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Cited by 307

The DOI matches its Crossref record; 23 of the 23 references it cites were found in a registry or an index.

The role of astrocytes in oxidative stress of central nervous system: A mixed blessing

Open access
Chen, Yaxing, Qin, Chen, Huang, Jianhan, Tang, Xin, Liu, Chang, Huang, Keru, Xu, Jianguo, Guo, Gang, Tong, Aiping, Zhou, Liangxue·2020·Cell Proliferation
DOI 10.1111/cpr.12781
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Abstract

Central nervous system (CNS) maintains a high level of metabolism, which leads to the generation of large amounts of free radicals, and it is also one of the most vulnerable organs to oxidative stress. Emerging evidences have shown that, as the key homeostatic cells in CNS, astrocytes are deeply involved in multiple aspects of CNS function including oxidative stress regulation. Besides, the redox level in CNS can in turn affect astrocytes in morphology and function. The complex and multiple roles of astrocytes indicate that their correct performance is crucial for the normal functioning of the CNS, and its dysfunction may result in the occurrence and progression of various neurological disorders. To date, the influence of astrocytes in CNS oxidative stress is rarely reviewed. Therefore, in this review we sum up the roles of astrocytes in redox regulation and the corresponding mechanisms under both normal and different pathological conditions.

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Metadata

Authors
Chen, Y., Qin, C., Huang, J., Tang, X., Liu, C., Huang, K., Xu, J., Guo, G., Tong, A., & Zhou, L.
Venue
Cell Proliferation
Publisher
Wiley
Published
2020-02-08
Volume
53
Issue
3
Pages
e12781-e12781
ISSN
  • 0960-7722 (ISSN-L)
  • 1365-2184
DOI
10.1111/cpr.12781
OpenAlex
W3005303475
Cited by
307
References
23
FWCI
10.65
Type
journal article
Language
en
Open access
gold

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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

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