Burden of treatment for chronic illness: a concept analysis and review of the literature
Open accessAbstract
Context: Treatment burden, the burden associated with the treatment and management of chronic illness, has not yet been well articulated. Objective: Using Rodgers' (1989, Journal of Advanced Nursing, 14, 330–335) method of concept analysis, this review describes the ways in which treatment burden has been conceptualized to define the concept and to develop a framework for understanding its attributes, antecedents and consequences. Methods: Leading databases were searched electronically between the years 2002 and 2011. To ensure the review focused on actual observations of the concept of interest, articles that did not measure treatment burden (either qualitatively or quantitatively) were excluded. An inductive approach was used to identify themes related to the concept of treatment burden. Main results: Thirty articles, identified from 1557 abstracts, were included in the review. The attributes of treatment burden include burden as a dynamic process, as a multidimensional concept, and comprising of both subjective and objective elements. Prominent predisposing factors (antecedents) include the person's age and gender, their family circumstances, possible comorbidity, high use of medications, characteristics of treatment and their relationship with their health‐care provider. The most dominant consequences are poor health and well‐being, non‐adherence to treatment, ineffective resource use and burden on significant others. Furthermore, many of these consequences can also become antecedents, reflecting the cyclic and dynamic nature of treatment burden. Conclusion: The findings underscore the need for researchers and health‐care professionals to engage in collaborative discussions and make cooperative efforts to help alleviate treatment burden and tailor treatment regimens to the realities of people's daily lives.
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There is now a discrete body of primary research literature and systematic reviews that utilises theoretical perspectives on NPT to understand patient and caregiver experience.
“there is now a discrete body of primary research literature (e.g. [216–220]) and systematic reviews (e.g. [221–223]) that utilises these theoretical perspectives to understand patient and caregiver experience.”
From Using Normalization Process Theory in feasibility studies and process evaluations of complex healthcare interventions: a systematic review (2018) · cites this paper as [222]
The Data sources and search strategy and Family and carers sections show that this is a review addressing patient and caregiver treatment burden. But the Methods section says the review uses Rodgers’ method of concept analysis, not NPT; the References section cites an NPT-based primary study. The paper therefore fits the claim as a review of patient and caregiver experience, but not as a review that itself utilises NPT. (LLM, conf=0.86)
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“, 2021) to provide benefit in reducing symptom burden in people with POTS, either on their own or adjuvant to biomedical approaches, while ensuring that the burden of treatment does not exceed the individual’s ability to cope with this (Sav et al., 2015).”
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- Authors
- Sav, A., King, M. A., Whitty, J. A., Kendall, E., McMillan, S. S., Kelly, F., Hunter, B., & Wheeler, A. J.
- Affiliations
- Griffith University (AU)
- Corresponding author
- Sav, Adem
- ORCID
- Venue
- Health Expectations
- Publisher
- Wiley
- Published
- 2013-01-31
- Volume
- 18
- Issue
- 3
- Pages
- 312-324
- ISSN
- 1369-6513 (ISSN-L)
- 1369-7625
- PMC
- PMC5060781
- OpenAlex
- W2122615311
- Cited by
- 385
- References
- 53
- Citations by year
- 2026: 37 · 2025: 40 · 2024: 44 · 2023: 38 · 2022: 41 · 2021: 42 · 2020: 31 · 2019: 28 · 2018: 28 · 2017: 12 · 2016: 17 · 2015: 8 · 2014: 9 · 2013: 9 · 2012: 1
- FWCI
- 1.70
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Health Expectations (publishedVersion)
- Europe PMC (PubMed Central) (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- QUT ePrints (Queensland University of Technology) (submittedVersion, cc-by)
- UEA Digital Repository (University of East Anglia) (submittedVersion)
- Research Bank (Australian Catholic University) (submittedVersion)
- Griffith Research Online (submittedVersion)
- Funders
- Queensland Health
- Australian Government
- Pharmacy Guild of Australia
- Griffith University
- Queensland Government
- Topics
- Health Sciences › Medicine › Epidemiology › Chronic Disease Management Strategies
- Health Sciences › Medicine › Family Practice › Medication Adherence and Compliance
- Health Sciences › Medicine › Geriatrics and Gerontology › Pharmaceutical Practices and Patient Outcomes
- Keywords
- treatment burden, chronic disease, conceptual analysis, medication adherence, medication use, comorbidities, family burden, patient well-being, resource utilization (health care)
- MeSH terms
- Chronic Disease, Humans, Models, Theoretical, Cost of Illness
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