyper‐responsive B cells in unaffected family members
Steingrímsdóttir, H., Einarsdottir, H., Haraldsdóttir, V., & Ogmundsdottir, H. M. (2011) · European Journal Of Haematology · doi:10.1111/j.1600-0609.2011.01593.x · Cited by 10 · see citing works
Initial Report of a Family Registry of Multiple Myeloma
Coleman, E. A., Lynch, H. T., Enderlin, C. A., Stewart, B., Thomé, S. D., Kennedy, R., Richardson-Nelson, T., & Barlogie, B. (2009) · Cancer Nursing · doi:10.1097/ncc.0b013e3181a90168 · Cited by 8 · see citing works
Measuring aspects of women's life and work for the study of variations in health
Dunnell, K., Bunting, J., Wood, R., & Babb, P. (1999) · American Journal of Industrial Medicine · doi:10.1002/(sici)1097-0274(199907)36:1 · Cited by 7 · see citing works
Self-citationAhmed, B., Estey, E. H., Manning, J. T., David, C. L., Keating, M. J., Kantarjian, H. M., & Tsimberidou, A. M. (2006) · PubMed · Cited by 7 · see citing works
Medication use and multiple myeloma risk in Los Angeles County
Nuyujukian, D. S., Voutsinas, J. M., Bernstein, L., & WANG, S. S. (2014) · Cancer Causes & Control · doi:10.1007/s10552-014-0424-0 · Cited by 5 · see citing works
Self-citationHeterogeneity of Ia antigen expression by proliferating nonlymphocytic leukemia blast cells
Taetle, R., & Honeysett, J. M. (1985) · Cancer · doi:10.1002/1097-0142(19851015)56:8 · Cited by 1 · see citing works
Flagged first, then by citations
1 of the 45 references couldn’t be matched to a known paper.
Research works printed but not linked: 1
- Howlader N Noone AM Krapcho M Garshell J Miller D Altekruse SF Kosary CL Yu M Ruhl J Tatalovich Z Mariotto A Lewis DR Chen HS Feuer EJ Cronin KA SEER Cancer Statistics Review, 1975-2011, based on November 2013 SEER data submission 2015
Cited by
Sorted by citations
Cancer statistics for African Americans, 2019
Desantis, C. E., Miller, K. D., Sauer, A. G., Jemal, A., & Siegel, R. L. (2019) · CA A Cancer Journal for Clinicians · doi:10.3322/caac.21555 · Cited by 744 · see citing works
Cancer statistics for African American/Black People 2022
Giaquinto, A. N., Miller, K. D., Tossas, K. Y., Winn, R. A., Jemal, A., & Siegel, R. L. (2022) · CA A Cancer Journal for Clinicians · doi:10.3322/caac.21718 · Cited by 576 · see citing works
Epidemiology, Staging, and Management of Multiple Myeloma
Padala, S. A., Barsouk, A., Barsouk, A., Rawla, P., Vakiti, A., Kolhe, R., Kota, V., & Ajebo, G. H. (2021) · Medical Sciences · doi:10.3390/medsci9010003 · Cited by 332 · see citing works
El-Khoury, H., Lee, D. J., Alberge, J.-B., Redd, R., Cea-Curry, C. J., Perry, J., Barr, H., Murphy, C., Sakrikar, D., Barnidge, D., et al. (2022) · The Lancet Haematology · doi:10.1016/s2352-3026(22)00069-2 · Cited by 94 · see citing works
Wei, X., Calvo-Vidal, M. N., Chen, S., Wu, G., Revuelta, M. V., Sun, J. H., Zhang, J., Walsh, M. F., Nichols, K. E., Vijai, J., et al. (2018) · Cancer Research · doi:10.1158/0008-5472.can-17-1900 · Cited by 85 · see citing works
Self-citationCancer statistics for African American and Black people, 2025
