The DOI matches its Crossref record; 5 of the 5 references it cites were found in a registry or an index.
Transformative Role of Epigenetics in Child Development Research: Commentary on the Special Section
Open accessAbstract
Lester, Conradt, and Marsit (2016) have assembled a set of articles that bring to readers of Child Development the scope and impact of the exponentially growing research on epigenetics and child development. This commentary aims to place this work in a broader context of theory and research by (a) providing a conceptual framework for developmental scientists who may be only moderately familiar with this emergent field; (b) considering these contributions in relation to the current status of work, highlighting its transformative nature; (c) suggesting cautions to keep in mind, while simultaneously clarifying that these do not undermine important new insights; and (d) identifying the prospects for future work that builds on the progress reflected in this special section.
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“Rather, genes act as followers, not prime movers, in developmental processes.”
From Malleability, plasticity, and individuality: How children learn and develop in context1 (2019) · cites this paper as Keating, 2016
Experimental — accuracy not yet measuredThe source backs part of the claim, not all of it — or backs it for a different population, condition or comparison.
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“This process begins before conception (via parental experiences) and contributes to the transmission of behaviors and experiences to future generations (e.g., Keating, 2016;Meaney, 2010)”
From Malleability, plasticity, and individuality: How children learn and develop in context1 (2019) · cites this paper as Keating, 2016
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“As packages of biological instructions, genes require signals to determine which processes are carried out, with social and physical contexts influencing if, when, how, and which genes are expressed (Keating, 2016;Moore, 2015;Slavich & Cole, 2013).”
From Malleability, plasticity, and individuality: How children learn and develop in context1 (2019) · cites this paper as Keating, 2016
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Citations
Cites
Brain on stress: how the social environment gets under the skin
McEwen, B. S. (2012) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1121254109 · Cited by 1,200
Philosophy and the practice of Bayesian statistics
Gelman, A., & Shalizi, C. R. (2013) · British Journal of Mathematical and Statistical Psychology · doi:10.1111/j.2044-8317.2011.02037.x · Cited by 825
Reynolds, R. M. (2013) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2012.08.012 · Cited by 497
Early-life experience, epigenetics, and the developing brain
Kundakovic, M., & Champagne, F. A. (2015) · Neuropsychopharmacology · doi:10.1038/npp.2014.140 · Cited by 304
Kertes, D. A., Kamin, H. S., Hughes, D. A., Rodney, N. C., Bhatt, S., & Mulligan, C. J. (2016) · Child Development · doi:10.1111/cdev.12487 · Cited by 219
Research works printed but not linked: 29
- Barr, 2015, Decoding the non-coding genome: Elucidating genetic risk outside the coding genome, Genes, Brain, and Behavior, 10.1111/gbb.12269 · DOI
- Beach, 2016, Child Development, 87, 111, 10.1111/cdev.12486 · DOI
- Boyce, 2004, A life course approach to chronic disease epidemiology, 415, 10.1093/acprof:oso/9780198578154.003.0018 · DOI
- Boyce, 2012, Toward a new biology of social adversity, Proceedings of the National Academy of Sciences of the United States of America, 109, 17143, 10.1073/pnas.1121264109 · DOI · Paper page
- Champagne, 2013, Early environments, glucocorticoid receptors, and behavioral epigenetics, Behavioral Neuroscience, 127, 628, 10.1037/a0034186 · DOI
- Conradt, 2015, Prenatal predictors of infant self-regulation: The contributions of placental DNA methylation of NR3C1 and neuroendocrine activity, Frontiers in Behavioral Neuroscience, 9, 130, 10.3389/fnbeh.2015.00130 · DOI
- Conradt, 2016, NR3C1: The contributions of maternal sensitivity and maternal depressive symptoms to epigenetic processes and neuroendocrine functioning, Child Development, 87, 73, 10.1111/cdev.12483 · DOI
- Dolinoy, 2008, Environmental epigenomics in human health and disease, Environmental and Molecular Mutagenesis, 49, 4, 10.1002/em.20366 · DOI
- Essex, 2013, Epigenetic vestiges of early developmental adversity: Childhood stress exposure and DNA methylation in adolescence, Child Development, 84, 58, 10.1111/j.1467-8624.2011.01641.x · DOI · Paper page
- Goodrich, 2015, Quality control and statistical modeling for environmental epigenetics: A study on in utero lead exposure and DNA methylation at birth, Epigenetics, 10, 19, 10.4161/15592294.2014.989077 · DOI
