The DOI matches its Crossref record; 94 of the 94 references it cites were found in a registry or an index.
Nickel allergy and allergic contact dermatitis: A clinical review of immunology, epidemiology, exposure, and treatment
Abstract
Nickel is the most frequent cause of contact allergy worldwide and has been studied extensively. This clinical review provides an updated overview of the epidemiology, exposure sources, methods for exposure quantification, skin deposition and penetration, immunology, diagnosis, thresholds for sensitization and elicitation, clinical pictures, prevention, and treatment. The implementation of a nickel regulation in Europe led to a decrease in the prevalence of nickel allergy, and changes in the clinical picture and disease severity. Nevertheless, the prevalences of nickel allergy in the European general population are approximately 8% to 19% in adults and 8% to 10% in children and adolescents, with a strong female predominance. Well‐known consumer items such as jewellery and metal in clothing are still the main causes of nickel allergy and dermatitis, although a wide range of items for both private and occupational use may cause dermatitis. Allergic nickel dermatitis may be localized to the nickel exposure site, be more widespread, or present as hand eczema. Today, efficient methods for exposure quantification exist, and new insights regarding associated risk factors and immunological mechanisms underlying the disease have been obtained. Nevertheless, questions remain in relation to the pathogenesis, the persistent high prevalence, and the treatment of severe cases.
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Cites
European Committee for Standardization
(2014) · Dictionary Geotechnical Engineering/Wörterbuch GeoTechnik · doi:10.1007/978-3-642-41714-6_51763 · Cited by 3,300
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Self-citationEuropean Committee for Standardization (CEN)
(2022) · The Fairchild Books Dictionary of Fashion · doi:10.5040/9781501365287.967 · Cited by 1,286
Leukocyte Migration into Inflamed Tissues
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Magnusson, B., & Kligman, A. M. (1969) · Journal of Investigative Dermatology · doi:10.1038/jid.1969.42 · Cited by 927
European Food Safety Authority (EFSA)
Ramos-Peralonso, M. J. (2014) · Encyclopedia of Toxicology · doi:10.1016/b978-0-12-386454-3.00563-7 · Cited by 916
The epidemiology of contact allergy in the general population – prevalence and main findings
Thyssen, J. P., Linneberg, A., Menné, T., & Johansen, J. D. (2007) · Contact Dermatitis · doi:10.1111/j.1600-0536.2007.01220.x · Cited by 680
Self-citationThe Identification of Contact Allergens by Human Assay
Kligman, A. M. (1966) · Journal of Investigative Dermatology · doi:10.1038/jid.1966.160 · Cited by 577
Nickel and molybdenum contact allergies in patients with coronary in-stent restenosis
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Early immune events in the induction of allergic contact dermatitis
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Cited by
Ecological Impacts and Potential Hazards of Nickel on Soil Microbes, Plants, and Human Health
Rizwan, M., Usman, K., & Alsafran, M. (2024) · Chemosphere · doi:10.1016/j.chemosphere.2024.142028 · Cited by 113
Fortino, V., Wisgrill, L., Werner, P., Suomela, S., Linder, N., Jalonen, E., Suomalainen, A., Marwah, V., Kero, M., Pesonen, M., et al. (2020) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2009192117 · Cited by 99
Irfan, M., Shafeeq, A., Siddiq, U., Bashir, F., Ahmad, T., Athar, M., Butt, M. T., Ullah, S., Mukhtar, A., Hussien, M., et al. (2022) · Journal of Hazardous Materials · doi:10.1016/j.jhazmat.2022.128806 · Cited by 63
Metadata
- Authors
- Ahlström, M. G., Thyssen, J. P., Wennervaldt, M., Menné, T., & Johansen, J. D.
- Venue
- Contact Dermatitis
- Publisher
- Wiley
- Published
- 2019-07-09
- Volume
- 81
- Issue
- 4
- Pages
- 227-241
- ISSN
- 0105-1873 (ISSN-L)
- 1600-0536
- OpenAlex
- W2947126976
- Cited by
- 316
- References
- 94
- FWCI
- 29.00
- Type
- journal article
- Language
- en
- Open access
- closed
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