Saka, A. H., Giaquinto, A. N., McCullough, L. E., Tossas, K. Y., Star, J., Jemal, A., & Siegel, R. L. (2025) · CA A Cancer Journal for Clinicians · doi:10.3322/caac.21874 · Cited by 82 · see citing works
Dietary Pattern and Risk of Multiple Myeloma in Two Large Prospective US Cohort Studies
Lee, D. H., Fung, T. T., Tabung, F. K., Colditz, G. A., Ghobrial, I. M., ROSNER, B. A., Giovannucci, E. L., & Birmann, B. M. (2019) · JNCI Cancer Spectrum · doi:10.1093/jncics/pkz025 · Cited by 52 · see citing works
Genetic predisposition for multiple myeloma
Pertesi, M., Went, M., Hansson, M., Hemminki, K., Houlston, R. S., & Nilsson, B. (2020) · Leukemia · doi:10.1038/s41375-019-0703-6 · Cited by 43 · see citing works
Novel pedigree analysis implicates DNA repair and chromatin remodeling in multiple myeloma risk
Waller, R. G., Darlington, T. M., Wei, X., Madsen, M. J., Thomas, A., Curtin, K., Coon, H. H., Rajamanickam, V., Musinsky, J., Jayabalan, D. S., et al. (2018) · PLoS Genetics · doi:10.1371/journal.pgen.1007111 · Cited by 41 · see citing works
Self-citationGenome Instability in Multiple Myeloma: Facts and Factors
Aksenova, A. Y., Zhuk, A. S., Lada, A. G., Zotova, I. V., Stepchenkova, E. I., Kostroma, I. I., Gritsaev, S. V., & Pavlov, Y. I. (2021) · Cancers · doi:10.3390/cancers13235949 · Cited by 40 · see citing works
Addressing the disparities: the approach to the African American patient with multiple myeloma
Bhutani, M., Blue, B. J., Cole, C. E., Badros, A. Z., Usmani, S. Z., Nooka, A. K., Bernal‐Mizrachi, L., & Mikhael, J. R. (2023) · Blood Cancer Journal · doi:10.1038/s41408-023-00961-0 · Cited by 38 · see citing works
Multiple myeloma incidence and mortality trends in the United States, 1999–2020
Zhu, D. T., Park, A., Lai, A., Zhang, L., Attar, H., & Rebbeck, T. R. (2024) · Scientific Reports · doi:10.1038/s41598-024-65590-4 · Cited by 37 · see citing works
A comprehensive comparative study on LSD1 in different cancers and tumor specific LSD1 inhibitors
Dong, J., Pervaiz, W., Tayyab, B., Li, D., Kang, L., Zhang, H., Gong, H., Ma, X., Li, J., Agboyibor, C., et al. (2022) · European Journal of Medicinal Chemistry · doi:10.1016/j.ejmech.2022.114564 · Cited by 35 · see citing works
Clay‐Gilmour, A., Hildebrandt, M. A. T., Brown, E. E., Hofmann, J. N., Spinelli, J. J., Giles, G. G., Cozen, W., Bhatti, P., Wu, X., Waller, R. G., et al. (2020) · Blood Advances · doi:10.1182/bloodadvances.2020001435 · Cited by 27 · see citing works
Self-citationOccupational exposure to pesticides and multiple myeloma in the AGRICAN cohort
AGRICAN-Group, Tual, S., Busson, A., Boulanger, M., Renier, M. M., Piel, C., Pouchieu, C., Pons, R., Perrier, S., Levêque-Morlais, N., et al. (2019) · Cancer Causes & Control · doi:10.1007/s10552-019-01230-x · Cited by 24 · see citing works
Self-citationVachon, C. M., Murray, J. D., Allmer, C., Larson, D. R., Norman, A. D., Sinnwell, J. P., Dispenzieri, A. A., Kleinstern, G., Visram, A., Kyle, R. A., et al. (2022) · Blood Advances · doi:10.1182/bloodadvances.2021006201 · Cited by 16 · see citing works
Circulating resistin levels and risk of multiple myeloma in three prospective cohorts
