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Cited by 9Obesity, Physical Activity, DietObesity and Health PracticesBariatric Surgery and Outcomes

Distribution of comorbidities as primary diagnoses by obesity class among patients in a large US paediatric healthcare system

Nussbaum, Brandon M., Mathew, Matthew Sunil, Atem, Folefac, Barlow, Sarah E., Gupta, Olga T., Messiah, Sarah E.·2021·Clinical Obesity
DOI 10.1111/cob.12478
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Abstract

Summary: There is little documentation of the distribution of specific health conditions across obesity classes (I, II, III), especially for paediatric populations who are seen for routine care in large United States US healthcare systems. The aim of this study was to assess the odds of presenting ≥2 obesity‐related comorbidities as well as assess the overall distribution of these co‐morbidities in children by class I/II/III obesity status controlling for key sociodemographic characteristics. This retrospective (2015–2019) electronic health record review analysed 49 276 patients from the Children's Health System of Texas diagnosed with obesity‐related health conditions by obesity status (no obesity, class I, II, III). Crude and adjusted logistic regression models examined the association between obesity class and the likelihood of ≥2 comorbidities as primary diagnoses. Patients with class I obesity were 22% more likely (OR 1.22, 95% CI, 1.16, 1.27), patients with class II obesity were almost 50% more likely (OR 1.44, 95% CI, 1.35, 1.53) and those with class III obesity twice as likely (OR 2.04, 95% CI 1.91, 2.18) to be diagnosed with ≥2 comorbidities as primary diagnoses, compared with patients classified with no obesity. Children with obesity, particularly severe obesity, should be monitored closely by paediatricians for possible diagnoses of risk factors that could lead to adult chronic disease.

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  • Children and adolescents with obesity were 22-104% more likely to be diagnosed with two or more obesity-related diseases as primary diagnoses, depending upon the severity of obesity, compared with people classified as without obesity.

    “Since 2021, research in a large US paediatric health-care system reported that children and adolescents with obesity were 22–104% more likely to be diagnosed with two or more obesity-related diseases as primary diagnoses, depending upon the severity of obesity, compared with people classified as without obesity.151”

    From Definition and diagnostic criteria of clinical obesity (2025) · cites this paper as [151]

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Authors
Nussbaum, B. M., Mathew, M. S., Atem, F., Barlow, S. E., Gupta, O. T., & Messiah, S. E.
Affiliations
  • The University of Texas Health Science Center at Houston (US)
  • University of Texas Health Science Center at Dallas (US)
  • The University of Texas Southwestern Medical Center (US)
Corresponding author
Messiah, Sarah E.
ORCID
Venue
Clinical Obesity
Publisher
Wiley
Published
2021-07-12
Volume
11
Issue
5
Pages
e12478-e12478
ISSN
  • 1758-8103 (ISSN-L)
  • 1758-8111
DOI
10.1111/cob.12478
OpenAlex
W3182890604
Cited by
9
References
43
Citations by year
2026: 1 · 2025: 2 · 2022: 5 · 2021: 1
FWCI
1.30
Type
journal article
Language
en
Open access
closed
Licence
onlinelibrary.wiley.com/termsAndConditions#vor (vor)
Locations
  • Clinical Obesity (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Obesity, Physical Activity, Diet
  • Health Sciences › Health Professions › Pharmacy › Obesity and Health Practices
  • Health Sciences › Medicine › Surgery › Bariatric Surgery and Outcomes
Keywords
childhood obesity, obesity severity, obesity-related comorbidities, multiple comorbidities, primary diagnosis, morbid obesity, chronic disease risk, sociodemographic factors
MeSH terms
Adult, Child, Delivery of Health Care, Humans, Obesity, Retrospective Studies, Risk Factors, United States, Comorbidity

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