The novel Chinese coronavirus (2019-nCoV) infections: Challenges for fighting the storm.
Open accessAbstract
Since end of December 2019, a cluster of patients with pneumonia of unknown origin was reported from Wuhan, Hubei province, China.1 They shared a connection with the Huanan South China Seafood Market in Wuhan, and now it has been confirmed that the disease is caused by a novel coronavirus (provisionally named 2019-nCoV).1 As of today (30 January 2020), 7734 cases have been confirmed in China, and 90 cases have also been cumulatively reported from Taiwan, Thailand, Vietnam, Malaysia, Nepal, Sri Lanka, Cambodia, Japan, Singapore, Republic of Korea, United Arab Emirate, United States, The Philippines, India, Australia, Canada, Finland, France and Germany (Finland, France and Germany are the only European countries in which cases [n = 1, n = 5, and n = 4, respectively] have been reported up to date). According to the released news, the case rate fatality is 2.2% (170/7824).2 Coronavirus are enveloped, positive-strand RNA viruses, that may be transmitted to humans from intermediate hosts (usually peridomestic mammals) and with bats being the likely reservoir of most of them, in view of the observed virus diversity.3 The 2019-nCoV is the seventh coronavirus known to infect humans. Four (229E, NL63, OC43 and HKU1) are responsible for mild upper respiratory tract infections (common cold), whereas the severe acute respiratory syndrome coronavirus (SARS-CoV, which has been contained4) and the Middle East respiratory syndrome coronavirus (MERS-CoV) are able to cause atypical pneumonia.…
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COVID-19 is a major global health challenge due to rapid transmission and disease uncertainty, particularly at the beginning of the pandemic.
“The emergence of the novel coronavirus (COVID-19) is a major global health challenge due to the rapid transmission and disease uncertainty, particularly at the beginning of the pandemic [1, 2].”
Cites
SARS and MERS: recent insights into emerging coronaviruses
de Wit, E., van Doremalen, N., Falzarano, D., & Munster, V. J. (2016) · Nature Reviews Microbiology · doi:10.1038/nrmicro.2016.81 · Cited by 3,510 · see citing works
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The epidemiology and pathogenesis of coronavirus disease (COVID-19) outbreak
Rothan, H. A., & Byrareddy, S. N. (2020) · Journal of Autoimmunity · doi:10.1016/j.jaut.2020.102433 · Cited by 5,840 · see citing works
Physical and mental health impacts of COVID-19 on healthcare workers: A scoping review
Shaukat, N., Ali, D. M., & Razzak, J. (2020) · International Journal of Emergency Medicine · doi:10.1186/s12245-020-00299-5 · Cited by 879 · see citing works
Coronavirus disease (COVID-19): a scoping review
Lv, M., Luo, X., Estill, J., Liu, Y., Ren, M., Wang, J., Wang, Q., Zhao, S., Wang, X., Yang, S., et al. (2020) · Eurosurveillance · doi:10.2807/1560-7917.es.2020.25.15.2000125 · Cited by 122 · see citing works
Htay, M. N. N., Parial, L. L., Tolabing, M. C., Dadaczynski, K., Okan, O., Leung, A. Y. M., & Su, T. T. (2022) · PLOS ONE · doi:10.1371/journal.pone.0266276 · Cited by 78 · see citing works
Mohile, S., Dumontier, C., Mian, H., Loh, K. P., Williams, G. R., Wildes, T. M., Boyd, K., Ramsdale, E., Pyne, S., Magnuson, A., et al. (2020) · Journal of Geriatric Oncology · doi:10.1016/j.jgo.2020.04.010 · Cited by 40 · see citing works
- Authors
- Bassetti, M., Vena, A., & Giacobbe, D. R.
- Affiliations
- Ospedale Policlinico San Martino (IT)
- Corresponding author
- Bassetti, Matteo
- Venue
- European Journal of Clinical Investigation
- Publisher
- Wiley
- Published
- 2020-02-05
- Volume
- 50
- Issue
- 3
- Pages
- e13209-e13209
- ISSN
- 0014-2972 (ISSN-L)
- 1365-2362
- PMC
- PMC7163647
- OpenAlex
- W3004412595
- Cited by
- 423
- References
- 1
- Citations by year
- 2026: 5 · 2025: 12 · 2024: 27 · 2023: 26 · 2022: 59 · 2021: 96 · 2020: 197 · 2019: 1
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- European Journal of Clinical Investigation (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- CINECA IRIS Institutial Research Information System (University of Genoa) (submittedVersion)
- Topics
- Health Sciences › Medicine › Infectious Diseases › SARS-CoV-2 and COVID-19 Research
- Health Sciences › Medicine › Infectious Diseases › COVID-19 Clinical Research Studies
- Health Sciences › Medicine › Infectious Diseases › Viral Infections and Outbreaks Research
- Keywords
- SARS-CoV-2, novel coronavirus, Wuhan, virus transmission, ACE2 receptor, SARS-CoV, MERS-CoV, bats as reservoir, intermediate hosts, phylogenetic analysis, case fatality, epidemic control, public health response, travel restrictions
- MeSH terms
- Betacoronavirus, COVID-19, SARS-CoV-2, COVID-19 Testing, COVID-19 Drug Treatment, Humans, Pneumonia, Viral, Coronavirus Infections, Clinical Laboratory Techniques, Pandemics
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