Santo, L., Teras, L. R., Giles, G. G., Weinstein, S. J., Albanes, D., Wang, Y., Pfeiffer, R. M., Qing Lan, B., Rothman, N., Birmann, B. M., et al. (2017) · British Journal of Cancer · doi:10.1038/bjc.2017.282 · Cited by 16 · see citing works
Self-citationUnraveling Obesity and Multiple Myeloma: Insights from Epidemiology and Molecular Mechanisms
Manna, L., Gelsomino, L., Martino, E. A., Gentile, M., Andò, S., Bonofiglio, D., Giordano, C., Catalano, S., & Barone, I. (2025) · Current Obesity Reports · doi:10.1007/s13679-025-00644-w · Cited by 17 · see citing works
Computational Model of Progression to Multiple Myeloma Identifies Optimum Screening Strategies
Altrock, P. M., Ferlic, J., Galla, T., Tomasson, M. H., & Franziska Michor, A. (2018) · JCO Clinical Cancer Informatics · doi:10.1200/cci.17.00131 · Cited by 15 · see citing works
Risk of MGUS in relatives of multiple myeloma cases by clinical and tumor characteristics
Clay‐Gilmour, A., Kumar, S. K., Rajkumar, S. V., Rishi, A. R., Kyle, R. A., Katzmann, J. A., Murray, D. L., Norman, A. D., Greenberg, A. J., Larson, D. R., et al. (2018) · Leukemia · doi:10.1038/s41375-018-0246-2 · Cited by 15 · see citing works
Familial Risk and Heritability of Hematologic Malignancies in the Nordic Twin Study of Cancer
Clemmensen, S. B., Harris, J. R., Mengel‐From, J., Bonat, W. H., Frederiksen, H., Kaprio, J. A., & Hjelmborg, J. (2021) · Cancers · doi:10.3390/cancers13123023 · Cited by 13 · see citing works
Alcohol and tobacco use and risk of multiple myeloma: A case‐control study
Cheah, S., Bassett, J. K., Bruinsma, F., Cozen, W., Hopper, J. L., Jayasekara, H., Joshua, D., MacInnis, R. J., Prince, H. M., Vajdic, C. M., et al. (2021) · eJHaem · doi:10.1002/jha2.337 · Cited by 10 · see citing works
Self-citationLim, S. M., Wijeratne, N. G., Choy, K. W., Nguyen, T. T. H., Setiawan, L., & Loh, T. P. (2023) · Critical Reviews in Clinical Laboratory Sciences · doi:10.1080/10408363.2023.2257306 · Cited by 10 · see citing works
Geospatial analysis of population-based incidence of multiple myeloma in the United States
Cheung, J. T. H., Zhang, W., & Chiu, B. C. ‐. (2023) · Cancer Epidemiology · doi:10.1016/j.canep.2023.102343 · Cited by 7 · see citing works
Self-citationDumontet, C., Demangel, D., Galia, P., Karlin, L., Roche, L., Fauvernier, M., Golfier, C., Laude, M., Leleu, X. P., Rodon, P., et al. (2023) · American Journal of Hematology · doi:10.1002/ajh.26785 · Cited by 7 · see citing works
FaMMily Affairs: Dissecting inherited contributions to multiple myeloma risk
Bodnar, S., Brander, T., Gold, J., Iverson, A. A., Laganà, A., Onel, K., Jagannath, S., Parekh, S. S., & Thibaud, S. (2024) · Seminars in Hematology · doi:10.1053/j.seminhematol.2024.11.006 · Cited by 7 · see citing works
Sequencing at lymphoid neoplasm susceptibility loci maps six myeloma risk genes
Waller, R. G., Klein, R. J., Vijai, J., McKay, J., Clay‐Gilmour, A., Wei, X., Madsen, M. J., Sborov, D. W., Curtin, K. P., Slager, S. L., et al. (2021) · Human Molecular Genetics · doi:10.1093/hmg/ddab066 · Cited by 7 · see citing works
Self-citationThe Epidemiology of Hodgkin Lymphoma