- Keating, 2009, Successful societies: Institutions, cultural repertoires and population health, 53, 10.1017/CBO9780511816192.004 · DOI
- Keating, 2011, Nature and nurture in early child development
- Keating, The stress gene: The lifelong impact of early life adversity—and how to break the cycle
- Keating, 1999, Developmental health and the wealth of nations: Social, biological, and educational dynamics
- Keating, 2013, Social resilience in the neo-liberal era
- Lester, 2016, Introduction to the special section on epigenetics, Child Development, 87, 29, 10.1111/cdev.12489 · DOI
- Monk, 2012, Linking prenatal maternal adversity to developmental outcomes in infants: The role of epigenetic pathways, Developmental Psychopathology, 24, 1361, 10.1017/S0954579412000764 · DOI
- Montirosso, 2016, Serotonin transporter gene (SLC6A4) methylation associates with NICU stay and 3-month-old temperament in preterm infants, Child Development, 87, 38, 10.1111/cdev.12492 · DOI
- Nahar, 2014, Bisphenol A-associated alterations in the expression and epigenetic regulation of genes encoding xenobiotic metabolizing enzymes in human fetal liver, Environmental and Molecular Mutagenesis, 55, 184, 10.1002/em.21823 · DOI
- Naumova, 2016, Epigenetic patterns modulate the connection between developmental dynamics of parenting and offspring psychosocial adjustment, Child Development, 87, 98, 10.1111/cdev.12485 · DOI
- Parade, 2016, Methylation of the glucocorticoid receptor gene promoter in preschoolers: Links with internalizing behavior problems, Child Development, 87, 86, 10.1111/cdev.12484 · DOI
- Sen, 2015, Early life lead exposure causes gender-specific changes in the DNA methylation profile of DNA extracted from dried blood spots, Epigenomics, 7, 379, 10.2217/epi.15.2 · DOI
- Skinner, 2015, Environmental epigenetics and a unified theory of the molecular aspects of evolution: A neo-Lamarckian concept that facilitates neo-Darwinian evolution, Genome Biology and Evolution, 7, 1296, 10.1093/gbe/evv073 · DOI · Paper page
- Smearman, 2016, Oxytocin receptor genetic and epigenetic variation: Association with child abuse and adult psychiatric symptoms, Child Development, 87, 122, 10.1111/cdev.12493 · DOI · Paper page
- Steenaard, 2015, Tobacco smoking is associated with methylation of genes related to coronary artery disease, Clinical Epigenetics, 7, 54, 10.1186/s13148-015-0088-y · DOI
- Stroud, 2016, Epigenetic regulation of placental NR3C1: Mechanism underlying prenatal programming of infant neurobehavior by maternal smoking?, Child Development, 87, 49, 10.1111/cdev.12482 · DOI
- Szyf, 2013, DNA methylation, behavior and early life adversity, Journal of Genetics and Genomics, 40, 331, 10.1016/j.jgg.2013.06.004 · DOI
- Szyf, 2008, The social environment and the epigenome, Environmental and Molecular Mutagenesis, 49, 46, 10.1016/j.jgg.2013.06.004 · DOI
- Webb, 2001, Mechanisms of postnatal neurobiological development: Implications for human development, Developmental Neuropsychology, 19, 147, 10.1207/S15326942DN1902_2 · DOI · Paper page
Cited by
Sorted by citations
Malleability, plasticity, and individuality: How children learn and develop in context1
Cantor, P., Osher, D., Berg, J., Steyer, L., & Rose, T. (2019) · Applied Developmental Science · doi:10.1080/10888691.2017.1398649 · Cited by 328
“…begins before conception (via parental experiences) and contributes to the transmission of behaviors and experiences to future generations (e.g., Keating, 2016; Meaney, 2010), as well as to qualitative changes in our 2In this article, we define foundational skills according to the definition…”
Background
Metadata
- Authors
- Keating, D. P.
- Affiliations
- University of Michigan (US)
- Corresponding author
- Keating, Daniel P
- ORCID
- Keating, Daniel P
- Venue
- Child Development
- Publisher
- Oxford University Press (OUP)
- Published
- 2016-01-01
- Volume
- 87
- Issue
- 1
- Pages
- 135-142
- ISSN
- 0009-3920 (ISSN-L)
- 1467-8624
- OpenAlex
- W2335339576
- Cited by
- 21
- References
- 5
- Citations by year
- 2025: 1 · 2024: 1 · 2022: 2 · 2021: 3 · 2019: 4 · 2018: 3 · 2017: 4 · 2016: 3
- FWCI
- 0.42
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- Locations
- Child Development (publishedVersion)
- PubMed (publishedVersion)
- Deep Blue (University of Michigan) (submittedVersion)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Epigenetics and DNA Methylation
- Social Sciences › Psychology › Clinical Psychology › Child and Adolescent Psychosocial and Emotional Development
- Health Sciences › Medicine › Pediatrics, Perinatology and Child Health › Birth, Development, and Health
- Keywords
- epigenetics, developmental theory, conceptual framework, future research directions
- MeSH terms
- Child, Child Development, Humans, Epigenesis, Genetic
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