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Cited by 28Sports Performance and TrainingCardiovascular and exercise physiologySmoking Behavior and Cessation

The DOI matches its Crossref record; 70 of the 70 references it cites were found in a registry or an index.

Nicotine effects on exercise performance and physiological responses in nicotine‐naïve individuals: a systematic review

Johnston, Robert, Doma, Kenji, Crowe, Melissa·2018·Clinical Physiology and Functional Imaging
DOI 10.1111/cpf.12443
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Abstract

Summary: The purpose of this systematic review was to evaluate the effects of smokeless forms of nicotine on physiological responses and exercise performance. Methodology and reporting were based on the PRISMA statement. The intervention was defined as any product containing nicotine that did not require smoking. Searches were conducted across two electronic databases with supplementary approaches utilized. Studies were selected following set inclusion and exclusion criteria and checked by two independent authors. A modified PED ro scale was utilized to rate study quality with studies averaging 9·3/13. Six studies assessed exercise performance with endurance‐based parameters reported as significantly improved with nicotine in one study, while anaerobic parameters were unaffected or decreased compared to placebo except in one study which reported enhanced leg extensor torque but no effect on countermovement jump or Wingate anaerobic capacity. Sixteen of 28 studies investigating physiological responses reported that nicotine significantly increased heart rate compared to placebo or control. Blood pressure and blood flow were also reported as significantly increased in multiple studies. While there is strong evidence of nicotine‐induced changes in physiological function that would benefit physical performance, beneficial effects have only been reported on leg extensor torque and endurance performance by one study each. Subsequently, there is need for more research with strong methodological quality to definitively evaluate nicotine's potential as an ergogenic aid.

Overview

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Crossref · 10.1111/cpf.12443

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70 of 70 references verified0 citation errors · 0 not checkable

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Metadata

Authors
Johnston, R., Doma, K., & Crowe, M.
Affiliations
James Cook University (AU)
Corresponding author
Doma, Kenji
ORCID
Venue
Clinical Physiology and Functional Imaging
Publisher
Wiley
Published
2017-06-02
Volume
38
Issue
4
Pages
527-538
ISSN
  • 1475-0961 (ISSN-L)
  • 1475-097X
DOI
10.1111/cpf.12443
OpenAlex
W2620652337
Semantic Scholar
a488aaccc974733e982225837c36e0b1fecfac9f
Cited by
28
References
70
Citations by year
2026: 2 · 2025: 1 · 2024: 3 · 2023: 2 · 2022: 3 · 2021: 3 · 2020: 5 · 2019: 5 · 2018: 3 · 2017: 1
FWCI
0.72
Type
journal article
Language
en
Open access
closed
Licence
onlinelibrary.wiley.com/termsAndConditions#vor (vor)
Locations
  • Clinical Physiology and Functional Imaging (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Orthopedics and Sports Medicine › Sports Performance and Training
  • Health Sciences › Medicine › Physiology (medical) › Cardiovascular and exercise physiology
  • Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Smoking Behavior and Cessation
Keywords
nicotine, exercise performance, endurance performance, anaerobic performance, heart rate, blood pressure, blood flow, countermovement jump, Wingate test, ergogenic aids
MeSH terms
Adult, Biomechanical Phenomena, Female, Hemodynamics, Humans, Male, Muscle Contraction, Nicotine, Physical Endurance, Exercise, Muscle, Skeletal, Nicotinic Agonists, Torque, Young Adult, Performance-Enhancing Substances

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CoChat. (2026). Citation check: Nicotine effects on exercise performance and physiological responses in nicotine‐naïve individuals: a systematic review. https://app.cochat.ai/papers/10.1111/cpf.12443
The paper
Johnston, R., Doma, K., & Crowe, M. (2018). Nicotine effects on exercise performance and physiological responses in nicotine‐naïve individuals: a systematic review. Clinical Physiology and Functional Imaging. https://doi.org/10.1111/cpf.12443

Data sources

Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.