Cozen, W., Kavianpour, B., & Mack, T. M. (2017) · Molecular pathology library · doi:10.1007/978-3-319-68094-1_8 · Cited by 7 · see citing works
Self-citationLangseth, Ø. O., Myklebust, T. Å., Johannesen, T. B., Hjertner, Ø., & Waage, A. (2022) · European Journal Of Haematology · doi:10.1111/ejh.13757 · Cited by 7 · see citing works
Time trend and Bayesian mapping of multiple myeloma incidence in Sardinia, Italy
Broccia, G., Carter, J., Özşin‐Özler, C., Meloni, F., Pilia, I., Matteis, S. D., & Cocco, P. (2022) · Scientific Reports · doi:10.1038/s41598-022-06745-z · Cited by 7 · see citing works
Self-citationPeres, L. C., Hansen, D. K., Maura, F., & Kazandjian, D. G. (2022) · Seminars in Oncology · doi:10.1053/j.seminoncol.2022.01.011 · Cited by 6 · see citing works
Cerhan, J. R., Braggio, E., Slager, S. L., & Novak, A. J. (2017) · Springer eBooks · doi:10.1007/978-3-319-64263-5_38 · Cited by 4 · see citing works
Graaf, L. D., Bresson, M., Boulanger, M., Bureau, M., Lécluse, Y., Lebailly, P., & Baldi, I. (2024) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2024.170816 · Cited by 4 · see citing works
Epidemiology of Multiple Myeloma
Ríos, R., Rodríguez, D. S., Chang-Chan, D. Y.-L., & Sánchez, M.-J. (2019) · IntechOpen eBooks · doi:10.5772/intechopen.75396 · Cited by 4 · see citing works
Racial disparities in multiple myeloma
Tebuka, E., Rambau, P., & Rasche, L. (2025) · Blood Global Hematology · doi:10.1016/j.bglo.2025.100017 · Cited by 3 · see citing works
Waller, R. G., Madsen, M. J., Gardner, J., Sborov, D. W., & Camp, N. J. (2021) · Journal of Translational Genetics and Genomics · doi:10.20517/jtgg.2021.09 · Cited by 3 · see citing works
Self-citationHuang, X., Arora, J., Erzurumluoglu, A. M., Stanhope, S. A., Lam, D., Sciences, B. I. C. B. A. D., Arora, J., Erzurumluoglu, A. M., Lam, D., Khoueiry, P., et al. (2024) · Journal of the American Medical Informatics Association · doi:10.1093/jamia/ocae297 · Cited by 2 · see citing works
Akkuş, E., Tunçalı, T., & Beksaç, M. (2025) · Clinical Lymphoma Myeloma & Leukemia · doi:10.1016/j.clml.2025.01.011 · Cited by 2 · see citing works
Multiple Myeloma: The Role of the Primary Care Nurse Practitioner
Barber, F. D., & Mullen, E. (2017) · The Journal for Nurse Practitioners · doi:10.1016/j.nurpra.2016.12.023 · Cited by 2 · see citing works
Next Generation Sequencing in Diagnosis of Multiple MyelomaPreprint
Fazazi, I. E., Ihlal, H., Abbassi, M., Ahakoud, M., Nmer, S., Bouguenouch, L., Berrady, R., Ouldim, K., & Idrissi, M. E. A. E. (2023) · Preprints.org · doi:10.20944/preprints202307.1110.v1 · Cited by 2 · see citing works
A study to identify novel biomarkers associated with multiple myeloma
Kalarani, I. B., & Veerabathiran, R. (2023) · Siberian Journal of Oncology · doi:10.21294/1814-4861-2023-22-5-134-144 · Cited by 1 · see citing works
Pathogenic germ line variants in a prospective multicenter cohort of patients with multiple myeloma
Wiedmeier, J. E., Golafshar, M. A., Kunze, K. L., Esplin, E. D., Nussbaum, R. L., Jessen, E., Heald, B., Stewart, A. K., Samadder, N. J., Bergsagel, P. L., et al. (2024) · Blood Neoplasia · doi:10.1016/j.bneo.2024.100045 · Cited by 1 · see citing works
