Cited by 59Extracellular vesicles in diseaseDermatology and Skin DiseasesCellular transport and secretion

Exosomes in chronic inflammatory skin diseases and skin tumors

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Wang, Wen‐Ming, Wu, Chao, Jin, Hong‐Zhong·2019·Experimental Dermatology

Abstract

Exosomes are membrane vesicles of endocytic origin that can mediate communication between cells and the transport of cellular components such as microRNAs, mRNAs, proteins and DNA. Recently, exosomes have been under investigation for their significant roles in both healthy physiology and disease states. Herein, we review the role of exosomes in chronic inflammatory skin diseases and skin tumors, especially focusing on systemic lupus erythematosus, psoriasis, atopic dermatitis, bullous pemphigoid and melanoma. Moreover, we emphasize the involvement of changes in exosome cargo in the regulation of these diseases.

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Cited by

Sorted by citations

Authors
Wang, W., Wu, C., & Jin, H.
Affiliations
Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
Corresponding author
Jin, Hong‐Zhong
Venue
Experimental Dermatology
Publisher
Wiley
Published
2019-03
Volume
28
Issue
3
Pages
213-218
ISSN
  • 0906-6705 (ISSN-L)
  • 1600-0625
OpenAlex
W2905003732
Cited by
59
References
70
Citations by year
2026: 6 · 2025: 3 · 2024: 17 · 2023: 7 · 2022: 9 · 2021: 9 · 2020: 5 · 2019: 3
FWCI
0.42
Type
journal article
Language
en
Open access
Locations
  • Experimental Dermatology (publishedVersion)
  • PubMed (publishedVersion)
Funders
  • Chinese Academy of Meteorological Sciences (2017‐12M‐3‐020)
  • National Natural Science Foundation of China (81773331)
Topics
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Extracellular vesicles in disease
  • Health Sciences › Medicine › Dermatology › Dermatology and Skin Diseases
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Cell Biology › Cellular transport and secretion
Keywords
exosomes, chronic inflammatory skin disease, skin tumors, systemic lupus erythematosus, psoriasis, atopic dermatitis, bullous pemphigoid, melanoma, exosome cargo, microRNA, intercellular communication
MeSH terms
Animals, Carcinoma, Squamous Cell, Dermatitis, Atopic, Endocytosis, Humans, Inflammation, Lupus Erythematosus, Systemic, Melanoma, Pemphigoid, Bullous, Prognosis, Psoriasis, Skin, Skin Diseases, Skin Neoplasms, MicroRNAs, Exosomes

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