Sternbach, N., & Gertz, M. A. (2025) · Leukemia & lymphoma/Leukemia and lymphoma · doi:10.1080/10428194.2025.2516256 · Cited by 1 · see citing works
Zhang, H., Li, M., Zhao, L., Wang, L., & Geng, J. (2025) · Hematology · doi:10.1080/16078454.2025.2576308 · Cited by 1 · see citing works
Multiple myeloma risk linked to DNA damage response genes
Conry, M. T., Ostrovnaya, I., Kemel, Y. M., Sinha, S., Baughn, L. B., Avery, B. J., Maclachlan, K. H., Groner, V., Banaszak, L. G., Norman, A. D., et al. (2026) · Journal of Hematology & Oncology · doi:10.1186/s13045-025-01776-1 · Cited by 1 · see citing works
Self-citationAgriculture et hémopathies malignes chez l’adulte
Busson, A., Gac, A., Gruson, B., Meryet‐Figuière, M., Baldi, I., Tual, S., & Lebailly, P. (2020) · médecine/sciences · doi:10.1051/medsci/2020190 · Cited by 1 · see citing works
ABDEEN, A. M., Alagha, Z., Kinney, J., Tahboub, I. N., & Al-Astal, A. (2024) · Cureus · doi:10.7759/cureus.58066 · Cited by 1 · see citing works
El‐Khoury, H., Lee, D. J., Alberge, J.-B., Redd, R. A., Cea-Curry, C. J., Perry, J. F., Barr, H., Murphy, C., Sakrikar, D. S., Barnidge, D. R., et al. (2021) · SSRN Electronic Journal · doi:10.2139/ssrn.3978571
Meiotic drive in chronic lymphocytic leukemia compared with other malignant blood disorders
Jønsson, V., Awan, H., Jones, N. D., Johannesen, T. B., Thøgersen, K., Steig, B. Á., Andorsdóttir, G., & Tjønnfjord, G. E. (2022) · Scientific Reports · doi:10.1038/s41598-022-09602-1
CLINICOPATHOLOGICAL STUDY OF MULTIPLE MYELOMA WITH EXPRESSION OF CD56
Bhattacharyya, J., & Devi, G. (2021) · INTERNATIONAL JOURNAL OF SCIENTIFIC RESEARCH · doi:10.36106/4805826
Families with non-Hodgkin lymphoma and plasma cell dyscrasias in their pedigrees
Wiernik, P. H., & Dutcher, J. P. (2023) · Journal of Investigative Medicine · doi:10.1177/10815589231210516
Cai, H. “., Xu, X., Ji, H., Shi, Y., & Shi, X. (2023) · Russian Journal of Genetics · doi:10.1134/s1022795423110121
Huang, X., Arora, J., Erzurumluoglu, A. M., Lam, D., Sciences, B. I. –. G. C. B. A. D., Zhao, H., Ding, Z., Wang, Z., & de Jong, J. (2024) · medRxiv · doi:10.1101/2024.03.12.24304163
Donald Barceloux MD, F., & Robert B. Palmer PhD, D. (2026) · Medical Toxicology · doi:10.1002/9781119872979.ch60
Next Generation Sequencing in the Diagnosis of Multiple Myeloma
Fazazi, I. E., Ihlal, H., Ouskri, A., Nmer, S., Washenko, A., Mouhi, H. E., Abbassi, M., Ahakoud, M., Bouguenouch, L., Berrady, R., et al. (2026) · Frontiers in Bioscience-Scholar · doi:10.31083/fbs44690
Lee, D. J., Chen, W. C., Bertamini, L., El‐Khoury, H., Allam, S., Fleming, G., Alberge, J.-B., Perry, J., Davis, M. I., Lightbody, E. D., et al. (2026) · EClinicalMedicine · doi:10.1016/j.eclinm.2026.104208
- Authors
- Schinasi, L. H., Brown, E. E., Camp, N. J., Wang, S. S., Hofmann, J. N., Chiu, B. C., Miligi, L., Beane Freeman, L. E., de Sanjose, S., Bernstein, L., Monnereau, A., Clavel, J., Tricot, G. J., Atanackovic, D., Cocco, P., Orsi, L., Dosman, J. A., McLaughlin, J. R., Purdue, M. P., Cozen, W., Spinelli, J. J., & de Roos, A. J.
- Affiliations
- Drexel University (US)
- University of Alabama at Birmingham (US)
- University of Utah (US)
- Beckman Research Institute (US)
- National Cancer Institute (US)
- University of Chicago (US)
- Institute for Study and Prevention of Cancer Unit of Environmental and Occupational Health Florence Italy
- Occupational and Environmental Epidemiology Branch Division of Cancer and Genetics National Cancer Institute Rockville MD USA
- Cancer Epidemiology Research Programme Catalan Institute of Oncology Barcelona Spain
- Inserm (FR)
- University of Iowa (US)
- University of Cagliari (IT)
- University of Saskatchewan (CA)
- Public Health Ontario (CA)
- University of Southern California (US)
- BC Cancer Agency (CA)
- Department of Environmental and Occupational Health Drexel University Dornsife School of Public Health Philadelphia PA USA
- Corresponding author
- Schinasi, Leah H.
- ORCID
- Schinasi, Leah H.
- Brown, Elizabeth E.
- Camp, Nicola J.
- Wang, Sophia S.
- Hofmann, Jonathan N.
- Chiu, Brian C.
- Miligi, Lucia
- Bernstein, Leslie
- Monnereau, Alain
- Clavel, Jacqueline
- Tricot, Guido J.
- Atanackovic, Djordje
- Cocco, Pierluigi
- Orsi, Laurent
- Dosman, James A.
- McLaughlin, John R.
- Purdue, Mark P.
- Cozen, Wendy
- Spinelli, John J.
- Venue
- British Journal of Haematology
- Publisher
- Wiley
- Published
- 2016-06-22
- Volume
- 175
- Issue
- 1
- Pages
- 87-101
- ISSN
- 0007-1048 (ISSN-L)
- 1365-2141
- PMC
- PMC5035512
- OpenAlex
- W2462737759
- Cited by
- 57
- References
- 45
- Citations by year
- 2026: 4 · 2025: 6 · 2024: 7 · 2023: 8 · 2022: 8 · 2021: 9 · 2020: 3 · 2019: 4 · 2018: 4 · 2017: 4
- FWCI
- 0.57
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- British Journal of Haematology (publishedVersion)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- UNICA IRIS Institutional Research Information System (University of Cagliari) (submittedVersion)
- Funders
- National Institute of Environmental Health Sciences (R21 ES021592)
- Fondation de France
- National Cancer Institute (U54CA118948, R21CA155951, R25CA76023, R01CA186646)
- American Cancer Society (IRG60‐001‐47)
- Topics
- Health Sciences › Medicine › Hematology › Multiple Myeloma Research and Treatments
- Health Sciences › Medicine › Epidemiology › Multiple and Secondary Primary Cancers
- Health Sciences › Medicine › Pathology and Forensic Medicine › Lymphoma Diagnosis and Treatment
- Keywords
- multiple myeloma, familial aggregation, heritability, first-degree relatives, non-Hodgkin lymphoma, Hodgkin's disease, leukemia, genetic risk factors, African Americans, sex differences
- MeSH terms
- Aged, Ethnicity, Family, Female, Humans, Male, Middle Aged, Multiple Myeloma, Risk Factors, Sex Factors, Odds Ratio, Case-Control Studies, Risk Assessment, Hematologic Neoplasms, Racial Groups
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
